Search Results - "Harris, Bethany D."

Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern by Deshpande, Ashlesha, Harris, Bethany D., Martinez-Sobrido, Luis, Kobie, James J., Walter, Mark R.

“…Severe acute respiratory syndrome coronavirus-2 (SAR-CoV-2) causes coronavirus disease 2019 (COVID19) that is responsible for short and long-term disease, as…”
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Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines by Logsdon, Naomi J, Deshpande, Ashlesha, Harris, Bethany D, Rajashankar, Kanagalaghatta R, Walter, Mark R

“…Interleukin 20 (IL-20) is a pleotropic IL-10 family cytokine that protects epithelial surfaces from pathogens. However, dysregulated IL-20 signaling is…”
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Human interferon-ϵ and interferon-κ exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R by Harris, Bethany D., Schreiter, Jessica, Chevrier, Marc, Jordan, Jarrat L., Walter, Mark R.

“…IFNϵ and IFNκ are interferons that induce microbial immunity at mucosal surfaces and in the skin. They are members of the type-I interferon (IFN) family, which…”
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Relaxin (RLX) and estrogen affect estrogen receptor α, vascular endothelial growth factor, and RLX receptor expression in the neonatal porcine uterus and cervix by Yan, Wenbo, Chen, Joseph, Wiley, Anne A, Crean-Harris, Bethany D, Bartol, Frank F, Bagnell, Carol A

“…The porcine female reproductive tract undergoes estrogen receptor (ER) α-dependent development after birth (postnatal day=PND 0), the course of which can…”
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Characterization of Type-I IFN subtype autoantibodies and activity in SLE serum and urine by Harris, Bethany D, Kuruganti, Srilalitha, Deshpande, Ashlesha, Goepfert, Paul A, Chatham, W Winn, Walter, Mark R

“…Background/objective Type-I interferons contribute to pathogenesis in systemic lupus erythematosus, including nephritis. Interferons consist of a family of 16…”
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Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain by Yoon, Sung-il, Jones, Brandi C., Logsdon, Naomi J., Harris, Bethany D., Deshpande, Ashlesha, Radaeva, Svetlana, Halloran, Brian A., Gao, Bin, Walter, Mark R.

“…IL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokines (IL-10, IL-22, IL-26, IL-28, and IL-29) that play critical…”
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Epstein-Barr Virus IL-10 Engages IL-10R1 by a Two-step Mechanism Leading to Altered Signaling Properties by Yoon, Sung Il, Jones, Brandi C., Logsdon, Naomi J., Harris, Bethany D., Kuruganti, Srilalitha, Walter, Mark R.

“…Human interleukin-10 (hIL-10) is a pleiotropic cytokine that is able to suppress or activate cellular immune responses to protect the host from invading…”
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Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes by Kuruganti, Srilalitha, Miersch, Shane, Deshpande, Ashlesha, Speir, Jeffrey A., Harris, Bethany D., Schriewer, Jill M., Buller, R. Mark L., Sidhu, Sachdev S., Walter, Mark R.

“…Exogenous cytokine therapy can induce systemic toxicity, which might be prevented by activating endogenously produced cytokines in local cell niches. Here we…”
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Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain by Yoon, Sung-il, Jones, Brandi C., Logsdon, Naomi J., Harris, Bethany D., Deshpande, Ashlesha, Radaeva, Svetlana, Halloran, Brian A., Gao, Bin, Walter, Mark R.

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Neonatal Exposure to Estrogen and Estrogen Receptor Agonists and Antagonists: Effects on the Adult Endometrial Proteome and Morphoregulatory Gene Expression in the Neonatal Uterus by Harris, Bethany D

“…Development of the porcine uterus begins prenatally but is completed postnatally. In mammals, the uterus provides an embryotrophic environment for conceptus…”
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