Search Results - "Harper, Jane"

Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells by Cameron, Brian J, Gerry, Andrew B, Dukes, Joseph, Harper, Jane V, Kannan, Vivekanandan, Bianchi, Frayne C, Grand, Francis, Brewer, Joanna E, Gupta, Minnal, Plesa, Gabriela, Bossi, Giovanna, Vuidepot, Annelise, Powlesland, Alex S, Legg, Alison, Adams, Katherine J, Bennett, Alan D, Pumphrey, Nicholas J, Williams, Daniel D, Binder-Scholl, Gwendolyn, Kulikovskaya, Irina, Levine, Bruce L, Riley, James L, Varela-Rohena, Angel, Stadtmauer, Edward A, Rapoport, Aaron P, Linette, Gerald P, June, Carl H, Hassan, Namir J, Kalos, Michael, Jakobsen, Bent K

“…MAGE A3, which belongs to the family of cancer-testis antigens, is an attractive target for adoptive therapy given its reactivation in various tumors and…”
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The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage by Reynolds, Pamela, Anderson, Jennifer A, Harper, Jane V, Hill, Mark A, Botchway, Stanley W, Parker, Anthony W, O'Neill, Peter

“…DNA double-strand breaks (DSBs) are biologically one of the most important cellular lesions and possess varying degrees of chemical complexity. The notion that…”
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Monoclonal TCR-redirected tumor cell killing by Liddy, Nathaniel, Bossi, Giovanna, Adams, Katherine J, Lissina, Anna, Mahon, Tara M, Hassan, Namir J, Gavarret, Jessie, Bianchi, Frayne C, Pumphrey, Nicholas J, Ladell, Kristin, Gostick, Emma, Sewell, Andrew K, Lissin, Nikolai M, Harwood, Naomi E, Molloy, Peter E, Li, Yi, Cameron, Brian J, Sami, Malkit, Baston, Emma E, Todorov, Penio T, Paston, Samantha J, Dennis, Rebecca E, Harper, Jane V, Dunn, Steve M, Ashfield, Rebecca, Johnson, Andy, McGrath, Yvonne, Plesa, Gabriela, June, Carl H, Kalos, Michael, Price, David A, Vuidepot, Annelise, Williams, Daniel D, Sutton, Deborah H, Jakobsen, Bent K

“…T cell receptor (TCR)-based immunotherapeutic approaches have so far had limited success because of a lack of specific immune recognition and activation by the…”
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Synchronization of cell populations in G1/S and G2/M phases of the cell cycle by Harper, Jane V

“…The method described in the following chapter utilizes a double thymidine block (an inhibitor of DNA synthesis) followed by treatment of cells with nocodazole…”
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An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules by Harper, Jane, Adams, Katherine J, Bossi, Giovanna, Wright, Debbie E, Stacey, Andrea R, Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S, Donnellan, Zoe, Carreira, Ricardo J, Paston, Samantha J, Weigand, Luise U, Canestraro, Martina, Sanderson, Joseph P, Botta Gordon-Smith, Sophie, Lowe, Kate L, Rygiel, Karolina A, Powlesland, Alex S, Vuidepot, Annelise, Hassan, Namir J, Cameron, Brian J, Jakobsen, Bent K, Dukes, Joseph

“…Robust preclinical testing is essential to predict clinical safety and efficacy and provide data to determine safe dose for first-in-man studies. There are a…”
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Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor by van den Berg, Joost H, Gomez-Eerland, Raquel, van de Wiel, Bart, Hulshoff, Lenie, van den Broek, Daan, Bins, Adriaan, Tan, Hanno L, Harper, Jane V, Hassan, Namir J, Jakobsen, Bent K, Jorritsma, Annelies, Blank, Christian U, Schumacher, Ton N M, Haanen, John B A G

“…Here, we describe a fatal serious adverse event observed in a patient infused with autologous T-cell receptor (TCR) transduced T cells. This TCR, originally…”
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Radiation induced DNA DSBs: Contribution from stalled replication forks? by Harper, Jane V., Anderson, Jennifer A., O’Neill, Peter

“…When cells are exposed to radiation serious lesions are introduced into the DNA including double strand breaks (DSBs), single strand breaks (SSBs), base…”
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Clonal Dissemination of Enterobacter cloacae Harboring blaKPC-3 in the Upper Midwestern United States by Hargreaves, Melissa L, Shaw, Kristin M, Dobbins, Ginette, Snippes Vagnone, Paula M, Harper, Jane E, Boxrud, Dave, Lynfield, Ruth, Aziz, Maliha, Price, Lance B, Silverstein, Kevin A T, Danzeisen, Jessica L, Youmans, Bonnie, Case, Kyle, Sreevatsan, Srinand, Johnson, Timothy J

