Search Results - "Harmancı, Akdes S"
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Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers
Published in Journal of neuro-oncology (01-06-2023)“…Introduction Meningiomas are the most common primary intracranial tumor. Recently, various genetic classification systems for meningioma have been described…”
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A patient with a novel homozygous missense mutation in FTO and concomitant nonsense mutation in CETP
Published in Journal of human genetics (01-05-2016)“…The fat mass and obesity associated (FTO) gene has previously been associated with a variety of diseases and conditions, notably obesity, acute coronary…”
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Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features
Published in Neuro-oncology (Charlottesville, Va.) (14-03-2023)“…Abstract Background Meningiomas, the most common primary intracranial tumors, can be separated into 3 DNA methylation groups with distinct biological drivers,…”
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Predictors of postoperative seizure outcome in supratentorial meningioma
Published in Journal of neurosurgery (01-08-2022)“…Meningiomas are the most common primary intracranial tumor. Seizures are common sequelae of meningioma development. Meningioma patients with seizures can be…”
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Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses
Published in Nature medicine (01-12-2023)“…Surgery is the mainstay of treatment for meningioma, the most common primary intracranial tumor, but improvements in meningioma risk stratification are needed…”
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Aggressive human MenG C meningiomas have a molecular counterpart in canines
Published in Acta neuropathologica (01-06-2024)Get full text
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Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma
Published in Acta neuropathologica (01-04-2023)Get full text
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Racial and Socioeconomic Disparities in Patients With Meningioma: A Retrospective Cohort Study
Published in Neurosurgery (01-01-2022)“…Meningiomas are the most common intracranial neoplasms. Although genomic analysis has helped elucidate differences in survival, there is evidence that racial…”
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Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies
Published in Science advances (04-02-2022)“…One-fifth of meningiomas classified as benign by World Health Organization (WHO) histopathological grading will behave malignantly. To better diagnose these…”
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Identification of novel fusion transcripts in meningioma
Published in Journal of neuro-oncology (01-09-2020)“…Introduction Meningiomas are the most common primary intracranial tumor. Recent next generation sequencing analyses have elaborated the molecular drivers of…”
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Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution
Published in Science advances (25-10-2024)“…An important subset of meningiomas behaves aggressively and is characterized by multiple recurrences. We identify clinical, genetic, and epigenetic predictors…”
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