Search Results - "Haridas, A."
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Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin
Published in The journal of clinical endocrinology and metabolism (01-10-2015)“…Objective: Circulating ANGPTL8 has recently been used as a marker of insulin action. We studied expression and insulin regulation of ANGPTL8 and ANGPTL3 in…”
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Adipocyte-endothelial cell interplay in adipose tissue physiology
Published in Biochemical pharmacology (01-04-2024)“…[Display omitted] Adipose tissue (AT) expansion through hyperplasia or hypertrophy requires vascular remodeling that involves angiogenesis. There is quite some…”
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Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD
Published in Journal of hepatology (01-07-2017)“…Graphical abstract…”
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MicroRNA-221-3p Regulates Angiopoietin-Like 8 (ANGPTL8) Expression in Adipocytes
Published in The journal of clinical endocrinology and metabolism (01-11-2017)“…Abstract Context Angiopoietin-like 8 (ANGPTL8) has been identified as a key regulator of lipid metabolism. Design We addressed the correlation between ANGPTL8…”
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Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-07-2017)“…A polymorphism of TM6SF2 associates with hepatic lipid accumulation and reduction of triacylglycerol (TAG) secretion, but the function of the encoded protein…”
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Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition
Published in Chemistry and physics of lipids (01-10-2017)“…•ANGPTL8 regulates adipocyte intracellular lipolysis.•ANGPTL8 is involved in maintaining adipocyte phospholipid composition.•ANGPTL8 regulates the expression…”
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Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease
Published in JCI insight (12-03-2020)“…Carriers of the hydroxysteroid 17-β dehydrogenase 13 (HSD17B13) gene variant (rs72613567:TA) have a reduced risk of NASH and cirrhosis but not steatosis. We…”
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Vismodegib for periocular basal cell carcinoma: an international multicentre case series
Published in Eye (London) (01-11-2020)“…Introduction Vismodegib (Erivedge, Genentech) is a first-in-class inhibitor of the hedgehog (Hh) pathway, which is licensed for use in locally advanced basal…”
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Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes
Published in Molecular medicine (Cambridge, Mass.) (17-06-2022)“…BackgroundThyroid hormone responsive protein (THRSP) is a lipogenic nuclear protein that is highly expressed in murine adipose tissue, but its role in humans…”
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Nondestructive characterization of thermal damages and its interactions in carbon fibre composite panels
Published in Fatigue & fracture of engineering materials & structures (01-10-2017)“…Driven by high strength‐to‐weight ratios and advanced design flexibility, the application of composite structures in the aerospace industry is growing…”
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Elucidation of the glucose transport pathway in glucose transporter 4 via steered molecular dynamics simulations
Published in PloS one (12-10-2011)“…GLUT4 is a predominant insulin regulated glucose transporter expressed in major glucose disposal tissues such as adipocytes and muscles. Under the unstimulated…”
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Upper lid ptosis surgery: what is the optimal interval for the postoperative review? A retrospective review of 300 cases
Published in Eye (London) (01-04-2018)“…Purpose Correction of upper eyelid ptosis is one of the most commonly performed oculoplastic procedures on the NHS but there is currently no data in the…”
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Vanillin induces adipocyte differentiation in 3T3-L1 cells by activating extracellular signal regulated kinase 42/44
Published in Life sciences (1973) (11-04-2011)“…To investigate the effect of vanillin, a dietary component, on adipocyte differentiation and the mechanism involved in the process using 3T3-L1 murine…”
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Short-Term Cooling Increases Plasma ANGPTL3 and ANGPTL8 in Young Healthy Lean Men but Not in Middle-Aged Men with Overweight and Prediabetes
Published in Journal of clinical medicine (14-08-2019)“…Angiopoietin-like proteins (ANGPTLs) regulate triglyceride (TG)-rich lipoprotein distribution via inhibiting TG hydrolysis by lipoprotein lipase in metabolic…”
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Quantification of Subcutaneous and Visceral Fat in Abdominal CT and the Correlation with Metabolic Parameters
Published in Journal of the Association of Physicians of India (01-12-2019)“…The objective of this study was to determine the association of Computed tomography quantified visceral (VAT) and subcutaneous adipose tissue (SAT) with…”
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Adjustable versus non-adjustable sutures for strabismus
Published in Cochrane database of systematic reviews (01-01-2005)“…Strabismus, or squint, can be defined as a deviation from perfect ocular alignment and can be classified in many ways according to its aetiology and…”
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Polyurethanes as potential substrates for sub-retinal retinal pigment epithelial cell transplantation
Published in Journal of materials science. Materials in medicine (01-12-2005)“…Transplantation of cultured retinal pigment epithelial (RPE) cells under the failing macular is a potential treatment for age related macular degeneration. An…”
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Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-12-2020)“…Angiopoietin like protein 3 (ANGPTL3) is best known for its function as an inhibitor of lipoprotein and endothelial lipases. Due to the capacity of genetic or…”
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miR-107 inhibits CDK6 expression, differentiation, and lipid storage in human adipocytes
Published in Molecular and cellular endocrinology (05-01-2019)“…MicroRNA-107 (miR-107) plays a regulatory role in obesity and insulin resistance, but the mechanisms of its function in adipocytes have not been elucidated in…”
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Human visceral adipose tissue microvascular endothelial cell isolation and establishment of co-culture with white adipocytes to analyze cell-cell communication
Published in Experimental cell research (15-12-2023)“…Communication between adipocytes and endothelial cells (EC) is suggested to play an important role in the metabolic function of white adipose tissue. In order…”
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