“…Carbapenemase-producing, carbapenem-resistant Enterobacteriaceae, or CP-CRE, are an emerging threat to human and animal health, because they are resistant to…”
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Biochemical Kinetics Model of DSB Repair and Induction of γ-H2AX Foci by Non-homologous End Joining by Cucinotta, Francis A., Pluth, Janice M., Anderson, Jennifer A., Harper, Jane V., O'Neill, Peter

“…Cucinotta, F. A., Pluth, J. M., Anderson, J. A., Harper, J. V. and O'Neill, P. Biochemical Kinetics Model of DSB Repair and Induction of γ-H2AX Foci by…”
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Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity by Prevo, Remko, Deutsch, Eric, Sampson, Oliver, Diplexcito, Julie, Cengel, Keith, Harper, Jane, O'Neill, Peter, McKenna, W Gillies, Patel, Sonal, Bernhard, Eric J

“…Cell signaling initiated at the epidermal growth factor receptor (EGFR), RAS oncoproteins, or PI3K contributes to a common pathway that promotes tumor survival…”
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Participation of DNA-PKcs in DSB Repair after Exposure to High- and Low-LET Radiation by Anderson, Jennifer A., Harper, Jane V., Cucinotta, Francis A., O'Neill, Peter

“…Cellular lesions (e.g. DSBs) are induced into DNA upon exposure to radiation, with DSB complexity increasing with radiation ionization density. Using M059K and…”
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Induction and quantification of γ-H2AX foci following low and high LET-irradiation by Leatherbarrow, Emma L., Harper, Jane V., Cucinotta, Francis A., O'Neill, Peter

“…Purpose: To investigate quantitatively the induction and rejoining of DNA double strand breaks (DSB) in V79-4 and xrs-5 Chinese hamster cells and HF19 human…”
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The mammalian cell cycle: an overview by Harper, Jane V, Brooks, Gavin

“…In recent years, we have witnessed major advances in our understanding of the mammalian cell cycle and how it is regulated. Normal mammalian cellular…”
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Establishing Surveillance for Carbapenem-Resistant Enterobacteriaceae in Minnesota, 2012 by Shaw, Kristin M., Harper, Jane E., Vagnone, Paula Snippes, Lynfield, Ruth

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Thirty-Day Laboratory-Based Surveillance for Carbapenem-Resistant Enterobacteriaceae in the Minneapolis-St. Paul Metropolitan Area by Pereira, Edwin C., Shaw, Kristin M., Snippes Vagnone, Paula M., Harper, Jane E., Kallen, Alexander J., Limbago, Brandi M., Lynfield, Ruth

“…Carbapenem-resistant Enterobacteriaceae (CRE) are a growing problem in the United States. We explored the feasibility of active laboratory-based surveillance…”
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Induction of Persistent Double Strand Breaks Following Multiphoton Irradiation of Cycling and G1-arrested Mammalian Cells-Replication-induced Double Strand Breaks by Harper, Jane V., Reynolds, Pamela, Leatherbarrow, Emma L., Botchway, Stanley W., Parker, Anthony W., O'Neill, Peter

“…DNA double strand breaks (DSBs) are amongst the most deleterious lesions induced within the cell following exposure to ionizing radiation. Mammalian cells…”
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Invasive group B streptococcal disease in the elderly, Minnesota, USA, 2003-2007 by Kothari, Neelay J, Morin, Craig A, Glennen, Anita, Jackson, Delois, Harper, Jane, Schrag, Stephanie J, Lynfield, Ruth

“…In Minnesota, incidence of invasive group B streptococcal disease was 3 times greater in older adults in long-term care facilities than in older adults in…”
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Reported Endoscope Reprocessing Breaches, Minnesota, 2010-2011 by Harper, Jane, BSN, MS, CIC, DeVries, Aaron, MD, MPH, Danila, Richard, PhD, MPH, Lesher, Lindsey, MPH

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Antibiotic and Infection Tracking in Minnesota Long-Term Care Facilities by O'Fallon, Erin, Harper, Jane, Shaw, Shelly, Lynfield, Ruth

“…OBJECTIVES: To describe current systems used to track infections, antibiotic use, and antibiotic‐resistant infections in Minnesota long‐term care facilities…”
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Airway management complications during anaesthesia, in intensive care units and in emergency departments in the UK by Woodall, Nicholas M, Benger, Jonathan R, Harper, Jane S, Cook, Tim M

“…Summary In 2011 the Royal College of Anaesthetists and the Difficult Airway Society published their joint report, the Fourth National Audit Project (NAP4)…”
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