Search Results - "Harhun, Maksym I."
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Expression and function of the K+ channel KCNQ genes in human arteries
Published in British journal of pharmacology (01-01-2011)“…BACKGROUND AND PURPOSE KCNQ‐encoded voltage‐gated potassium channels (Kv7) have recently been identified as important anti‐constrictor elements in rodent blood…”
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Vascular smooth muscle cells from small human omental arteries express P2X1 and P2X4 receptor subunits
Published in Purinergic signalling (01-12-2014)“…Stimulation of P2X receptors by ATP in vascular smooth muscle cells (VSMCs) is proposed to mediate vascular tone. However, understanding of P2X…”
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Mitochondrial Ca2+ handling is crucial for generation of rhythmical Ca2+ waves in vascular interstitial cells from rabbit portal vein
Published in Cell calcium (Edinburgh) (01-09-2015)“…Graphical abstract…”
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Function of Interstitial Cells of Cajal in the Rabbit Portal Vein
Published in Circulation Research (17-09-2004)“…Interstitial cells of Cajal (ICCs) were identified in the intact fixed media of the rabbit portal vein (RPV) using c-kit staining. The following experiments…”
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Downregulation of Kv7.4 Channel Activity in Primary and Secondary Hypertension
Published in Circulation (New York, N.Y.) (02-08-2011)“…Voltage-gated potassium (K(+)) channels encoded by KCNQ genes (Kv7 channels) have been identified in various rodent and human blood vessels as key regulators…”
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Close relation of arterial ICC‐like cells to the contractile phenotype of vascular smooth muscle cell
Published in Journal of cellular and molecular medicine (01-07-2007)“…This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC‐like (AIL) cells, which have recently been…”
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Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter
Published in The Journal of physiology (01-09-2010)“…KCNQ gene expression was previously shown in various rodent blood vessels, where the products of KCNQ4 and KCNQ5, Kv7.4 and Kv7.5 potassium channel subunits,…”
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ATP-Evoked Sustained Vasoconstrictions Mediated by Heteromeric P2X1/4 Receptors in Cerebral Arteries
Published in Stroke (1970) (01-08-2014)“…BACKGROUND AND PURPOSE—Current knowledge states that vasoconstrictor responses to ATP are mediated by rapidly desensitizing ligand-gated P2X1 receptors in…”
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Molecular identification of P2X receptors in vascular smooth muscle cells from rat anterior, posterior, and basilar arteries
Published in Pharmacological reports (01-12-2015)“…Purinergic P2X receptors in vascular smooth muscle cells (VSMCs) play an important role in physiological stimulatory responses to the extracellularly released…”
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Ca2+ entry following P2X receptor activation induces IP3 receptor‐mediated Ca2+ release in myocytes from small renal arteries
Published in British journal of pharmacology (01-04-2011)“…BACKGROUND AND PURPOSE P2X receptors mediate sympathetic control and autoregulation of the renal circulation triggering contraction of renal vascular smooth…”
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Purinoreceptor‐mediated current in myocytes from renal resistance arteries
Published in British journal of pharmacology (01-06-2010)“…Background and purpose: Ionotropic purinoreceptors (P2X) in renal vascular smooth muscle cells (RVSMCs) are involved in mediating the sympathetic control and…”
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Characterization of transcriptional and posttranscriptional properties of native and cultured phenotypically modulated vascular smooth muscle cells
Published in Cell and tissue research (01-05-2013)“…Various in vitro models are used for studying phenotypic modulation of vascular smooth muscle cells (VSMCs) and the established culture of vascular smooth…”
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Mechanisms of the sarcoplasmic reticulum Ca2+ release induced by P2X receptor activation in mesenteric artery myocytes
Published in Pharmacological reports (01-06-2014)“…ATP is one of the principal sympathetic neurotransmitters which contracts vascular smooth muscle cells (SMCs) via activation of ionotropic P2X receptors…”
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Theory and applications of geometric scaling of localized calcium release events
Published in American Journal of Physiology: Cell Physiology (01-11-2010)“…Geometric measures of localized calcium release (LCR) events have been used to understand their biophysical basis. We found power law scaling between three…”
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Mechanisms of [Ca2+]i elevation following P2X receptor activation in the guinea-pig small mesenteric artery myocytes
Published in Pharmacological reports (01-01-2013)“…There is growing evidence suggesting involvement of L-type voltage-gated Ca2+ channels (VGCCs) in purinergic signaling mechanisms. However, detailed interplay…”
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Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries
Published in Journal of cellular and molecular medicine (01-11-2012)“…Vascular interstitial cells (VICs) are non‐contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains…”
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Interstitial cells from rat middle cerebral artery belong to smooth muscle cell type
Published in Journal of cellular and molecular medicine (01-11-2009)“…It is now established that non‐contractile cells with thin filopodia, also called vascular interstitial cells (VICs), are constitutively present in the media…”
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Voltage-gated potassium currents in rat vas deferens smooth muscle cells
Published in Pflügers Archiv (01-06-2003)“…Voltage-gated components of the outward current in single smooth muscle cells isolated from the epididymal part of the rat vas deferens were studied using…”
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Ca 2+ entry following P2X receptor activation induces IP 3 receptor‐mediated Ca 2+ release in myocytes from small renal arteries
Published in British journal of pharmacology (01-04-2011)“…BACKGROUND AND PURPOSE P2X receptors mediate sympathetic control and autoregulation of the renal circulation triggering contraction of renal vascular smooth…”
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