Search Results - "Haribabu, Bodduluri"
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Back to the future of targeting leukotriene B 4 mediated inflammation
Published in Seminars in immunology (01-10-2017)Get full text
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Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
Published in Nature communications (09-01-2019)“…The importance of gut microbiota in human health and pathophysiology is undisputable. Despite the abundance of metagenomics data, the functional dynamics of…”
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Evidence for a link between gut microbiota and hypertension in the Dahl rat
Published in Physiological genomics (01-06-2015)“…The gut microbiota plays a critical role in maintaining physiological homeostasis. This study was designed to evaluate whether gut microbial composition…”
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Urolithin A attenuates arsenic-induced gut barrier dysfunction
Published in Archives of toxicology (01-04-2022)“…Environmental chemicals such as inorganic arsenic (iAs) significantly contribute to redox toxicity in the human body by enhancing oxidative stress. Imbalanced…”
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Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis
Published in Frontiers in immunology (08-09-2022)“…Cytochrome P450 Family 1 Subfamily A Member 1 (CYP1A1) pathway, which is regulated by aryl hydrocarbon receptor (AhR) plays an important role in chemical…”
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Polystyrene bead ingestion promotes adiposity and cardiometabolic disease in mice
Published in Ecotoxicology and environmental safety (01-03-2022)“…Vast amounts of plastic materials are produced in the modern world and despite recycling efforts, large amounts are disposed in water systems and landfills…”
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Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme Peroxidases
Published in PloS one (02-06-2016)“…Numerous studies signify that diets rich in phytochemicals offer many beneficial functions specifically during pathologic conditions, yet their effects are…”
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Neurodegenerative diseases: from gut-brain axis to brain microbiome
Published in Frontiers in aging neuroscience (19-05-2023)Get full text
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The role for the metagenome in the pathogenesis of COVID-19
Published in EBioMedicine (01-11-2020)Get full text
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Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity
Published in The Journal of immunology (1950) (15-08-2011)“…Chronic inflammation is an underlying factor linking obesity with insulin resistance. Diet-induced obesity promotes an increase in circulating levels of…”
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The yin and yang of leukotriene B 4 mediated inflammation in cancer
Published in Seminars in immunology (01-10-2017)“…The high affinity leukotriene B receptor, BLT1 mediates chemotaxis of diverse leukocyte subsets to the sites of infection or inflammation. Whereas the…”
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Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognition
Published in PLoS pathogens (01-01-2024)“…Subverting the host immune response to inhibit inflammation is a key virulence strategy of Yersinia pestis. The inflammatory cascade is tightly controlled via…”
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Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups
Published in World journal of gastroenterology : WJG (07-03-2015)“…AIM:To investigate differences in microbes and short chain fatty acid(SCFA) levels in stool samples from Hispanic and non-Hispanic African American,American…”
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Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer
Published in BMC cancer (28-12-2012)“…G-protein-coupled estrogen receptor (GPER/GPR30) was reported to bind 17β-estradiol (E2), tamoxifen, and ICI 182,780 (fulvestrant) and promotes activation of…”
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Absence of CCR2 reduces spontaneous intestinal tumorigenesis in the ApcMin/+ mouse model
Published in International journal of cancer (15-05-2021)“…The biological activities of chemokine (C‐C motif) ligand 2 (CCL2) are mediated via C‐C chemokine receptor‐2 (CCR2). Increased CCL2 level is associated with…”
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Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis
Published in Antimicrobial Agents and Chemotherapy (01-03-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica–Induced Sterile Inflammation
Published in The Journal of immunology (1950) (15-05-2018)“…Abstract Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica (CS). Leukotriene B4 (LTB4) plays an important role in…”
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Nonredundant roles for leukotriene B4 receptors BLT1 and BLT2 in inflammatory arthritis
Published in The Journal of immunology (1950) (01-09-2010)“…Lipid mediators derived from arachidonic acid through the cyclooxygenase and lipoxygenase pathways are known to be important mediators of inflammation. Studies…”
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Microbial Metabolite Urolithin B Inhibits Recombinant Human Monoamine Oxidase A Enzyme
Published in Metabolites (19-06-2020)“…Urolithins are gut microbial metabolites derived from ellagitannins (ET) and ellagic acid (EA), and shown to exhibit anticancer, anti-inflammatory,…”
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Zinc Oxide Nanowires Exposure Induces a Distinct Inflammatory Response via CCL11-Mediated Eosinophil Recruitment
Published in Frontiers in immunology (08-11-2019)“…High aspect ratio zinc oxide nanowires (ZnONWs) have become one of the most important products in nanotechnology. The wide range applications of ZnONWs have…”
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