Search Results - "Harms, J M"

An agenda for research and action toward diverse and just futures for life on Earth by Wyborn, C., Montana, J., Kalas, N., Clement, S., Davila, F., Knowles, N., Louder, E., Balan, M., Chambers, J., Christel, L., Forsyth, T., Henderson, G., Izquierdo Tort, S., Lim, M., Martinez‐Harms, M. J., Merçon, J., Nuesiri, E., Pereira, L., Pilbeam, V., Turnhout, E., Wood, S., Ryan, M.

“…Decades of research and policy interventions on biodiversity have insufficiently addressed the dual issues of biodiversity degradation and social justice. New…”
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Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce by Li, Qian, Hagberg, Carolina E., Silva Cascales, Helena, Lang, Shuai, Hyvönen, Mervi T., Salehzadeh, Firoozeh, Chen, Ping, Alexandersson, Ida, Terezaki, Eleni, Harms, Matthew J., Kutschke, Maria, Arifen, Nahida, Krämer, Niels, Aouadi, Myriam, Knibbe, Carole, Boucher, Jeremie, Thorell, Anders, Spalding, Kirsty L.

“…Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in…”
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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes by Harms, Matthew J., Li, Qian, Lee, Sunjae, Zhang, Cheng, Kull, Bengt, Hallen, Stefan, Thorell, Anders, Alexandersson, Ida, Hagberg, Carolina E., Peng, Xiao-Rong, Mardinoglu, Adil, Spalding, Kirsty L., Boucher, Jeremie

“…White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but there is a paucity of translational models to study mature…”
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Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity by Hagberg, Carolina E., Li, Qian, Kutschke, Maria, Bhowmick, Debajit, Kiss, Endre, Shabalina, Irina G., Harms, Matthew J., Shilkova, Olga, Kozina, Viviana, Nedergaard, Jan, Boucher, Jeremie, Thorell, Anders, Spalding, Kirsty L.

“…Adipocytes, once considered simple lipid-storing cells, are rapidly emerging as complex cells with many biologically diverse functions. A powerful…”
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Modelling pollination maps in agroecosystems of a Chilean biodiversity hotspot by U. Lavín, M. J. Martinez-Harms, J. L Celis-Diez, J. P Francois, Y. Aguirre, J. Martínez-Harms

“…Wild pollinators play a crucial role in maintaining healthy ecosystems and sustaining agricultural productivity. However, their survival is at risk due to…”
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X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit by Wilson, Daniel N, Schluenzen, Frank, Harms, Joerg M, Yoshida, Takuya, Ohkubo, Tadayasu, Albrecht, Renate, Buerger, Joerg, Kobayashi, Yuji, Fucini, Paola

“…This study presents the crystal structure of domain I of the Escherichia coli ribosome recycling factor (RRF) bound to the Deinococcus radiodurans 50S subunit…”
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Copper absorption as affected by supplemental calcium, magnesium, manganese, selenium and potassium by Kies, C, Harms, J M

“…Effects of feeding supplements of calcium, magnesium, manganese, selenium and potassium on dietary copper bioavailability of humans were investigated. Results…”
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The acute mesenteric ischemia - not understood or incurable? by Luther, B, Moussazadeh, K, Müller, B T, Franke, C, Harms, J M, Ernst, S, Sandmann, W

“…Despite surgical research and progress, the high mortality of acute intestinal ischemia seems to be improved insignificantly over the past fifty years. In this…”
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In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects by Osinski, Victoria, Bauknight, Dustin K, Dasa, Siva Sai Krishna, Harms, Matthew J, Kroon, Tobias, Marshall, Melissa A, Garmey, James C, Nguyen, Anh T, Hartman, Julia, Upadhye, Aditi, Srikakulapu, Prasad, Zhou, Andrea, O'Mahony, Gavin, Klibanov, Alexander L, Kelly, Kimberly A, Boucher, Jeremie, McNamara, Coleen A

“…Macrophages are important regulators of obesity-associated inflammation and PPARα and -γ agonism in macrophages has anti-inflammatory effects. In this study,…”
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Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin by Schlünzen, Frank, Pyetan, Erez, Fucini, Paola, Yonath, Ada, Harms, Jörg M.

