Search Results - "Harris, Ian R."
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RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells
Published in Journal of translational medicine (13-03-2018)“…Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly characterized by retinal pigment epithelium (RPE) degeneration with…”
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Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins
Published in The Journal of neuroscience (25-11-2015)“…Cell therapy demonstrates great potential for the treatment of neurological disorders. Human umbilical tissue-derived cells (hUTCs) were previously shown to…”
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Immunogenicity of umbilical cord tissue–derived cells
Published in Blood (01-01-2008)“…Umbilical cord tissue provides a unique source of cells with potential for tissue repair. Umbilical cord tissue–derived cells (UTCs) are MHC class I (MHCI)…”
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A simulation method for the macro-meteorological wind speed and the implications for extreme value analysis
Published in Journal of wind engineering and industrial aerodynamics (01-02-2014)“…This paper provides a contribution to the testing of existing methods of analysis of extreme wind speeds and to the development of better alternatives. A…”
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Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity
Published in The Journal of neuroscience (21-03-2018)“…Human umbilical tissue-derived cells (hUTC or palucorcel) are currently under clinical investigation for the treatment of geographic atrophy, a late stage of…”
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Human umbilical tissue‐derived cells rescue retinal pigment epithelium dysfunction in retinal degeneration
Published in Stem cells (Dayton, Ohio) (01-02-2016)“…Retinal pigment epithelium (RPE) cells perform many functions crucial for retinal preservation and vision. RPE cell dysfunction results in various retinal…”
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Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease
Published in Stem cells (Dayton, Ohio) (01-03-2007)“…Progressive photoreceptor degeneration resulting from genetic and other factors is a leading and largely untreatable cause of blindness worldwide. The object…”
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XIMIS, a penultimate extreme value method suitable for all types of wind climate
Published in Journal of wind engineering and industrial aerodynamics (01-08-2009)“…This paper introduces XIMIS, an extended version of the existing IMIS method. The new method is penultimate in that it does not rely on asymptotic results,…”
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UVB irradiation up-regulates serine palmitoyltransferase in cultured human keratinocytes
Published in Journal of lipid research (01-10-1998)“…The enzyme serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the first committed and rate-limiting step in sphingolipid synthesis, is…”
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Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization
Published in Molecular therapy. Methods & clinical development (13-09-2019)“…Exudative age-related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the leading cause of irreversible blindness in…”
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The minimum L2 distance estimator for Poisson mixture models
Published in Journal of statistical planning and inference (01-03-2011)Get full text
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Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis
Published in Journal of lipid research (01-02-1998)“…After permeability barrier perturbation there is an increase in the mRNA levels for key enzymes necessary for lipid synthesis in the epidermis. The…”
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Exact and general FT1 penultimate distributions of extreme wind speeds drawn from tail-equivalent Weibull parents
Published in Structural safety (01-01-2004)“…We present a contribution to the current debate on methodologies for assessing extreme wind speeds. We review long-established extreme theory in the light of…”
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Postscript to “Exact and general FT1 penultimate distributions of extreme wind speeds drawn from tail-equivalent Weibull parents”
Published in Structural safety (01-01-2008)“…We present a further contribution to the current debate on methodologies for assessing extreme wind speeds, adding further insights to a recent paper which…”
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Regulation of HMG-CoA Synthase and HMG-CoA Reductase by Insulin and Epidermal Growth Factor in HaCaT Keratinocytes
Published in Journal of investigative dermatology (01-01-2000)“…Synthesis of cholesterol, via the isoprenoid/mevalonate pathway, is required for keratinocyte growth and differentiation, and maintenance of the stratum…”
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A comparison of related density‐based minimum divergence estimators
Published in Biometrika (01-10-2001)“…This paper compares the minimum divergence estimator of Basu et al. (1998) to a competing minimum divergence estimator which turns out to be equivalent to a…”
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A Family of Sequences which Converge to the Euler-Mascheroni Constant
Published in Carpathian Journal of Mathematics (01-01-2024)“…This article considers the Euler-Mascheroni constant (γ) as the limit of a continuous function. Graphs of the function shed light on some familiar…”
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Extreme wind speeds in mixed climates revisited
Published in Journal of wind engineering and industrial aerodynamics (01-02-2003)“…The methodology for the analysis of extreme wind speeds in mixed climates originally proposed in 1978 by Gomes and Vickery is updated to take advantage of…”
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Restoring function and aesthetics in a patient previously treated for amelogenesis imperfecta
Published in The European journal of prosthodontics and restorative dentistry (01-12-2009)“…A 26-year-old male patient presented with generalised gingival recession related to the margins of crowns fitted between the ages of 12 and 15 years. The…”
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The Level Crossing Method applied to mean wind speeds from “mixed” climates
Published in Structural safety (01-07-2017)“…•Re-examination of theory of original Level Crossing Method.•Confirmation of errors by checking against synthetic data.•New theoretical result for level…”
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