Search Results - "Haridas, Viraga"

Imaging flow cytometry analysis of intracellular pathogens by Haridas, Viraga, Ranjbar, Shahin, Vorobjev, Ivan A., Goldfeld, Anne E., Barteneva, Natasha S.

“…[Display omitted] •Imaging flow cytometry (IFC) characterize hundreds thousands of cellular images using hundreds of measurements of morphological and…”
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The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus by Jasenosky, Luke D., Cadena, Cristhian, Mire, Chad E., Borisevich, Viktoriya, Haridas, Viraga, Ranjbar, Shahin, Nambu, Aya, Bavari, Sina, Soloveva, Veronica, Sadukhan, Supriya, Cassell, Gail H., Geisbert, Thomas W., Hur, Sun, Goldfeld, Anne E.

“…Here, we show that the US Food and Drug Administration-approved oral drug nitazoxanide (NTZ) broadly amplifies the host innate immune response to viruses and…”
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A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection by Ranjbar, Shahin, Haridas, Viraga, Jasenosky, Luke D., Falvo, James V., Goldfeld, Anne E.

“…The interferon (IFN)-induced transmembrane (IFITM) proteins are critical mediators of the host antiviral response. Here, we expand the role of IFITM proteins…”
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Targeted Delivery of Small Interfering RNA to Human Dendritic Cells To Suppress Dengue Virus Infection and Associated Proinflammatory Cytokine Production by Subramanya, Sandesh, Kim, Sang-Soo, Abraham, Sojan, Yao, Jiahong, Kumar, Mukesh, Kumar, Priti, Haridas, Viraga, Lee, Sang-Kyung, Shultz, Leonard D, Greiner, Dale, N, Manjunath, Shankar, Premlata

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth by Ranjbar, Shahin, Haridas, Viraga, Nambu, Aya, Jasenosky, Luke D., Sadhukhan, Supriya, Ebert, Thomas S., Hornung, Veit, Cassell, Gail H., Falvo, James V., Goldfeld, Anne E.

“…To establish stable infection, Mycobacterium tuberculosis (MTb) must overcome host innate immune mechanisms, including those that sense pathogen-derived…”
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Concurrent generation of effector and central memory CD8 T cells during vaccinia virus infection by Laouar, Amale, Manocha, Monika, Haridas, Viraga, Manjunath, N

“…It is generally thought that during the contraction phase of an acute anti-viral T cell reponse, the effector T cells that escape activation-induced cell death…”
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Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins by Powell, Saul R., Wang, Ping, Divald, Andras, Teichberg, Saul, Haridas, Viraga, McCloskey, Thomas W., Davies, Kelvin J.A., Katzeff, Harvey

“…Cellular senescence may be accompanied by accumulation of large aggregates of oxidized proteins, also known as lipofuscin. The hypothesis that cellular…”
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Response to superantigen stimulation in peripheral blood mononuclear cells from children perinatally infected with human immunodeficiency virus and receiving highly active antiretroviral therapy by McCloskey, Thomas W, Haridas, Viraga, Pontrelli, Lucy, Pahwa, Savita

“…Our understanding of the pathogenesis of perinatal human immunodeficiency virus (HIV) infection is still evolving. We sought to characterize the response to…”
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Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells by Jasenosky, Luke D, Nambu, Aya, Tsytsykova, Alla V, Ranjbar, Shahin, Haridas, Viraga, Kruidenier, Laurens, Tough, David F, Goldfeld, Anne E

“…The human locus genes , , and are expressed in a cell type-specific manner. In this study, we show that a highly conserved NFAT binding site within the distal…”
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T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice by Kumar, Priti, Ban, Hong-Seok, Kim, Sang-Soo, Wu, Haoquan, Pearson, Todd, Greiner, Dale L., Laouar, Amale, Yao, Jiahong, Haridas, Viraga, Habiro, Katsuyoshi, Yang, Yong-Guang, Jeong, Ji-Hoon, Lee, Kuen-Yong, Kim, Yong-Hee, Kim, Sung Wan, Peipp, Matthias, Fey, Georg H., Manjunath, N., Shultz, Leonard D., Lee, Sang-Kyung, Shankar, Premlata

