Search Results - "Harris, David C.H."

Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells by Zheng, Guoping, Lyons, James Guy, Tan, Thian Kui, Wang, Yiping, Hsu, Tzu-Ting, Min, Danqing, Succar, Lena, Rangan, Gopala K, Hu, Min, Henderson, Beric R, Alexander, Stephen I, Harris, David C.H

“…Epithelial-mesenchymal transition (EMT) plays an important role in organ fibrosis, including that of the kidney. Loss of E-cadherin expression is a hallmark of…”
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Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells by Tan, Thian Kui, Zheng, Guoping, Hsu, Tzu-Ting, Wang, Ying, Lee, Vincent W.S, Tian, Xinrui, Wang, Yiping, Cao, Qi, Wang, Ya, Harris, David C.H

“…As a rich source of pro-fibrogenic growth factors and matrix metalloproteinases (MMPs), macrophages are well-placed to play an important role in renal…”
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By Homing to the Kidney, Activated Macrophages Potently Exacerbate Renal Injury by Wang, Ying, Wang, Yiping, Cai, Qi, Zheng, Guoping, Lee, Vincent W.S, Zheng, Dong, Li, Xiaomei, Tan, Thian Kui, Harris, David C.H

“…Macrophages are important mediators of injury in most types of human kidney diseases; however, the pathogenic importance of both macrophage number and…”
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Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury by Cao, Qi, Wang, Yiping, Niu, Zhiguo, Wang, Chengshi, Wang, Ruifeng, Zhang, Zhiqiang, Chen, Titi, Wang, Xin Maggie, Li, Qing, Lee, Vincent W S, Huang, Qingsong, Tan, Jing, Guo, Minghao, Wang, Yuan Min, Zheng, Guoping, Yu, Di, Alexander, Stephen I, Wang, Hui, Harris, David C H

“…The IL-33-type 2 innate lymphoid cell (ILC2) axis has an important role in tissue homeostasis, inflammation, and wound healing. However, the relative…”
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Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy by Cao, Qi, Wang, Yiping, Wang, Xin Maggie, Lu, Junyu, Lee, Vincent W S, Ye, Qianling, Nguyen, Hanh, Zheng, Guoping, Zhao, Ye, Alexander, Stephen I, Harris, David C H

“…Conventional markers of macrophages (Mфs) and dendritic cells (DCs) lack specificity and often overlap, leading to confusion and controversy regarding the…”
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The role of the immune system in the pathogenesis of hypertension by Lee, Vincent W S, Wang, Yiping, Harris, David C H

“…The role of innate and adaptive immunity in the pathogenesis of hypertension has received increasing recognition over the past few years. This review will…”
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Global case studies for chronic kidney disease/end-stage kidney disease care by Yang, Chih-Wei, Harris, David C.H., Luyckx, Valerie A., Nangaku, Masaomi, Hou, Fan Fan, Garcia Garcia, Guillermo, Abu-Aisha, Hasan, Niang, Abdou, Sola, Laura, Bunnag, Sakarn, Eiam-Ong, Somchai, Tungsanga, Kriang, Richards, Marie, Richards, Nick, Goh, Bak Leong, Dreyer, Gavin, Evans, Rhys, Mzingajira, Henry, Twahir, Ahmed, McCulloch, Mignon I., Ahn, Curie, Osafo, Charlotte, Hsu, Hsiang-Hao, Barnieh, Lianne, Donner, Jo-Ann, Tonelli, Marcello

“…The prevalence of chronic kidney disease and its risk factors is increasing worldwide, and the rapid rise in global need for end-stage kidney disease care is a…”
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Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo by Cao, Qi, Wang, Yiping, Zheng, Dong, Sun, Yan, Wang, Changqi, Wang, Xin M, Lee, Vincent W S, Wang, Ya, Zheng, Guoping, Tan, Thian K, Wang, Yuan M, Alexander, Stephen I, Harris, David C H

“…Alternatively activated macrophages (M2) regulate immune responses and ex vivo polarized splenic M2 are able to ameliorate renal injury including models of…”
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α3 Integrin of Cell-Cell Contact Mediates Kidney Fibrosis by Integrin-Linked Kinase in Proximal Tubular E-Cadherin Deficient Mice by Zheng, Guoping, Zhang, Jianlin, Zhao, Hong, Wang, Hailong, Pang, Min, Qiao, Xi, Lee, So R, Hsu, Tzu-Ting, Tan, Thian K, Lyons, J. Guy, Zhao, Ye, Tian, Xinrui, Loebel, David A.F, Rubera, Isabella, Tauc, Michel, Wang, Ya, Wang, Yiping, Wang, Yuan M, Cao, Qi, Wang, Changqi, Lee, Vincent W.S, Alexander, Stephen I, Tam, Patrick P.L, Harris, David C.H

“…Loss of E-cadherin marks a defect in epithelial integrity and polarity during tissue injury and fibrosis. Whether loss of E-cadherin plays a causal role in…”
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Emerging therapies for chronic kidney disease: what is their role? by Vilayur, Eswari, Harris, David C. H

