Search Results - "Hariri, A"
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Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
Published in Molecular psychiatry (01-07-2013)“…Endocannabinoids are released ‘on-demand’ on the basis of physiological need, and can be pharmacologically augmented by inhibiting their catabolic degradation…”
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2
An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents
Published in Molecular psychiatry (01-02-2017)“…Identifying biological mechanisms through which the experience of adversity emerges as individual risk for mental illness is an important step toward…”
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3
Quantitative failure metric for gravity dams
Published in Earthquake engineering & structural dynamics (01-03-2015)“…SummaryQuantitative failure monitoring is a critical tool for safety assessment of concrete dams. This includes damage occurrence, intensity, location, number,…”
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4
Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity
Published in Molecular psychiatry (01-01-2009)“…Individual differences in traits such as impulsivity involve high reward sensitivity and are associated with risk for substance use disorders. The ventral…”
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5
Independent control of the thermodynamic and kinetic properties of aptamer switches
Published in Nature communications (07-11-2019)“…Molecular switches that change their conformation upon target binding offer powerful capabilities for biotechnology and synthetic biology. Aptamers are useful…”
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A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology
Published in Molecular psychiatry (01-03-2013)“…Neurogenetics research has begun to advance our understanding of how genetic variation gives rise to individual differences in brain function, which, in turn,…”
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Structural alterations within cerebellar circuitry are associated with general liability for common mental disorders
Published in Molecular psychiatry (01-04-2018)“…Accumulating mental-health research encourages a shift in focus toward transdiagnostic dimensional features that are shared across categorical disorders. In…”
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FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity
Published in Genes, brain and behavior (01-10-2012)“…FKBP5 SNPs showing significant interaction effects with emotional neglect on right dorsal amygdala reactivity. Individual variation in physiological…”
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A massively parallel screening platform for converting aptamers into molecular switches
Published in Nature communications (24-04-2023)“…Aptamer-based molecular switches that undergo a binding-induced conformational change have proven valuable for a wide range of applications, such as imaging…”
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Obstructive Sleep Apnea in Obese Patients: a UK Population Analysis
Published in Obesity surgery (01-05-2021)“…Background Obstructive sleep apnea (OSA) is an increasingly common disorder associated with increased cardiovascular disease, mortality, reduced productivity,…”
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The association between cognitive function and subsequent depression: a systematic review and meta-analysis
Published in Psychological medicine (01-01-2017)“…Despite a growing interest in understanding the cognitive deficits associated with major depressive disorder (MDD), it is largely unknown whether such deficits…”
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12
Impact of COVID-19 pandemic on head-neck cancer referral and treatment pathway in North East London
Published in Annals of the Royal College of Surgeons of England (01-08-2023)“…The COVID-19 pandemic has led to wide-ranging disruption of head-neck cancer (HNC) service provision in the UK. Early reports suggest delays in referral,…”
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13
Improved immunoassay sensitivity and specificity using single-molecule colocalization
Published in Nature communications (12-09-2022)“…Enzyme-linked immunosorbent assays (ELISAs) are a cornerstone of modern molecular detection, but the technique still faces notable challenges. One of the…”
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14
Healing patient, harming planet? A drive towards sustainable surgery: review of waste production and recyclability of surgical instrument packaging
Published in Annals of the Royal College of Surgeons of England (01-07-2024)“…Healthcare contributes more than 1% of all domestic waste in the United Kingdom (UK), with operating theatre waste alone accounting for approximately 50% of…”
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Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: possible differential markers of affective and impulsive pathways of risk for alcohol use disorder
Published in Molecular psychiatry (01-03-2016)“…Prior work suggests that there may be two distinct pathways of alcohol use disorder (AUD) risk: one associated with positive emotion enhancement and behavioral…”
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Dynamic DNA Nanotubes: Reversible Switching between Single and Double-Stranded Forms, and Effect of Base Deletions
Published in ACS nano (22-12-2015)“…DNA nanotubes hold great potential as drug delivery vehicles and as programmable templates for the organization of materials and biomolecules. Existing methods…”
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Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology
Published in Psychological medicine (01-09-2015)“…Early life stress (ELS) is consistently associated with increased risk for subsequent psychopathology. Individual differences in neural response to reward may…”
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Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression
Published in Molecular psychiatry (01-07-2008)“…Complex genetic disorders such as depression likely exhibit epistasis, but neural mechanisms of such gene–gene interactions are incompletely understood…”
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Vibration Anatomy and Damage Detection in Power Transmission Towers with Limited Sensors
Published in Sensors (Basel, Switzerland) (20-03-2020)“…This study presents a technique to identify the vibration characteristics in power transmission towers and to detect the potential structural damages. This…”
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A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivity
Published in Molecular psychiatry (01-09-2005)“…Recent studies have indicated that a newly identified second isoform of the tryptophan hydroxylase gene (TPH2) is preferentially involved in the rate-limiting…”
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