“…Evaluation of the therapeutic potential of RNAi for HIV infection has been hampered by the challenges of siRNA delivery and lack of suitable animal models…”
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TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB by Haridas, Viraga, Pean, Polidy, Jasenosky, Luke D, Madec, Yoann, Laureillard, Didier, Sok, Thim, Sath, Sun, Borand, Laurence, Marcy, Olivier, Chan, Sarin, Tsitsikov, Erdyni, Delfraissy, Jean-François, Blanc, François-Xavier, Goldfeld, Anne E

“…To investigate the impact of tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) upon immunological recovery and the T-cell…”
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CD70 + antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa by Manjunath, N, Laouar, Amale, Haridas, Viraga, Vargas, Dorothy, Zhinan, Xia, Chaplin, David, van Lier, Rene A W

“…One unresolved issue in gut immunity is how mucosal T lymphocytes are activated and which antigen-presenting cell (APC) is critical for the regulation of this…”
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Enhanced Induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic Cell-targeted Delivery of SOCS-1 siRNA by Subramanya, Sandesh, Armant, Myriam, Salkowitz, Janelle R, Nyakeriga, Alice M, Haridas, Viraga, Hasan, Maroof, Bansal, Anju, Goepfert, Paul A, Wynn, Katherine K, Ladell, Kristin, Price, David A, Manjunath, N, Kan-Mitchell, June, Shankar, Premlata

“…Dendritic cells (DCs) are potent antigen-presenting cells that play a critical role in the activation of T cells. RNA interference (RNAi)-mediated silencing of…”
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Cytokine response in children undergoing surgery for congenital heart disease by Madhok, Ashish B, Ojamaa, Kaie, Haridas, Viraga, Parnell, Vincent A, Pahwa, Savita, Chowdhury, D

“…Pediatric cardiac surgery with cardiopulmonary bypass (CPB) induces a complex inflammatory response that may cause multiorgan dysfunction. The objective of…”
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Discordant expression of perforin and granzyme A in total and HIV-specific CD8 T lymphocytes of HIV infected children and adolescents by HARIDAS, Viraga, MCCLOSKEY, Thomas W, PAHWA, Rajendra, PAHWA, Savita

“…Perforin and granzyme are cytotoxic effector molecules that are believed to play essential roles in cytotoxic T cell (CTL) activity. We tested the hypothesis…”
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CD70 super(+) antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa by Laouar, Amale, Haridas, Viraga, Vargas, Dorothy, Zhinan, Xia, Chaplin, David, Van Lier, Rene A W, Manjunath, N

“…One unresolved issue in gut immunity is how mucosal T lymphocytes are activated and which antigen-presenting cell (APC) is critical for the regulation of this…”
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CD70+ antigen-presenting cell controls the expansion and differentiation of T cells in the intestinal mucosa by Laouar, Amale, Haridas, Viraga, Vargas, Dorathy, Zhinan, Xia, Chaplin, David, van Lier, Rene A. W., Manjunath, N

“…One unresolved issue in gut immunity is how the mucosal T lymphocytes are activated and which antigen presenting cell (APC) is critical for regulating this…”
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T cell receptor Vβ repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children by MCCLOSKEY, Thomas W, HARIDAS, Viraga, PAHWA, Rajendra, PAHWA, Savita

“…Analysis of the T cell receptor V beta repertoire during HIV infection reveals expansions in multiple V beta families of CD8 T cells, but their antigenic…”
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Human immunodeficiency virus gag and pol‐specific CD8 T cells in perinatal HIV infection by McCloskey, Thomas W., Haridas, Viraga, Pahwa, Raj, Pahwa, Savita

“…Background: Binding of fluorochrome‐conjugated MHC class I tetramers is a powerful means to detect antigen‐specific CD8 T lymphocytes. In human…”
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