Search Results - "Harkin, Julia"

Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism by Buyco, Delfin Gerard, Dempsey, Joseph L, Scorletti, Eleonora, Jeon, Sookyoung, Lin, Chelsea, Harkin, Julia, Bayen, Susovon, Furth, Emma E, Martin, Jasmin, Delima, Monique, Hooks, Royce, Sostre-Colón, Jaimarie, Gharib, Sina A, Titchenell, Paul M, Carr, Rotonya M

“…There is significant overlap between non-alcoholic fatty liver disease (NAFLD) and alcohol-associated liver disease (ALD) with regards to risk factors and…”
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Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation by Jeon, Sookyoung, Scorletti, Eleonora, Dempsey, Joseph, Buyco, Delfin, Lin, Chelsea, Saiman, Yedidya, Bayen, Susovon, Harkin, Julia, Martin, Jasmin, Hooks, Royce, Ogretmen, Besim, Argemi, Josepmaria, Melo, Luma, Bataller, Ramon, Carr, Rotonya M.

“…Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality worldwide. Current strategies to manage ALD focus largely on advanced…”
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A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice by Scorletti, Eleonora, Saiman, Yedidya, Jeon, Sookyoung, Schneider, Carolin V., Buyco, Delfin G., Lin, Chelsea, Himes, Blanca E., Mesaros, Clementina A., Vujkovic, Marijana, Creasy, Kate Townsend, Furth, Emma E., Billheimer, Jeffrey T., Hand, Nicholas J., Kaplan, David E., Chang, Kyong-Mi, Tsao, Philip S., Lynch, Julie A., Dempsey, Joseph L., Harkin, Julia, Bayen, Susovon, Conlon, Donna, Guerraty, Marie, Phillips, Michael C., Rader, Daniel J., Carr, Rotonya M.

“…Non-alcoholic fatty liver disease (NAFLD) is characterised by the accumulation of lipid droplets (LDs) within hepatocytes. Perilipin 2 (PLIN2) is the most…”
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