Search Results - "Harquail, Jason"
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Deoxypodophyllotoxin isolated from Juniperus communis induces apoptosis in breast cancer cells
Published in Anti-cancer agents in medicinal chemistry (01-01-2015)“…The study of anticancer properties from natural products has regained popularity as natural molecules provide a high diversity of chemical structures with…”
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2
Pathogenic variants carrier screening in New Brunswick: Acadians reveal high carrier frequency for multiple genetic disorders
Published in BMC medical genomics (29-04-2022)“…Founder populations that have recently undergone important genetic bottlenecks such as French-Canadians and Ashkenazi Jews can harbor some pathogenic variants…”
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3
CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (10-07-2015)“…Breast cancer is the second leading cause of death amongst women worldwide. As a result, many have turned their attention to new alternative approaches to…”
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4
Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs
Published in Molecular carcinogenesis (01-07-2016)“…Mammaglobin 1 (MGB1), a member of the secretoglobin family, is expressed in mammary epithelial tissues and is overexpressed in most mammary carcinomas. Despite…”
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Intracellular expression of inflammatory proteins S100A8 and S100A9 leads to epithelial-mesenchymal transition and attenuated aggressivity of breast cancer cells
Published in Anti-cancer agents in medicinal chemistry (01-01-2014)“…S100 inflammatory proteins have been previously shown to modulate breast cancer processes. More specifically, genome-wide transcriptome studies associate…”
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Elucidation of the Pax‐5/miRNA interactome and its oncogenic effects in cancer cells
Published in The FASEB journal (01-04-2019)“…The Pax‐5 oncogene has consistently been associated to B cell cancer lesions and more recently solid tumors including breast carcinoma. Although Pax‐5…”
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miRNAs 484 and 210 regulate Pax-5 expression and function in breast cancer cells
Published in Carcinogenesis (New York) (22-08-2019)“…Abstract Recent studies have enabled the identification of important factors regulating cancer progression, such as paired box gene 5 (Pax-5). This…”
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Pax-5 Inhibits Breast Cancer Proliferation Through MiR-215 Up-regulation
Published in Anticancer research (01-09-2018)“…In breast cancer, Pax-5 promotes pro-epithelial features and suppresses malignant cancer processes. However, the molecular mechanism of this antitumor activity…”
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Abstract P4-07-10: MiRNAs are important regulators of Pax-5 expression and function during breast cancer progression
Published in Cancer research (Chicago, Ill.) (01-05-2015)“…Abstract Recent studies have enabled the identification of important factors regulating cancer progression, one of these being the Pax-5 gene. Pax-5, an…”
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10
Pax-5 Inhibits NF-κB Activity in Breast Cancer Cells Through IKKε and miRNA-155 Effectors
Published in Journal of mammary gland biology and neoplasia (01-09-2018)“…Pax-5 , an essential transcription factor in B cell development, is aberrantly expressed in various B cell cancer lesions and solid tumors such as breast…”
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11
MicroRNAs and breast cancer malignancy: an overview of miRNA-regulated cancer processes leading to metastasis
Published in Cancer biomarkers : section A of Disease markers (01-01-2012)“…Cancer statistics show significant diagnosis numbers amongst men and women worldwide, where breast cancer is by far the most frequently diagnosed cancer in…”
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SaO048PROCALCITONIN IN END-STAGE KIDNEY DISEASE: DEFINING EXPECTED RANGES
Published in Nephrology, dialysis, transplantation (01-05-2018)Get full text
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13
Abstract 3094: MiRNAs 484 and 210 control Pax-5 expression and function in breast cancer
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Every hour, approximately 21 people are diagnosed with cancer where 9 will succumb to their disease. Recent studies have enabled the identification of…”
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14
Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways
Published in Journal of Cancer (01-01-2016)“…The study of genetic factors regulating breast cancer malignancy is a top priority to mitigate the morbidity and mortality associated with this disease. One of…”
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Co-régulation de Pax-5 et des microarns dans le cancer du sein
Published 01-01-2019“…Pax-5, un facteur de transcription essentiel dans le développement de cellules B, est exprimé de façon aberrante dans plusieurs cancers, incluant le cancer du…”
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