“…The prevalence of chronic kidney disease (CKD) is increasing worldwide. The best therapies currently available aim to control blood pressure and maximize…”
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Effect of Early Initiation of Dialysis on Cardiac Structure and Function: Results From the Echo Substudy of the IDEAL Trial by Whalley, Gillian A., PhD, Marwick, Tom H., PhD, Doughty, Robert N., MD, Cooper, Bruce A., PhD, Johnson, David W., PhD, Pilmore, Andrew, BSc, Harris, David C.H., MD, Pollock, Carol A., PhD, Collins, John F., MBChB

“…Background Abnormalities of cardiac structure and function are common in patients undergoing dialysis, and cardiovascular disease is the major cause of…”
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Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus by Zheng, Dong, Wang, Yiping, Cao, Qi, Lee, Vincent W S, Zheng, Guoping, Sun, Yan, Tan, Thian K, Wang, Ya, Alexander, Stephen I, Harris, David C H

“…Alternatively activated macrophages (M2 macrophages) are able to reduce renal injury in murine adriamycin nephropathy. However, the effect of M2 macrophages in…”
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Type 2 innate lymphoid cells are protective against hepatic ischaemia/reperfusion injury by Cao, Qi, Wang, Ruifeng, Niu, Zhiguo, Chen, Titi, Azmi, Farhana, Read, Scott A., Chen, Jianwei, Lee, Vincent W.S., Zhou, Chunze, Julovi, Sohel, Huang, Qingsong, Wang, Yuan Min, Starkey, Malcolm R., Zheng, Guoping, Alexander, Stephen I., George, Jacob, Wang, Yiping, Harris, David C.H.

“…Background and AimsAlthough type 2 innate lymphoid cells (ILC2s) were originally found to be liver-resident lymphocytes, the role and importance of ILC2 in…”
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International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in South Asia by Divyaveer, Smita S., Ramachandran, Raja, Sahay, Manisha, Singh Shah, Dibya, Akhtar, Fazal, Bello, Aminu K., Iyengar, Arpana, Johnson, David W., Harris, David C.H., Levin, Adeera, Lunney, Meaghan, Rahman, Muhibur, Rashid, Harun-Ur, Saad, Syed, Zaidi, Deenaz, Osman, Mohamed A., Varughese, Santosh, Wijewickrama, Eranga S., Khan, Maryam, Ye, Feng, Tonelli, Marcello, Okpechi, Ikechi G., Jha, Vivekanand

“…Information about disease burden and the available infrastructure and workforce to care for patients with kidney disease was collected for the second edition…”
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Participant Perceptions in a Long-term Clinical Trial of Autosomal Dominant Polycystic Kidney Disease by Amin, Sneha, Sangadi, Irene, Allman-Farinelli, Margaret, Badve, Sunil V., Boudville, Neil, Coolican, Helen, Coulshed, Susan, Foster, Sheryl, Fernando, Mangalee, Haloob, Imad, Harris, David C.H., Hawley, Carmel M., Holt, Jane, Howell, Martin, Kumar, Karthik, Johnson, David W., Lee, Vincent W., Mai, Jun, Rangan, Anna, Roger, Simon D., Sud, Kamal, Torres, Vicente, Vilayur, Eswari, Rangan, Gopala K.

“…The development of new therapies for autosomal dominant polycystic kidney disease requires clinical trials to be conducted efficiently. In this study, the…”
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Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events by Wang, Yang, Wang, Yi Ping, Tay, Yuet-Ching, Harris, David C.H.

“…Progressive adriamycin nephropathy in mice: Sequence of histologic and immunohistochemical events. As an experimental analogue of human focal glomerular…”
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Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease by Zheng, Dong, Cao, Qi, Lee, Vincent W S, Wang, Ya, Zheng, Guoping, Wang, YuanMin, Tan, Thian Kui, Wang, Changqi, Alexander, Stephen I, Harris, David C H, Wang, Yiping

“…Plasmacytoid dendritic cells play important roles in inducing immune tolerance, preventing allograft rejection, and regulating immune responses in both…”
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Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease by Ta, Michelle H. T., Rao, Padmashree, Korgaonkar, Mayuresh, Foster, Sheryl F., Peduto, Anthony, Harris, David C. H., Rangan, Gopala K.

“…Heterocyclic dithiocarbamates have anti‐inflammatory and anti‐proliferative effects in rodent models of chronic kidney disease. In this study, we tested the…”
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Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease by Kairaitis, Lukas, Wang, Yiping, Zheng, Ling, Tay, Yuet-Ching, Wang, Yang, Harris, David C.H.

“…Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease. Interaction between CD40 and CD40 ligand (CD40L) is involved…”
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Role of CD8+ cells in the progression of murine adriamycin nephropathy by Wang, Yang, Wang, Yi Ping, Tay, Yuet-Ching, Harris, David C.H.

“…Role of CD8+ cells in the progression of murine adriamycin nephropathy. Many studies have shown that interstitial inflammation in human and experimental renal…”
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