Search Results - "Harman, Nicola L"

Choosing important health outcomes for comparative effectiveness research: 4th annual update to a systematic review of core outcome sets for research by Gargon, Elizabeth, Gorst, Sarah L, Harman, Nicola L, Smith, Valerie, Matvienko-Sikar, Karen, Williamson, Paula R

“…The Core Outcome Measures in Effectiveness Trials (COMET) database is a publically available, searchable repository of published and ongoing core outcome set…”
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Designing and using incentives to support recruitment and retention in clinical trials: a scoping review and a checklist for design by Parkinson, Beth, Meacock, Rachel, Sutton, Matt, Fichera, Eleonora, Mills, Nicola, Shorter, Gillian W, Treweek, Shaun, Harman, Nicola L, Brown, Rebecca C H, Gillies, Katie, Bower, Peter

“…Recruitment and retention of participants are both critical for the success of trials, yet both remain significant problems. The use of incentives to target…”
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The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate by Harman, Nicola L, Bruce, Iain A, Kirkham, Jamie J, Tierney, Stephanie, Callery, Peter, O'Brien, Kevin, Bennett, Alex M D, Chorbachi, Raouf, Hall, Per N, Harding-Bell, Anne, Parfect, Victoria H, Rumsey, Nichola, Sell, Debbie, Sharma, Ravi, Williamson, Paula R

“…Approximately 75% of children with cleft palate (CP) have Otitis Media with Effusion (OME) histories. Evidence for the effective management of OME in these…”
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A patient and public involvement (PPI) toolkit for meaningful and flexible involvement in clinical trials - a work in progress by Bagley, Heather J, Short, Hannah, Harman, Nicola L, Hickey, Helen R, Gamble, Carrol L, Woolfall, Kerry, Young, Bridget, Williamson, Paula R

“…Funders of research are increasingly requiring researchers to involve patients and the public in their research. Patient and public involvement (PPI) in…”
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Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes by Harman, Nicola L, Sanz-Moreno, Adrián, Papoutsopoulou, Stamatia, Lloyd, Katie A, Ameen-Ali, Kamar E, Macleod, Malcolm, Williamson, Paula R

“…In pre-clinical research, systematic reviews have the potential to mitigate translational challenges by facilitating understanding of how pre-clinical studies…”
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The Impact of Malnutrition on the Developing Lung and Long-Term Lung Health: A Narrative Review of Global Literature by Tharumakunarajah, Ramiyya, Lee, Alice, Hawcutt, Daniel B., Harman, Nicola L., Sinha, Ian P.

“…Worldwide, over 2 billion children under the age of 5 experience stunting, wasting, or are underweight. Malnutrition contributes to 45% of all deaths in this…”
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Opening up ideas: an advent calendar for patient and public engagement in clinical trials research by Harman, Nicola L, McGiveron, Kerrie, Tudur Smith, Catrin, Williamson, Paula R, Barrington, Heather

“…The involvement of patients and the public in research is now an expectation in research with funders requesting a clear plan of involvement and engagement. In…”
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SCORE-IT (Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes): a systematic review of registered trials by Harman, Nicola L, James, Rebecca, Wilding, John, Williamson, Paula R

“…Outcomes measured in clinical trials should be meaningful to patients, healthcare professionals and researchers, yet there is heterogeneity in the outcomes…”
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Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 Diabetes (SCORE-IT): study protocol for the development of a core outcome set by Harman, Nicola L, Wilding, John, Curry, Dave, Harris, James, Logue, Jennifer, Pemberton, R John, Perreault, Leigh, Thompson, Gareth, Tunis, Sean, Williamson, Paula R

“…Type 2 diabetes is characterised by abnormal glucose metabolism, and treatment is aimed at normalising glycaemia. Outcomes measured in clinical trials should…”
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Separation of the principal HDL subclasses by iodixanol ultracentrifugation by Harman, Nicola L., Griffin, Bruce A., Davies, Ian G.

“…HDL subclasses detection, in cardiovascular risk, has been limited due to the time-consuming nature of current techniques. We have developed a time-saving and…”
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A cohort examination to establish reporting of the remit and function of Trial Steering Committees in randomised controlled trials by Conroy, Elizabeth J, Arch, Barbara, Harman, Nicola L, Lane, J Athene, Lewis, Steff C, Norrie, John, Sydes, Matthew R, Gamble, Carrol

“…The DAMOCLES project established a widely used Data Monitoring Committee (DMC) Charter for randomised controlled trials (RCTs). Typically, within the UK, the…”
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Development of a core outcome set for use in routine orthodontic clinical trials by Tsichlaki, Aliki, O'Brien, Kevin, Benson, Philip E., Marshman, Zoe, Johal, Ama, Colonio-Salazar, Fiorella B., Harman, Nicola L., Fleming, Padhraig S.

