Search Results - "Harks, Inga"
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1
Bacterial community shift in treated periodontitis patients revealed by ion torrent 16S rRNA gene amplicon sequencing
Published in PloS one (01-08-2012)“…Periodontitis, one of the most common diseases in the world, is caused by a mixture of pathogenic bacteria and inflammatory host responses and often treated by…”
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2
Impact of the Daily Use of a Microcrystal Hydroxyapatite Dentifrice on De Novo Plaque Formation and Clinical/Microbiological Parameters of Periodontal Health. A Randomized Trial
Published in PloS one (28-07-2016)“…This 12-week prospective, randomized, double-blind, two-center trial evaluated the impact of a microcrystalline zinc hydroxyapatite (mHA) dentifrice on plaque…”
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3
Is progression of periodontitis relevantly influenced by systemic antibiotics? A clinical randomized trial
Published in Journal of clinical periodontology (01-09-2015)“…Aim We investigated the long‐term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented…”
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4
Clinical benefits of systemic amoxicillin/metronidazole may depend on periodontitis severity and patients' age: An exploratory sub‐analysis of the ABPARO trial
Published in Journal of clinical periodontology (01-04-2019)“…Aim The aim was to identify benefit thresholds for clinical variables. We hypothesize, if variables fall below or exceed these threshold levels, systemic…”
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5
Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis
Published in PloS one (18-04-2018)“…Empiric antibiotics are often used in combination with mechanical debridement to treat patients suffering from periodontitis and to eliminate…”
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6
The role of the oral microbiota in the causal effect of adjunctive antibiotics on clinical outcomes in stage III-IV periodontitis patients
Published in Microbiome (26-10-2024)“…Periodontitis, a prevalent chronic inflammatory disease, offers insights into the broader landscape of chronic inflammatory conditions. The progression and…”
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7
Impact of anti‐infective periodontal therapy on parameters of vascular health
Published in Journal of clinical periodontology (01-03-2018)“…Aim This study assessed the impact of anti‐infective periodontal therapy on the status of vascular health. Materials and Methods Periodontal and vascular…”
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8
Arterial stiffness and pulse wave reflection are increased in patients suffering from severe periodontitis
Published in PloS one (01-08-2014)“…This single blind cross-sectional study compared the vascular health of subjects suffering from severe chronic periodontitis, severe aggressive periodontitis…”
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9
Validation of reported genetic risk factors for periodontitis in a large-scale replication study
Published in Journal of clinical periodontology (01-06-2013)“…Aim Many studies investigated the role of genetic variants in periodontitis, but few were established as risk factors. We aimed to validate the associations of…”
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10
Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men
Published in Journal of clinical periodontology (01-12-2014)“…Aim Periodontitis (PD) is influenced by genetic as well as lifestyle and socio‐economic factors. Epidemiological studies show that men are at greater risk of…”
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11
Significant Short-Term Shifts in the Microbiomes of Smokers With Periodontitis After Periodontal Therapy With Amoxicillin & Metronidazole as Revealed by 16S rDNA Amplicon Next Generation Sequencing
Published in Frontiers in cellular and infection microbiology (05-05-2020)“…The aim of this follow-up study was, to compare the effects of mechanical periodontal therapy with or without adjunctive amoxicillin and metronidazole on the…”
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12
Retrospective analysis of the long‐term effect of subgingival air polishing in supportive periodontal therapy
Published in Journal of clinical periodontology (01-02-2021)“…Aim Glycine powder air polishing (GPAP) procedure has become popular. Aim of the analysis was to compare the clinical outcomes during supportive periodontal…”
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13
Clinical benefits of systemic amoxicillin/metronidazole may depend on periodontitis stage and grade: An exploratory sub‐analysis of the ABPARO trial
Published in Journal of clinical periodontology (01-09-2023)“…Aim Assessment of treatment response after systemic amoxicillin/metronidazole adjunctive to subgingival instrumentation (SI) according to stages and grades of…”
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14
Long‐term changes in the subgingival microbiota in patients with stage III–IV periodontitis treated by mechanical therapy and adjunctive systemic antibiotics: A secondary analysis of a randomized controlled trial
Published in Journal of clinical periodontology (01-08-2023)“…Aim To explore whether adjunctive antibiotics can relevantly influence long‐term microbiota changes in stage III–IV periodontitis patients. Materials and…”
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15
No differences in microbiome changes between anti‐adhesive and antibacterial ingredients in toothpastes during periodontal therapy
Published in Journal of periodontal research (01-08-2019)“…Aim This subgroup analysis of a 12‐week randomized, double‐blind, and two‐center trial aimed to evaluate whether two different toothpaste formulations can…”
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16
Effect of periodontal therapy on adipokine biomarkers in overweight
Published in Journal of clinical periodontology (01-07-2020)“…Aim The aim of this study was to evaluate the effect of non‐surgical periodontal therapy on circulating levels of the systemic inflammation‐associated…”
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17
Genetic Evidence for PLASMINOGEN as a Shared Genetic Risk Factor of Coronary Artery Disease and Periodontitis
Published in Circulation. Cardiovascular genetics (01-02-2015)“…BACKGROUND—Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD)…”
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18
Is furcation involvement affected by adjunctive systemic amoxicillin plus metronidazole? A clinical trials exploratory subanalysis
Published in Journal of clinical periodontology (01-10-2016)“…Objectives Evaluation of the clinical effect of systemic amoxicillin and metronidazole adjunctively to mechanical debridement at furcation sites. Material and…”
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19
Hyaluronan-mediated mononuclear leukocyte binding to gingival fibroblasts
Published in Clinical oral investigations (01-03-2018)“…Objectives Binding of mononuclear leukocytes to hyaluronan cable structures is a well-known pathomechanism in several chronic inflammatory diseases, but has…”
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20
A large candidate-gene association study suggests genetic variants at IRF5 and PRDM1 to be associated with aggressive periodontitis
Published in Journal of clinical periodontology (01-12-2014)“…Aim Epidemiological and clinical studies indicated a relationship of periodontitis with rheumatoid arthritis (RA). We aimed to identify shared genetic…”
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