Search Results - "Harris, Mathew A."

Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants by Ritchie, Stuart J, Cox, Simon R, Shen, Xueyi, Lombardo, Michael V, Reus, Lianne M, Alloza, Clara, Harris, Mathew A, Alderson, Helen L, Hunter, Stuart, Neilson, Emma, Liewald, David C M, Auyeung, Bonnie, Whalley, Heather C, Lawrie, Stephen M, Gale, Catharine R, Bastin, Mark E, McIntosh, Andrew M, Deary, Ian J

“…Abstract Sex differences in the human brain are of interest for many reasons: for example, there are sex differences in the observed prevalence of psychiatric…”
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Associations between vascular risk factors and brain MRI indices in UK Biobank by Cox, Simon R, Lyall, Donald M, Ritchie, Stuart J, Bastin, Mark E, Harris, Mathew A, Buchanan, Colin R, Fawns-Ritchie, Chloe, Barbu, Miruna C, de Nooij, Laura, Reus, Lianne M, Alloza, Clara, Shen, Xueyi, Neilson, Emma, Alderson, Helen L, Hunter, Stuart, Liewald, David C, Whalley, Heather C, McIntosh, Andrew M, Lawrie, Stephen M, Pell, Jill P, Tucker-Drob, Elliot M, Wardlaw, Joanna M, Gale, Catharine R, Deary, Ian J

“…Abstract Aims Several factors are known to increase risk for cerebrovascular disease and dementia, but there is limited evidence on associations between…”
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Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression by Rupprechter, Samuel, Romaniuk, Liana, Series, Peggy, Hirose, Yoriko, Hawkins, Emma, Sandu, Anca-Larisa, Waiter, Gordon D, McNeil, Christopher J, Shen, Xueyi, Harris, Mathew A, Campbell, Archie, Porteous, David, Macfarlane, Jennifer A, Lawrie, Stephen M, Murray, Alison D, Delgado, Mauricio R, McIntosh, Andrew M, Whalley, Heather C, Steele, J Douglas

“…Major depressive disorder is a leading cause of disability and significant mortality, yet mechanistic understanding remains limited. Over the past decade…”
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Patterns of brain atrophy in recently-diagnosed relapsing-remitting multiple sclerosis by Meijboom, Rozanna, York, Elizabeth N, Kampaite, Agniete, Harris, Mathew A, White, Nicole, Valdés Hernández, Maria Del C, Thrippleton, Michael J, MacDougall, N J J, Connick, Peter, Hunt, David P J, Chandran, Siddharthan, Waldman, Adam D

“…Recurrent neuroinflammation in relapsing-remitting MS (RRMS) is thought to lead to neurodegeneration, resulting in progressive disability. Repeated magnetic…”
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Aging specifically impairs switching to an allocentric navigational strategy by Harris, Mathew A, Wiener, Jan M, Wolbers, Thomas

“…Navigation abilities decline with age, partly due to deficits in numerous component processes. Impaired switching between these various processes (i.e.,…”
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Cognitive functioning and lifetime major depressive disorder in UK Biobank by de Nooij, Laura, Harris, Mathew A, Adams, Mark J, Clarke, Toni-Kim, Shen, Xueyi, Cox, Simon R, McIntosh, Andrew M, Whalley, Heather C

“…Cognitive impairment associated with lifetime major depressive disorder (MDD) is well-supported by meta-analytic studies, but population-based estimates remain…”
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Structural neuroimaging measures and lifetime depression across levels of phenotyping in UK biobank by Harris, Mathew A., Cox, Simon R., de Nooij, Laura, Barbu, Miruna C., Adams, Mark J., Shen, Xueyi, Deary, Ian J., Lawrie, Stephen M., McIntosh, Andrew M., Whalley, Heather C.

“…Depression is assessed in various ways in research, with large population studies often relying on minimal phenotyping. Genetic results suggest clinical…”
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Comparing personalized brain-based and genetic risk scores for major depressive disorder in large population samples of adults and adolescents by Thng, Gladi, Shen, Xueyi, Stolicyn, Aleks, Harris, Mathew A, Adams, Mark J, Barbu, Miruna C, Kwong, Alex S F, Frangou, Sophia, Lawrie, Stephen M, McIntosh, Andrew M, Romaniuk, Liana, Whalley, Heather C

“…Major depressive disorder (MDD) is a polygenic disorder associated with brain alterations but until recently, there have been no brain-based metrics to…”
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Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland by Green, Claire, Stolicyn, Aleks, Harris, Mathew A., Shen, Xueyi, Romaniuk, Liana, Barbu, Miruna C., Hawkins, Emma L., Wardlaw, Joanna M., Steele, J. Douglas, Waiter, Gordon D., Sandu, Anca-Larisa, Campbell, Archie, Porteous, David J., Seckl, Jonathan R., Lawrie, Stephen M., Reynolds, Rebecca M., Cavanagh, Jonathan, McIntosh, Andrew M., Whalley, Heather C.