“…Summary Tiamulin, a prominent member of the pleuromutilin class of antibiotics, is a potent inhibitor of protein synthesis in bacteria. Up to now the effect of…”
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Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation by Diaconu, Mihaela, Kothe, Ute, Schlünzen, Frank, Fischer, Niels, Harms, Jörg M., Tonevitsky, Alexander G., Stark, Holger, Rodnina, Marina V., Wahl, Markus C.

“…The L7/12 stalk of the large subunit of bacterial ribosomes encompasses protein L10 and multiple copies of L7/12. We present crystal structures of Thermotoga…”
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Structural Basis for the Antibiotic Activity of Ketolides and Azalides by Schlünzen, Frank, Harms, Jörg M, Franceschi, Francois, Hansen, Harly A.S, Bartels, Heike, Zarivach, Raz, Yonath, Ada

“…The azalide azithromycin and the ketolide ABT-773, which were derived by chemical modifications of erythromycin, exhibit elevated activity against a number of…”
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Species-specific antibiotic-ribosome interactions: implications for drug development by Wilson, Daniel N, Harms, Jörg M, Nierhaus, Knud H, Schlünzen, Frank, Fucini, Paola

“…In the cell, the protein synthetic machinery is a highly complex apparatus that offers many potential sites for functional interference and therefore…”
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The Binding Mode of the Trigger Factor on the Ribosome: Implications for Protein Folding and SRP Interaction by Schlünzen, Frank, Wilson, Daniel N., Tian, Pingsheng, Harms, Jörg M., McInnes, Stuart J., Hansen, Harly A.S., Albrecht, Renate, Buerger, Jörg, Wilbanks, Sigurd M., Fucini, Paola

“…This study presents the X-ray structure of the N-terminal binding domain of the D. radiodurans trigger factor (TF) in complex with the D. radiodurans large…”
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Angeborene beidseitige Zwerchfellhernie bei einem polytraumatisierten Patienten by HARMS, J. M, BÖHNER, H, WENSERSKI, F, RÖHRBORN, A, MÜLLER, E, GORETZKI, P. E

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Ecosystem value in the Western Patagonia protected areas by Martínez-Harms, María José, Gajardo, Rodolfo

“…To ensure the long-term conservation of the natural ecosystems heterogeneity in Western Patagonia, effective techniques are required for evaluating, planning…”
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The pK sub(a) Values of Acidic and Basic Residues Buried at the Same Internal Location in a Protein Are Governed by Different Factors by Harms, MJ, Castaneda, CA, Schlessman, J L, Sue, G R, Isom, D G, Cannon, B R, Garcia-Moreno E, B

“…The pK sub(a) values of internal ionizable groups are usually very different from the normal pK sub(a) values of ionizable groups in water. To examine the…”
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Antibiotics acting on the translational machinery by Harms, Jörg M, Bartels, Heike, Schlünzen, Frank, Yonath, Ada

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Controlling Spin Ordering in Canted Magnets via Heteroepitaxy by Iwata-Harms, J. M., Wong, F. J., Alaan, U. S., Kirby, B. J., Borchers, J. A., Toney, M. F., Nelson-Cheeseman, B. B., Liberati, M., Arenholz, E., Suzuki, Y.

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Laser light‐scattering evidence for an altered association of βB1‐crystallin deamidated in the connecting peptide by Harms, Michael J., Wilmarth, Philip A., Kapfer, Deborah M., Steel, Eric A., David, Larry L., Bächinger, Hans Peter, Lampi, Kirsten J.

“…Deamidation is a prevalent modification of crystallin proteins in the vertebrate lens. The effect of specific sites of deamidation on crystallin stability in…”
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