Association between oral contraceptives with lipid profile: results from Hoveyzeh cohort study (HCS)

Association between oral contraceptives with lipid profile: results from Hoveyzeh cohort study (HCS)

Abstract Background Oral contraceptives (OCs) affect lipid metabolism, which can cause hyperlipidemia, a risk factor for cardiovascular diseases. The study was designed to evaluate the possible changes in lipid profile due to using OCs. Methods A cross-sectional study was conducted from April 2016 t...

Full description

Saved in:
Bibliographic Details
Published in:BMC women's health Vol. 23; no. 1; pp. 1 - 552
Main Authors: Hashemi, Seyed Jalal, Khezri, Rozhan, Saki, Nader, Nasehi, Nahal, Hosseini, Seyed Ahmad, Harizi, Mahmood, Rahimi, Zahra
Format: Journal Article
Language:English
Published: London BioMed Central Ltd 24-10-2023
BioMed Central
BMC
Subjects:
Birth control
Body mass index
Cardiovascular diseases
Cholesterol
Cohort analysis
Complications and side effects
Contraceptives
Demographic aspects
Dyslipidemia
Estrogens
Exercise
High density lipoprotein
Hyperlipidemia
Illiteracy
Iran
Lipids
Menstruation
Metabolic disorders
Oral contraceptives
Principal components analysis
Public health
Quality control
Questionnaires
Regression analysis
Risk factors
Triglycerides
Womens health
Iran
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background Oral contraceptives (OCs) affect lipid metabolism, which can cause hyperlipidemia, a risk factor for cardiovascular diseases. The study was designed to evaluate the possible changes in lipid profile due to using OCs. Methods A cross-sectional study was conducted from April 2016 to August 2018 among women from the baseline phase Hoveyzeh cohort study (HCS). Sociodemographic data, anthropometric measurements, physical activity, and biochemical blood tests were measured for every participant. Multiple logistic regression was used to adjust the potential confounders. Results Among 2272 participants, 1549 women were OC users, and 723 women were non-user OCs. The mean lipid profile levels were higher in OC users than in non-user OCs. Odds of abnormal Total cholesterol (TC) in OC users were significantly higher than those of non-users OCs [OR = 1.29 (95% CI;1.05 to 1.58)]. Also, the Odds of abnormal low-density lipoprotein (LDL) in OC users was 12% higher than in non-user OCs. However, no significant relationship between abnormal LDL with Oral Contraceptive Pills (OCPs) was observed. Conclusions The mean lipid profile was higher in OC users compared to non-user OCs. This finding highlights the need for public health strategies to prevent and detect hyperlipidemia in user OCs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1472-6874
1472-6874
DOI:10.1186/s12905-023-02703-7