Search Results - "Harlow, Amy"

Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor by HEINRICH, Michael C, MAKI, Robert G, FLETCHER, Christopher D. M, XIN HUANG, COHEN, Darrel P, BAUM, Charles M, DEMETRI, George D, CORLESS, Christopher L, ANTONESCU, Cristina R, HARLOW, Amy, GRIFFITH, Diana, TOWN, Ajia, MCKINLEY, Arin, OU, Wen-Bin, FLETCHER, Jonathan A

“…Most gastrointestinal stromal tumors (GISTs) harbor mutant KIT or platelet-derived growth factor receptor alpha (PDGFRA) kinases, which are imatinib targets…”
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KIT Gene Mutations and Copy Number in Melanoma Subtypes by BEADLING, Carol, JACOBSON-DUNLOP, Erick, RUBIN, Brian P, MULLER, Susan, WEST, Rob, HEINRICH, Michael C, CORLESS, Christopher L, HODI, F. Stephen, LE, Claudia, WARRICK, Andrea, PATTERSON, Janice, TOWN, Ajia, HARLOW, Amy, CRUZ, Frank, AZAR, Sharl

“…Purpose: We recently identified a KIT exon 11 mutation in an anorectal melanoma of a patient who had an excellent response to treatment with imatinib. To…”
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Phase II, Open-Label Study Evaluating the Activity of Imatinib in Treating Life-Threatening Malignancies Known to Be Associated with Imatinib-Sensitive Tyrosine Kinases by Heinrich, Michael C, Joensuu, Heikki, Demetri, George D, Corless, Christopher L, Apperley, Jane, Fletcher, Jonathan A, Soulieres, Denis, Dirnhofer, Stephan, Harlow, Amy, Town, Ajia, McKinley, Arin, Supple, Shane G, Seymour, John, Di Scala, Lilla, van Oosterom, Allan, Herrmann, Richard, Nikolova, Zariana, McArthur, And Grant

“…Purpose: To evaluate the activity of imatinib in treating advanced, life-threatening malignancies expressing one or more imatinib-sensitive tyrosine kinases…”
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Risk Stratification for Ankle Fracture Complications in Diabetic Patients by Hunt, Kenneth, Moon, Daniel, Morales, Joseph, Harlow, Amy

“…Category: Diabetes Introduction/Purpose: While diabetes is a well-known risk factor for morbidity following surgical fixation of ankle fractures, it is likely…”
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Annual ADEA Survey of Dental School Seniors, 2006 Graduating Class by Chmar, Jacqueline E., Harlow, Amy H., Weaver, Richard G., Valachovic, Richard W.

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Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer by Schittenhelm, Marcus M, Kollmannsberger, Christian, Oechsle, Karin, Harlow, Amy, Morich, Jason, Honecker, Friedemann, Kurek, Raffael, Störkel, Stephan, Kanz, Lothar, Corless, Christopher L, Wong, Kwok-Kin, Bokemeyer, Carsten, Heinrich, Michael C

“…Antibodies targeting epidermal growth factor receptor (EGFR) have proven to be effective in patients with non-small cell lung cancer (NSCLC) that express EGFR…”
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Correlation of minimal residual disease cell frequency with molecular genotype in patients with acute myeloid leukemia by Hess, Corine J, Feller, Nicole, Denkers, Fedor, Kelder, Angele, Merle, Pauline A, Heinrich, Michael C, Harlow, Amy, Berkhof, Johannes, Ossenkoppele, Gert J, Waisfisz, Quinten, Schuurhuis, Gerrit J

“…1 Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands 2 Department of Pathology and Medicine, Oregon Health and Science…”
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Multiplex Mutation Screening by Mass Spectrometry by Beadling, Carol, Heinrich, Michael C, Warrick, Andrea, Forbes, Erin M, Nelson, Dylan, Justusson, Emily, Levine, Judith, Neff, Tanaya L, Patterson, Janice, Presnell, Ajia, McKinley, Arin, Winter, Laura J, Dewey, Christie, Harlow, Amy, Barney, Oscar, Druker, Brian J, Schuff, Kathryn G, Corless, Christopher L

“…There is an immediate and critical need for a rapid, broad-based genotyping method that can evaluate multiple mutations simultaneously in clinical cancer…”
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Pediatric KIT-wild-type and platelet-derived growth factor receptor α-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumors by JANEWAY, Katherine A, LIEGL, Bernadette, HARLOW, Amy, LE, Claudia, PEREZ-ATAYDE, Antonio, KOZAKEWICH, Harry, CORLESS, Christopher L, HEINRICH, Michael C, FLETCHER, Jonathan A

“…Fewer than 15% of gastrointestinal stromal tumors (GIST) in pediatric patients harbor KIT or platelet-derived growth factor receptor alpha (PDGFRA) mutations…”
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Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry by Beadling, Carol, Heinrich, Michael C, Warrick, Andrea, Forbes, Erin M, Nelson, Dylan, Justusson, Emily, Levine, Judith, Neff, Tanaya L, Patterson, Janice, Presnell, Ajia, McKinley, Arin, Winter, Laura J, Dewey, Christie, Harlow, Amy, Barney, Oscar, Druker, Brian J, Schuff, Kathryn G, Corless, Christopher L

“…There is an immediate and critical need for a rapid, broad-based genotyping method that can evaluate multiple mutations simultaneously in clinical cancer…”
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An Activating KRAS Mutation in Imatinib Resistant Chronic Myeloid Leukemia by Agarwal, Anupriya, Eide, Christopher A., Harlow, Amy, Tyner, Jeffrey W., Mauro, Michael J., Corless, Christopher L., Heinrich, Michael C., Druker, Brian J., Deininger, Michael W.

“…Background: Resistance to imatinib in patients with chronic myeloid leukemia (CML) is commonly associated with reactivation of BCR-ABL due to kinase domain…”
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In vitro profiling of the sensitivity of pediatric leukemia cells to tipifarnib: identification of T-cell ALL and FAB M5 AML as the most sensitive subsets by Goemans, Bianca F., Zwaan, Christian M., Harlow, Amy, Loonen, Anne H., Gibson, Brenda E.S., Hählen, Karel, Reinhardt, Dirk, Creutzig, Ursula, Heinrich, Michael C., Kaspers, Gertjan J.L.

“…Although the prognosis of pediatric leukemias has improved considerably, many patients still have relapses. Tipifarnib, a farnesyl transferase inhibitor (FTI),…”
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