“…Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable heterogeneity of…”
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Correction: Structural neuroimaging measures and lifetime depression across levels of phenotyping in UK biobank by Harris, Mathew A., Cox, Simon R., de Nooij, Laura, Barbu, Miruna C., Adams, Mark J., Shen, Xueyi, Deary, Ian J., Lawrie, Stephen M., McIntosh, Andrew M., Whalley, Heather C.

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Early-life predictors of resilience and related outcomes up to 66 years later in the 6-day sample of the 1947 Scottish mental survey by Harris, Mathew A., Brett, Caroline E., Starr, John M., Deary, Ian J., McIntosh, Andrew M.

“…Purpose Psychological resilience, the ability to manage and quickly recover from stress and trauma, is associated with a range of health and wellbeing…”
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How age-related strategy switching deficits affect wayfinding in complex environments by Harris, Mathew A, Wolbers, Thomas

“…Abstract Although most research on navigation in aging focuses on allocentric processing deficits, impaired strategy switching may also contribute to…”
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Changes in bird assemblages because of vegetation homogenisation in communal livestock systems by Harris, Mathew A., Greve, Michelle, Voysey, Michael D., Jamison, Samantha-Leigh

“…Protected areas are intended to promote biodiversity representation and persistence; yet, whether they are effective in degraded landscapes where much of the…”
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Ageing effects on path integration and landmark navigation by Harris, Mathew A., Wolbers, Thomas

“…Navigation abilities show marked decline in both normal ageing and dementia. Path integration may be particularly affected, as it is supported by the…”
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Personality Stability From Age 14 to Age 77 Years by Harris, Mathew A, Brett, Caroline E, Johnson, Wendy, Deary, Ian J

“…There is evidence for differential stability in personality trait differences, even over decades. The authors used data from a sample of the Scottish Mental…”
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Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals by Shi, Liu, Buchanan, Colin R., Cox, Simon R., Hillary, Robert F., Marioni, Riccardo E., Campbell, Archie, Hayward, Caroline, Stolicyn, Aleks, Whalley, Heather C., Harris, Mathew A., Waymont, Jennifer, Waiter, Gordon, Backhouse, Ellen, Wardlaw, Joanna M., Steele, Douglas, Mcintosh, Andrew, Lovestone, Simon, Buckley, Noel J., Nevado‐Holgado, Alejo J.

“…Introduction This study aims to first discover plasma proteomic biomarkers relating to neurodegeneration (N) and vascular (V) damage in cognitively normal…”
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Maladaptive bias for extrahippocampal navigation strategies in aging humans by Wiener, Jan M, de Condappa, Olivier, Harris, Mathew A, Wolbers, Thomas

“…Efficient spatial navigation requires not only accurate spatial knowledge but also the selection of appropriate strategies. Using a novel paradigm that allowed…”
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Longitudinal trajectories of brain age in young individuals at familial risk of mood disorder from the Scottish Bipolar Family Study by de Nooij, Laura, Harris, Mathew A., Hawkins, Emma L., Clarke, Toni-Kim, Shen, Xueyi, Chan, Stella W. Y., Ziermans, Tim B., McIntosh, Andrew M., Whalley, Heather C.

“…Background: Within young individuals, mood disorder onset may be related to changes in trajectory of brain structure development. To date, however,…”
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Longitudinal trajectories of brain age in young individuals at familial risk of mood disorder from the Scottish Bipolar Family Study by de Nooij, Laura, Harris, Mathew A, Hawkins, Emma L, Clarke, Toni-Kim, Shen, Xueyi, Chan, Stella W Y, Ziermans, Tim B, McIntosh, Andrew M, Whalley, Heather C

“…Within young individuals, mood disorder onset may be related to changes in trajectory of brain structure development. To date, however, longitudinal…”
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Wakeful rest promotes the integration of spatial memories into accurate cognitive maps by Craig, Michael, Dewar, Michaela, Harris, Mathew A., Della Sala, Sergio, Wolbers, Thomas

“…ABSTRACT Flexible spatial navigation, e.g. the ability to take novel shortcuts, is contingent upon accurate mental representations of environments‐cognitive…”
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