Search Results - "Haro, Isabel"
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Implications of Post-Translational Modifications in Autoimmunity with Emphasis on Citrullination, Homocitrullination and Acetylation for the Pathogenesis, Diagnosis and Prognosis of Rheumatoid Arthritis
Published in International journal of molecular sciences (13-12-2022)“…Post-translational modifications (PTMs) influence cellular processes and consequently, their dysregulation is related to the etiologies of numerous diseases…”
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Nanotechnology-Based Platforms for Vaginal Delivery of Peptide Microbicides
Published in Current medicinal chemistry (01-01-2021)“…Vaginal drug delivery offers an opportunity for effective microbicide treatments. However, the physiological characteristics of the vagina represent a…”
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Global connections with some genomic differentiation occur between Indo‐Pacific and Atlantic Ocean wahoo, a large circumtropical pelagic fish
Published in Journal of biogeography (01-08-2021)“…Aim Globally distributed pelagic fishes are typified by very low to negligible genetic differentiation at oceanic scales arising from high gene flow and (or)…”
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Peptides Bearing Multiple Post-Translational Modifications as Antigenic Targets for Severe Rheumatoid Arthritis Patients
Published in International journal of molecular sciences (10-12-2021)“…Rheumatoid arthritis (RA) is characterized by the presence of autoantibodies that are of paramount importance for the diagnosis and prognosis of the disease…”
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Novel Chimeric Peptides Based on the Enolase Peptide Antigen (CEP-1) Bearing Three Post-Translational Modifications (Citrullination, Homocitrullination and Acetylation) for Determining the Diagnosis and Severity of Rheumatoid Arthritis
Published in International journal of molecular sciences (03-10-2024)“…With the aim of improving the uncertainties associated with the correct diagnosis of seronegative rheumatoid arthritis (RA) and identifying those at risk of…”
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Updating the use of synthetic peptides as inhibitors of HIV-1 entry
Published in Current medicinal chemistry (01-04-2014)“…The use of synthetic peptides as HIV-1 inhibitors has been the object of research over recent years. A large number of peptides that affect different stages of…”
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Development of a multiplex assay based on chimeric citrullinated peptides as proof of concept for diagnosis of rheumatoid arthritis
Published in PloS one (02-05-2019)“…Anti-citrullinated peptide/protein antibodies (ACPAs) are the most specific serological biomarkers for rheumatoid arthritis (RA). They have both diagnostic and…”
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Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
Published in Arthritis research & therapy (05-10-2023)“…Abstract Background Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA)…”
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Development of Peptide Targeted PLGA-PEGylated Nanoparticles Loading Licochalcone-A for Ocular Inflammation
Published in Pharmaceutics (26-01-2022)“…Licochalcone-A is a natural compound with anti-inflammatory properties. However, it possesses low water solubility, making its application for the treatment of…”
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Interaction of Antimicrobial Arginine-Based Cationic Surfactants with Liposomes and Lipid Monolayers
Published in Langmuir (13-04-2004)“…The present work examines the relationship between the antimicrobial activity of novel arginine-based cationic surfactants and the physicochemical process…”
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Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant
Published in PloS one (19-12-2018)“…Preventive HIV-1 vaccine strategies rely on the elicitation of broadly neutralizing antibody (bNAb) responses, but their induction in vivo by vaccination…”
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12
Force Control of a Haptic Flexible-Link Antenna Based on a Lumped-Mass Model
Published in Biomimetics (Basel, Switzerland) (07-07-2024)“…Haptic organs are common in nature and help animals to navigate environments where vision is not possible. Insects often use slender, lightweight, and flexible…”
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Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell-Penetrating Peptide
Published in Molecular therapy. Nucleic acids (06-09-2019)“…Autosomal dominantly inherited genetic disorders such as corneal dystrophies are amenable to allele-specific gene silencing with small interfering RNA (siRNA)…”
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Fractional-Order Models of Damping Phenomena in a Flexible Sensing Antenna Used for Haptic Robot Navigation
Published in Fractal and fractional (01-08-2023)“…In this paper, two types of fractional-order damping are proposed for a single flexible link: internal and external friction, related to the material of the…”
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Lipid Vesicles Loaded with an HIV-1 Fusion Inhibitor Peptide as a Potential Microbicide
Published in Pharmaceutics (31-05-2020)“…The effective use of fusion inhibitor peptides against cervical and colorectal infections requires the development of sustained release formulations. In this…”
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Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy
Published in BMC musculoskeletal disorders (21-04-2021)“…Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50-60% of rheumatoid arthritis (RA) patients. However, there are…”
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Differing specificities and isotypes of anti-citrullinated peptide/protein antibodies in palindromic rheumatism and rheumatoid arthritis
Published in Arthritis research & therapy (15-06-2017)“…To analyze differences in the recognition of anti-citrullinated peptide/protein antibody (ACPA) citrullinated epitopes and isotypes in patients with…”
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Lipid raft-like liposomes used for targeted delivery of a chimeric entry-inhibitor peptide with anti-HIV-1 activity
Published in Nanomedicine (01-02-2017)“…Abstract The work reports the design and synthesis of a chimeric peptide that is composed of the peptide sequences of two entry inhibitors which target…”
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Citrullinated peptides in the diagnosis of rheumatoid arthritis
Published in Current topics in medicinal chemistry (01-03-2013)“…Antibodies directed against citrullinated proteins and peptides (ACPAs) are the most specific serological markers available for diagnosing rheumatoid arthritis…”
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Palindromic Rheumatism: Just a Pre-rheumatoid Stage or Something Else?
Published in Frontiers in medicine (25-03-2021)“…Palindromic rheumatism (PR), a unique clinical entity, has a characteristic clinical presentation with a relapsing/remitting course. It is established that…”
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