Search Results - "Harris, Joel M."

Single-Molecule Kinetic Investigation of Cocaine-Dependent Split-Aptamer Assembly by Morris, Frances D, Peterson, Eric M, Heemstra, Jennifer M, Harris, Joel M

“…Aptamers are short nucleic-acid biopolymers selected to have high affinity and specificity for protein or small-molecule target analytes. Aptamers can be…”
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Adapting confocal Raman microscopy for in situ studies of redox transformations at electrode-electrolyte interfaces by Korzeniewski, Carol, Peterson, Eric M., Kitt, Jay P., Minteer, Shelley D., Harris, Joel M.

“…Confocal Raman microscopy was applied to quantify redox species present within the diffusion layer adjacent to an electrode surface under potentiostatic…”
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Confocal Raman Microscopy for pH-Gradient Preconcentration and Quantitative Analyte Detection in Optically Trapped Phospholipid Vesicles by Hardcastle, Chris D, Harris, Joel M

“…The ability of a vesicle membrane to preserve a pH gradient, while allowing for diffusion of neutral molecules across the phospholipid bilayer, can provide the…”
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Single Layer Graphene for Estimation of Axial Spatial Resolution in Confocal Raman Microscopy Depth Profiling by Korzeniewski, Carol, Kitt, Jay P, Bukola, Saheed, Creager, Stephen E, Minteer, Shelley D, Harris, Joel M

“…Single layer graphene (SLG), with its angstrom-scale thickness and strong Raman scattering cross section, was adapted for measurement of the axial…”
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Detecting Phase Transitions in Phosphatidylcholine Vesicles by Raman Microscopy and Self-Modeling Curve Resolution by Fox, Christopher B, Uibel, Rory H, Harris, Joel M

“…The study of phospholipid phase transitions is important for understanding drug− and protein−membrane interactions as well as other phenomena such as…”
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Electrostatic-Gated Transport in Chemically Modified Glass Nanopore Electrodes by Wang, Gangli, Zhang, Bo, Wayment, Joshua R, Harris, Joel M, White, Henry S

“…Electrostatic-gated transport in chemically modified glass nanopore electrodes with orifice radii as small as 15 nm is reported. A single conical-shaped…”
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Surface-Enhanced Raman Scattering Study of the Kinetics of Self-Assembly of Carboxylate-Terminated n-Alkanethiols on Silver by Ma, Chaoxiong, Harris, Joel M.

“…Adsorption of 11-mercaptoundecanoic acid (MUA) on silver from methanol and aqueous solutions was monitored in situ by surface-enhanced Raman scattering (SRES)…”
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Confocal Raman Microscopy Probing of Temperature-Controlled Release from Individual, Optically-Trapped Phospholipid Vesicles by Schaefer, Jonathan J, Ma, Chaoxiong, Harris, Joel M

“…Control of permeability of phospholipid vesicle (liposome) membranes is critical to their applications in analytical sensing, in fundamental studies of…”
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Single-Layer Graphene Sandwiched between Proton-Exchange Membranes for Selective Proton Transmission by Bukola, Saheed, Beard, Kyle, Korzeniewski, Carol, Harris, Joel M, Creager, Stephen E

“…Proton transmission through single-layer CVD graphene in graphene/proton-exchange-membrane (PEM) sandwich structures is found to be more than 100 times faster…”
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Quantitative Detection of Single Molecules in Fluorescence Microscopy Images by Peterson, Eric M, Harris, Joel M

“…Fluorescence imaging and counting of single molecules adsorbed or bound to surfaces are being employed in a number of quantitative analysis applications…”
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Confocal Raman microscopy for simultaneous monitoring of partitioning and disordering of tricyclic antidepressants in phospholipid vesicle membranes by Fox, Christopher B., Harris, Joel M.

“…Characterization of drug–membrane interactions is important in order to understand the mechanisms of action of drugs and to design more effective drugs and…”
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Microscopic Rates of Peptide–Phospholipid Bilayer Interactions from Single-Molecule Residence Times by Myers, Grant A, Gacek, Daniel A, Peterson, Eric M, Fox, Christopher B, Harris, Joel M

“…The binding of glucagon-like peptide-1 (GLP-1) to a planar phospholipid bilayer is measured using single-molecule total internal reflection fluorescence…”
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Single Molecule Tracking Studies of Lower Critical Solution Temperature Transition Behavior in Poly(N-isopropylacrylamide) by Elliott, Lindsay C. C, Barhoum, Moussa, Harris, Joel M, Bohn, Paul W

“…Spatial and temporal heterogeneities in expanded and collapsed surface bound poly(N-isopropylacrylamide), pNIPAAm, films are studied by single molecule…”
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Optical-Trapping Raman Microscopy Detection of Single Unilamellar Lipid Vesicles by Cherney, Daniel P, Conboy, John C, Harris, Joel M

“…Raman spectra of individual unilamellar phospholipid vesicles (∼0.6 μm in size) have been acquired by optical-trapping confocal Raman microscopy over the…”
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Confocal Raman microscopy of optical-trapped particles in liquids by Cherney, Daniel P, Harris, Joel M

“…The in situ analysis of small, dispersed particles in liquids is a challenging problem, the successful solution to which influences diverse applications of…”
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A Flexible Approach toward Trisubstituted Piperidines and Indolizidines:  Synthesis of 6-epi-Indolizidine 223A by HARRIS, Joel M., PADWA, Albert

“…2,5,6-Trisubstituted piperidines are readily prepared by a combination of an aza-Achmatowicz oxidation of a furyl-substituted benzenesulfonamide followed by a…”
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Spatially Resolved Analysis of Small Particles by Confocal Raman Microscopy:  Depth Profiling and Optical Trapping by Bridges, Travis E, Houlne, Michael P, Harris, Joel M

“…Raman microscopy is a powerful method to provide spatially resolved information about the chemical composition of materials. With confocal collection optics,…”
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Structural Characterization of Individual Vesicles using Fluorescence Microscopy by Heider, Emily C, Barhoum, Moussa, Edwards, Kyle, Gericke, Karl-Heinz, Harris, Joel M

“…Extrusion of hydrated lipid suspensions is frequently employed to produce vesicles of uniform size, and the resulting vesicles are often reported to be…”
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Nanomolar Binding of an Antibiotic Peptide to DNA Measured with Raman Spectroscopy by Myres, Grant J., Harris, Joel M.

“…Immobilization of DNA to surfaces offers a convenient means of screening the binding affinity and selectivity of potential small-molecule therapeutic…”
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Stable Immobilization of DNA to Silica Surfaces by Sequential Michael Addition Reactions Developed with Insights from Confocal Raman Microscopy by Myres, Grant J., Harris, Joel M.

“…The immobilization of DNA to surfaces is required for numerous biosensing applications related to the capture of target DNA sequences, proteins, or…”
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