Search Results - "Harris, J. Robin"

Transmission electron microscopy in molecular structural biology: A historical survey by Harris, J. Robin

“…•This review article covers the historical development and application of TEM.•Emphasis is placed on molecular structural biology.•Early applications in the…”
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Negative staining and cryo-negative staining of macromolecules and viruses for TEM by De Carlo, Sacha, Harris, J. Robin

“…In this review we cover the technical background to negative staining of biomolecules and viruses, and then expand upon the different possibilities and…”
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In vitro fibrillogenesis of collagen type I in varying ionic and pH conditions by Harris, J. Robin, Soliakov, Andrei, Lewis, Richard J.

“…Collagen is the most abundant protein in the human body, and has primary roles in the formation of tendons, cartilage and bone, it provides mechanical strength…”
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Structure, mechanism and regulation of peroxiredoxins by Wood, Zachary A, Schröder, Ewald, Robin Harris, J, Poole, Leslie B

“…Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels which mediate signal transduction in…”
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Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide by Milton, Nathaniel G.N., Harris, J. Robin

“…► First demonstration of the ability of native rat amylin 1–37 to form fibrils. ► Conditions required for nanofibril formation have been identified. ► The…”
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Visualizing In Vitro Type I Collagen Fibrillogenesis by Transmission Electron Microscopy by Harris, J Robin

“…Techniques and protocols for the in vitro formation of collagen type I fibrils and the extensive biochemical variation of the fibrillogenesis conditions are…”
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Micelle Formation from Amphiphilic "Cylindrical Brush"-Coil Block Copolymers Prepared by Metallocene Catalysis by Neiser, Michael W., Muth, Sandra, Kolb, Ute, Harris, J. Robin, Okuda, Jun, Schmidt, Manfred

“…Giant rod–coil amphiphilic block copolymers were prepared by metallocene‐catalyzed polymerization. The hydrophilic coiled block consists of polymethacrylic…”
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Morphology and In Vitro Infectivity of Sporozoites of Cryptosporidium parvum by Petry, Franz, Kneib, Inka, Harris, J. Robin

“…An important obstacle in studying Cryptosporidium parvum is the lack of a permanent in vitro cultivation system of the parasite. While short-term cultures…”
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Native and subunit molecular mass and quarternary structure of the hemoglobin from the primitive branchiopod crustacean Triops cancriformis by Rousselot, Morgane, Jaenicke, Elmar, Lamkemeyer, Tobias, Harris, J. Robin, Pirow, Ralph

“…Many branchiopod crustaceans are endowed with extracellular, high‐molecular‐weight hemoglobins whose exact structural characteristics have remained a matter of…”
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Human islet amyloid polypeptide fibril binding to catalase: a transmission electron microscopy and microplate study by Milton, Nathaniel G N, Harris, J Robin

“…The diabetes-associated human islet amyloid polypeptide (IAPP) is a 37-amino-acid peptide that forms fibrils in vitro and in vivo. Human IAPP fibrils are toxic…”
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Outer Membrane Protein F Stabilised with Minimal Amphipol Forms Linear Arrays and LPS-Dependent 2D Crystals by Arunmanee, Wanatchaporn, Harris, J. Robin, Lakey, Jeremy H.

“…Amphipols (APol) are polymers which can solubilise and stabilise membrane proteins (MP) in aqueous solutions. In contrast to conventional detergents, APol are…”
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An Aqueous Extract of Withania somnifera Root Inhibits Amyloid β Fibril Formation In Vitro by Kumar, Suresh, Harris, Robin J., Seal, Christopher J., Okello, Edward J.

“…The ability of an aqueous extract of W. somnifera L. Dunal (Family: Solanaceae) roots to inhibit fibril formation by the amyloid‐β peptide in vitro was…”
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The collagen type I segment long spacing (SLS) and fibrillar forms: Formation by ATP and sulphonated diazo dyes by Harris, J. Robin, Lewis, Richard J.

“…•We have addressed biochemical parameters such as the ATP concentration, pH, speed of formation and stability so as to provide a more complete structural…”
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Negative staining of thinly spread biological samples by Harris, J Robin

“…Negative staining is widely applicable to isolated viruses, protein molecules, macro-molecular assemblies and fibrils, subcellular membrane fractions,…”
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Recombinant anthrax protective antigen: Observation of aggregation phenomena by TEM reveals specific effects of sterols by Harris, J. Robin, Soliakov, Andrei, Watkinson, Allan, Lakey, Jeremy H.

“…•rPA83 forms fibrous aggregates when heated at low temperatures (50°C).•rPA83 aggregates binds to the edges of cholesterol bilayer microcrystals.•PA63 prepore…”
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Cholesterol binding to amyloid-β fibrils: A TEM study by Harris, J. Robin

“…There is increasing interest in the role of brain cholesterol in Alzheimer's disease and the contribution of cholesterol to the formation of amyloid plaques…”
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Influence of saline and pH on collagen type I fibrillogenesis in vitro: Fibril polymorphism and colloidal gold labelling by Harris, J. Robin, Reiber, Andreas

“…We have produced different collagen type I fibrils by in vitro fibrillogenesis of acetic acid-soluble collagen within the pH range 2.5–9.0, in the presence and…”
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Proclaiming Library Worth in a Program Prioritization Process at a Mid-Sized Public University by Oh, Michelle J., Harris, Robin J., Wallis, Lisa C.

“…In an economic climate when colleges can no longer presume that legislators see institutions of higher learning as tacit public goods, institutions around the…”
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Topology of the 10 subunits within the Decamer of KLH, the hemocyanin of the marine gastropod Megathura crenulata by Gebauer, Wolfgang, Robin Harris, J., Markl, Jürgen

“…Immunoelectron microscopy has been performed using negatively stained immune complexes of keyhole limpet hemocyanin isoform 1 (KLH1) decamers and a functional…”
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Introduction: Protein Oligomerization and the Formation of Macromolecular Assemblies by Harris, J Robin, Marles-Wright, Jon

“…The ability of biomolecules to link together to form higher order assemblies underlies much of cellular structure and function. Here we emphasise protein…”
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