Search Results - "Harmon, Anne W"

Molecular Mechanisms of the Diabetogenic Effects of Arsenic: Inhibition of Insulin Signaling by Arsenite and Methylarsonous Acid by David S. Paul, Anne W. Harmon, Vicenta Devesa, Thomas, David J., Styblo, Miroslav

“…Increased prevalences of diabetes mellitus have been reported among individuals chronically exposed to inorganic arsenic (iAs). However, the mechanisms…”
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Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: a mechanism for impaired cellular proliferation by HARMON, Anne W, PATEL, Yashomati M

“…Certain flavonoids inhibit glucose uptake in cultured cells. In this report, we show that the grapefruit flava-none naringenin inhibited insulin-stimulated…”
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Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis by Harmon, A W, Harp, J B

“…Flavonoids, polyphenolic compounds that exist widely in plants, inhibit cell proliferation and increase cell differentiation in many cancerous and noncancerous…”
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Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase by Drobná, Zuzana, Waters, Stephen B., Devesa, Vicenta, Harmon, Anne W., Thomas, David J., Stýblo, Miroslav

“…The enzymatic methylation of inorganic As (iAs) is catalyzed by As(+3 oxidation state)-methyltransferase (AS3MT). AS3MT is expressed in rat liver and in human…”
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Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes by Paul, David S, Harmon, Anne W, Winston, Courtney P, Patel, Yashomati M

“…Calpains are a family of non-lysosomal cysteine proteases. Recent studies have identified a member of the calpain family of proteases, calpain 10, as a…”
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MEK inhibitors impair insulin-stimulated glucose uptake in 3T3-L1 adipocytes by Harmon, Anne W, Paul, David S, Patel, Yashomati M

“…In 3T3-L1 adipocytes, insulin activates three major signaling cascades, the phosphoinositide 3-kinase (PI3K) pathway, the Cbl pathway, and the…”
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Interspecies differences in metabolism of arsenic by cultured primary hepatocytes by Drobná, Zuzana, Walton, Felecia S., Harmon, Anne W., Thomas, David J., Stýblo, Miroslav

“…Biomethylation is the major pathway for the metabolism of inorganic arsenic (iAs) in many mammalian species, including the human. However, significant…”
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Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes by Walton, Felecia S, Harmon, Anne W, Paul, David S, Drobná, Zuzana, Patel, Yashomati M, Styblo, Miroslav

“…Chronic exposures to inorganic arsenic (iAs) have been associated with increased incidence of noninsulin (type-2)-dependent diabetes mellitus. Although…”
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Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes by Harmon, Anne W, Patel, Yashomati M

“…Previous studies have shown that flavonoids inhibit glucose uptake in cultured cells. In this report, we show that the grapefruit flavanone naringenin…”
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Genistein inhibits CCAAT/enhancer-binding protein beta (C/EBPbeta) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression by Harmon, Anne W, Patel, Yashomati M, Harp, Joyce B

“…The tyrosine kinase inhibitor genistein inhibits 3T3-L1 adipogenesis when present during the first 72 h of differentiation. In this report, we investigated the…”
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Activation of superoxide dismutase in selenium-deficient mice infected with influenza virus by Stýblo, Miroslav, Walton, Felecia S., Harmon, Anne W., Sheridan, Patricia A., Beck, Melinda A.

“…Selenium (Se) deficiency is associated with decreased activities of Se-dependent antioxidant enzymes, glutathione peroxidase (GPx) and thioredoxin reductase…”
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Influenza infection disrupts glucose uptake in 3T3‐L1 adipocytes by Harmon, Anne W., Beck, Melinda A.

“…Lipid rafts function as platforms for the entry, assembly, and budding of influenza virus. Because adipocytes have an abundance of lipid rafts, we questioned…”
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Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis by Cole, Kathryn A, Harmon, Anne W, Harp, Joyce B, Patel, Yashomati M

“…Two pathways are initiated upon 3T3-L1 preadipocyte differentiation: the reentry of cells into the cell cycle and the initiation of a cascade of…”
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