“…A diverse range of outcomes is used in orthodontic research with a focus on measuring outcomes important to clinicians and little consistency in outcome…”
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MOMENT--Management of Otitis Media with Effusion in Cleft Palate: protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey by Harman, Nicola L, Bruce, Iain A, Callery, Peter, Tierney, Stephanie, Sharif, Mohammad Owaise, O'Brien, Kevin, Williamson, Paula R

“…Cleft palate (CP) has an incidence of approximately 1 in 700. Children with CP are also susceptible to otitis media with effusion (OME), with approximately 90%…”
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Core outcome measurement instruments for use in clinical and research settings for adults with post-COVID-19 condition: an international Delphi consensus study by Gorst, Sarah L, Seylanova, Nina, Dodd, Susanna R, Harman, Nicola L, O'Hara, Margaret, Terwee, Caroline B, Williamson, Paula R, Needham, Dale M, Munblit, Daniel, Nicholson, Timothy R, Aiyegbusi, Olalekan L., Akrami, Athena, Apfelbacher, Christian, Calvert, Melanie, Chen, Jessica, Chernyawskaya, Anastasia, Fallon, Vicky, Haroon, Shamil, Hughes, Sarah E., Jaure, Allison, Kokorinia, Alisa, Michelen, Melina, Olliaro, Piero, Parr, Callum, Pokrovskaya, Alexandra, Saunders, Nile, Schmitt, Jochen, Shemilt, Ian, Sigfrid, Louise, Simpson, Frances, Sivan, Manoj, Stavropoulous, Charitini

“…Post-COVID-19 condition (also known as long COVID) is a new, complex, and poorly understood disorder. A core outcome set (COS) for post-COVID-19 condition in…”
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Development of an online resource for recruitment research in clinical trials to organise and map current literature by Kearney, Anna, Harman, Nicola L, Rosala-Hallas, Anna, Beecher, Claire, Blazeby, Jane M, Bower, Peter, Clarke, Mike, Cragg, William, Duane, Sinead, Gardner, Heidi, Healy, Patricia, Maguire, Lisa, Mills, Nicola, Rooshenas, Leila, Rowlands, Ceri, Treweek, Shaun, Vellinga, Akke, Williamson, Paula R, Gamble, Carrol

“…Background Recruiting the target number of participants within the pre-specified time frame agreed with funders remains a common challenge in the completion of…”
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Developing an online, searchable database to systematically map and organise current literature on retention research (ORRCA2) by Kearney, Anna, Ashford, Polly-Anna, Butlin, Laura, Conway, Thomas, Cragg, William J, Devane, Declan, Gardner, Heidi, Gaunt, Daisy M, Gillies, Katie, Harman, Nicola L, Hunter, Andrew, Lane, Athene J, McWilliams, Catherine, Murphy, Louise, O’Nions, Carrie, Stanhope, Edward N, Vellinga, Akke, Williamson, Paula R, Gamble, Carrol

“…Background Addressing recruitment and retention challenges in trials is a key priority for methods research, but navigating the literature is difficult and…”
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Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes (SCORE-IT): a patient and healthcare professional consensus on a core outcome set for type 2 diabetes by Harman, Nicola L, Wilding, John P H, Curry, Dave, Harris, James, Logue, Jennifer, Pemberton, R John, Perreault, Leigh, Thompson, Gareth, Tunis, Sean, Williamson, Paula R

“…ObjectivesHeterogeneity in outcomes measured across trials of glucose-lowering interventions for people with type 2 diabetes impacts on the ability to compare…”
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Otitis Media with Effusion: Experiences of Children with Cleft Palate and Their Parents by Tierney, Stephanie, O'brien, Kevin, Harman, Nicola L., Sharma, Ravi K., Madden, Colm, Callery, Peter

“…Objective To explore the views of children with cleft palate and their parents about daily life with otitis media with effusion and associated hearing loss…”
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Identifying a core outcome set for pulmonary sarcoidosis research - the Foundation for Sarcoidosis Research - Sarcoidosis Clinical OUtcomes Taskforce (SCOUT) by Harman, Nicola L, Gorst, Sarah L, Williamson, Paula R, Barnathan, Elliot S, Baughman, Robert P, Judson, Marc A, Junk, Heidi, Kampstra, Nynke A, Sullivan, Eugene J, Victorson, David E, Walton, Marc K, Al-Hakim, Tamara, Nabulsi, Hana, Singh, Noopur, Grutters, Jan C, Culver, Daniel A

“…Pulmonary sarcoidosis is a rare granulomatous disease of unknown aetiology. Heterogeneity in the outcomes measured in trials of treatment for pulmonary…”
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Incorporating patients’ perspectives into the initial stages of core outcome set development: a rapid review of qualitative studies of type 2 diabetes by Gorst, Sarah L, Young, Bridget, Williamson, Paula R, Wilding, John P H, Harman, Nicola L

“…Conducting systematic reviews of qualitative studies to incorporate patient perspectives within the early stages of core outcome set (COS) development can be…”
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