Aerosol‐phase activity of iodine captured from a triiodide resin filter on fine particles containing an infectious virus

Aerosol‐phase activity of iodine captured from a triiodide resin filter on fine particles containing an infectious virus

AIMS: To avoid interference by water–iodine disinfection chemistry and measure directly the effect of iodine, captured from a triiodide complex bound to a filter medium, on viability of penetrating viral particles. METHODS AND RESULTS: Aerosols of MS2 coli phage were passed through control P100 or i...

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Bibliographic Details
Published in:Journal of applied microbiology Vol. 118; no. 6; pp. 1315 - 1320
Main Authors: Heimbuch, B.K, Harnish, D.A, Balzli, C, Lumley, A, Kinney, K, Wander, J.D
Format: Journal Article
Language:English
Published: England Published for the Society for Applied Bacteriology by Blackwell Science 01-06-2015
Oxford University Press
Subjects:
Aerosols
Aerosols - chemistry
Aerosols - pharmacology
air
Air Microbiology
airborne transmission
anti-infective properties
antimicrobials
bacteriophages
breathing
contact‐release mechanism
disinfection
Disinfection - instrumentation
Disinfection - methods
Half-Life
Humidity
Infections
Iodides - chemistry
iodine
Iodine - chemistry
Iodine - pharmacology
Levivirus - drug effects
Levivirus - growth & development
Microbiology
MS2 coli phage
plastic bags
Quaternary Ammonium Compounds - chemistry
Resins
respiratory protection
viability
viruses
contact-release mechanism
viruses
iodine
MS2 coli phage
antimicrobials
respiratory protection
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Summary:AIMS: To avoid interference by water–iodine disinfection chemistry and measure directly the effect of iodine, captured from a triiodide complex bound to a filter medium, on viability of penetrating viral particles. METHODS AND RESULTS: Aerosols of MS2 coli phage were passed through control P100 or iodinated High‐Efficiency Particulate Air media, collected in plastic bags, incubated for 0–10 min, collected in an impinger containing thiosulphate to consume all unreacted iodine, plated and enumerated. Comparison of viable counts demonstrated antimicrobial activity with an apparent half‐life for devitalization in tens of seconds; rate of kill decreased at low humidity and free iodine was captured by the bags. CONCLUSIONS: The results support the mechanism of near‐contact capture earlier proposed; however, the disinfection chemistry in the aerosol phase is very slow on the time scale of inhalation. SIGNIFICANCE AND IMPACT OF THE STUDY: This study shows that disinfection by filter‐bound iodine in the aerosol phase is too slow to be clinically significant in individual respiratory protection, but that it might be of benefit to limit airborne transmission of infections in enclosed areas.
Bibliography:http://dx.doi.org/10.1111/jam.12788
ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1364-5072
1365-2672
DOI:10.1111/jam.12788