Search Results - "Harper, C C"
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1
The Neuropathology of Alcohol-Related Brain Damage
Published in Alcohol and alcoholism (Oxford) (01-03-2009)“…Excessive alcohol use can cause structural and functional abnormalities of the brain and this has significant health, social and economic implications for most…”
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2
Delivering CRISPR: a review of the challenges and approaches
Published in Drug delivery (2018)“…Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic…”
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3
The end of donor anonymity: how genetic testing is likely to drive anonymous gamete donation out of business
Published in Human reproduction (Oxford) (01-06-2016)“…Abstract Thousands of people worldwide have been conceived using donor gametes, but not all parents tell their children of their origin. Several countries now…”
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4
Spontaneous Resolution of a Combined Hamartoma in a One-Year-Old Child
Published in Ophthalmic surgery, lasers & imaging retina (01-08-2024)“…The combined hamartoma of the retina and the retinal pigment epithelium (CHR-RPE) is a rare but histologically benign tumor of which no clear consensus exists…”
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5
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling
Published in PloS one (25-05-2017)“…The use of gene expression signatures to classify compounds, identify efficacy or toxicity, and differentiate close analogs relies on the sensitivity of the…”
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Thiamine (vitamin B1) deficiency and associated brain damage is still common throughout the world and prevention is simple and safe
Published in European journal of neurology (01-10-2006)“…Many different population groups throughout the world have thiamine deficiency and are at risk of developing severe neurological and cardiac disorders…”
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Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions
Published in Science (American Association for the Advancement of Science) (13-01-2017)“…Carbohydrates are involved in nearly all aspects of biochemistry, but their complex chemical structures present long-standing practical challenges to their…”
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8
Three-Dimensional Correlation of Steric and Electronic Free Energy Relationships Guides Asymmetric Propargylation
Published in Science (American Association for the Advancement of Science) (30-09-2011)“…Chemical reaction outcomes are often rationalized on the basis of independent analyses of steric and electronic effects. We applied three-dimensional free…”
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9
A pan-genomic approach to genome databases using maize as a model system
Published in BMC plant biology (20-08-2021)“…Research in the past decade has demonstrated that a single reference genome is not representative of a species’ diversity. MaizeGDB introduces a pan-genomic…”
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10
Multidimensional steric parameters in the analysis of asymmetric catalytic reactions
Published in Nature chemistry (18-03-2012)“…Although asymmetric catalysis is universally dependent on spatial interactions to impart specific chirality on a given substrate, examination of steric effects…”
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11
Chemoselective (Hetero)Arene Electroreduction Enabled by Rapid Alternating Polarity
Published in Journal of the American Chemical Society (06-04-2022)“…Conventional chemical and even electrochemical Birch-type reductions suffer from a lack of chemoselectivity due to a reliance on alkali metals or harshly…”
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12
MaizeGDB 2018: the maize multi-genome genetics and genomics database
Published in Nucleic acids research (08-01-2019)“…Abstract Since its 2015 update, MaizeGDB, the Maize Genetics and Genomics database, has expanded to support the sequenced genomes of many maize inbred lines in…”
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13
A Porous Organic Polymer Nanotrap for Efficient Extraction of Palladium
Published in Angewandte Chemie International Edition (26-10-2020)“…To offset the environmental impact of platinum‐group element (PGE) mining, recycling techniques are being explored. Porous organic polymers (POPs) have shown…”
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14
Preimplantation genetic diagnosis: State of the ART 2011
Published in Human genetics (01-02-2012)“…For the last 20 years, preimplantation genetic diagnosis (PGD) has been mostly performed on cleavage stage embryos after the biopsy of 1–2 cells and PCR and…”
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15
Bilateral Combined Rhegmatogenous and Tractional Retinal Detachments Due to Persistent High-Titer Syphilis
Published in Ophthalmic surgery, lasers & imaging retina (01-01-2024)“…A 23-year-old man developed bilateral rhegmatogenous retinal detachments secondary to high-titer ocular syphilis. The patient's titer increased four-fold after…”
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Paradoxical thinning of the diaphragm on ultrasound is a risk factor for requiring non‐invasive ventilation in patients with neuromuscular diaphragmatic dysfunction
Published in Muscle & nerve (01-09-2024)“…Introduction/Aims Point‐of‐care ultrasound of the diaphragm is highly sensitive and specific in the detection of neuromuscular diaphragmatic dysfunction. In…”
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17
De novo choroidal osteoma after laser photocoagulation of a peripapillary choroidal neovascular membrane
Published in Oman journal of ophthalmology (01-01-2023)“…We describe the case of a 76-year-old man who developed an asymptomatic choroidal osteoma in the left eye 10 years after receiving retinal laser…”
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18
Using Physical Organic Parameters To Correlate Asymmetric Catalyst Performance
Published in Journal of organic chemistry (05-04-2013)“…A classic strategy of physical organic chemists is to probe reaction mechanisms using linear free energy relationships. Identifying such relationships in…”
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Local receptor revision and class switching to IgE in chronic rhinosinusitis with nasal polyps
Published in Allergy (Copenhagen) (01-01-2013)“…Background Chronic rhinosinusitis with nasal polyps (NP) and allergic rhinitis (AR) is characterized by local Th2 inflammation and up‐regulation of IgE;…”
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Guidelines of care for the management of acne vulgaris
Published in Journal of the American Academy of Dermatology (01-05-2016)“…Acne is one of the most common disorders treated by dermatologists and other health care providers. While it most often affects adolescents, it is not uncommon…”
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