Search Results - "Haringman, Jasper"
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Workload scoring systems in the Intensive Care and their ability to quantify the need for nursing time: A systematic literature review
Published in International journal of nursing studies (01-01-2020)“…The Intensive Care Unit is a resource intense service with a high nursing workload per patient resulting in a low ratio of patients per nurse. This review aims…”
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Target attainment and pharmacokinetics of cefotaxime in critically ill patients undergoing continuous kidney replacement therapy
Published in Journal of antimicrobial chemotherapy (28-11-2022)“…Abstract Objectives Limited data exist about the antimicrobial target attainment and pharmacokinetics of cefotaxime in critically ill patients in the ICU…”
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Pharmacokinetics of zanamivir in critically ill patients undergoing continuous venovenous hemofiltration
Published in Antiviral therapy (01-02-2023)“…Limited data exist for dosing of zanamivir in the setting of CVVH in the intensive care unit (ICU). Our objective is to report the pharmacokinetics and sieving…”
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Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (13-03-2018)“…IMPORTANCE: It remains uncertain whether nebulization of mucolytics with bronchodilators should be applied for clinical indication or preventively in intensive…”
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Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models
Published in Antibiotics (Basel) (28-11-2023)“…In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target…”
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Endoscopic Clip-Assisted Feeding Tube Placement Reduces Repeat Endoscopy Rate: Results from a Randomized Controlled Trial
Published in The American journal of gastroenterology (01-08-2012)“…To determine whether endoscopic clip-assisted nasoenteral feeding tube placement is more effective than standard feeding tube placement with transnasal…”
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RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (09-05-2018)“…Evidence for benefit of high positive end-expiratory pressure (PEEP) is largely lacking for invasively ventilated, critically ill patients with uninjured…”
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Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis
Published in Arthritis research & therapy (01-01-2005)“…Analysis of biomarkers in synovial tissue is increasingly used in the evaluation of new targeted therapies for patients with rheumatoid arthritis (RA). This…”
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Chemokine blockade: a new era in the treatment of rheumatoid arthritis?
Published in Arthritis research & therapy (01-01-2004)“…Blockade of chemokines or chemokine receptors is emerging as a new potential treatment for various immune-mediated conditions. This review focuses on the…”
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The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)
Published in Arthritis research (01-01-2001)“…Paired synovial tissue samples were obtained from both clinically uninvolved (CU) and clinically involved (CI) knee joints of eight rheumatoid arthritis (RA)…”
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Synovial tissue analysis in clinical trials
Published in Journal of rheumatology (01-12-2005)“…Synovial tissue analysis has considerable potential for future randomized controlled trials (RCT). The synovial membrane is the target tissue in treatment…”
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Journal Article Conference Proceeding -
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Targeting cellular adhesion molecules, chemokines and chemokine receptors in rheumatoid arthritis
Published in Expert opinion on emerging drugs (01-05-2005)“…The development of specific targeted therapies, such as anti-TNF-alpha treatment, for chronic inflammatory disorders such as rheumatoid arthritis, has…”
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The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study
Published in Intensive care medicine (01-01-2020)“…Purpose Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but…”
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Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial
Published in Intensive care medicine (01-12-2022)“…Purpose Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an…”
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Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study
Published in The lancet respiratory medicine (01-02-2021)“…Little is known about the practice of ventilation management in patients with COVID-19. We aimed to describe the practice of ventilation management and to…”
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A randomized controlled trial with an anti‐CCL2 (anti–monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis
Published in Arthritis and rheumatism (01-08-2006)“…Objective Chemokines such as CCL2/monocyte chemotactic protein 1 (MCP‐1) play a key role in leukocyte migration and are potential targets in the treatment of…”
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Respiratory impairment in four patients associated with exposure to palytoxin containing coral
Published in Clinical toxicology (Philadelphia, Pa.) (01-02-2014)Get full text
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Effects of oral prednisolone on biomarkers in synovial tissue and clinical improvement in rheumatoid arthritis
Published in Arthritis and rheumatism (01-12-2004)“…Objective To create greater understanding of the changes in synovial tissue parameters that occur in conjunction with clinical response by using an effective…”
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