Search Results - "Hargis, Geneva"
-
1
Role of Senescent Cells in Cutaneous Wound Healing
Published in Biology (Basel, Switzerland) (29-11-2022)“…Cellular senescence has gained increasing attention in the field of aging research. Senescent cells have been implicated in biological aging processes,…”
Get full text
Journal Article -
2
Serum integrative omics reveals the landscape of human diabetic kidney disease
Published in Molecular metabolism (Germany) (01-12-2021)“…Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens…”
Get full text
Journal Article -
3
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis
Published in Molecular metabolism (Germany) (01-05-2023)“…In the fibrotic kidneys, the extent of a formed deleterious microenvironment is determined by cellular mechanical forces. This process requires metabolism for…”
Get full text
Journal Article -
4
Calponin 2 regulates ketogenesis to mitigate acute kidney injury
Published in JCI insight (08-11-2023)“…Calponin 2 (CNN2) is a prominent actin stabilizer. It regulates fatty acid oxidation (FAO) by interacting with estrogen receptor 2 (ESR2) to determine kidney…”
Get full text
Journal Article -
5
The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
Published in iScience (22-10-2021)“…The kidney local microenvironment (KLM) plays a critical role in the pathogenesis of kidney fibrosis. However, the composition and regulation of a fibrotic KLM…”
Get full text
Journal Article -
6
Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19
Published in Frontiers in aging (23-07-2021)“…Aging has emerged as the greatest and most prevalent risk factor for the development of severe COVID-19 infection and death following exposure to the…”
Get full text
Journal Article -
7
Impact of bindarit, a CCL2 chemokine synthesis inhibitor, on macrophage-based biofouling and continuous glucose monitoring in vivo
Published in Biosensors and bioelectronics. X (01-08-2024)“…Continuous glucose monitoring (CGM) using implantable glucose sensors is a critical tool in the management of diabetes. Unfortunately, current commercial…”
Get full text
Journal Article -
8
Surface anatomy in dermatology: Part I—Clinical importance, diagnostic utility, and impact on medical management
Published in Journal of the American Academy of Dermatology (01-08-2024)“…This continuing medical education series reviews updated Delphi consensus surface anatomy terminology through the lens of common medical and procedural…”
Get full text
Journal Article -
9
JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte–endothelial proadhesive interactions
Published in Journal of thrombosis and haemostasis (01-05-2023)“…Vascular activation is characterized by increased proinflammatory, pro thrombotic, and proadhesive signaling. Several chronic and acute conditions, including…”
Get full text
Journal Article -
10
Fibroblast expression of transmembrane protein smoothened governs microenvironment characteristics after acute kidney injury
Published in The Journal of clinical investigation (01-07-2024)“…The smoothened (Smo) receptor facilitates hedgehog signaling between kidney fibroblasts and tubules during acute kidney injury (AKI). Tubule-derived hedgehog…”
Get full text
Journal Article -
11
Fibroblast expression of transmembrane protein smoothened governs microenvironment characteristics after acute kidney injury
Published in The Journal of clinical investigation (01-07-2024)“…The smoothened (Smo) receptor facilitates hedgehog signaling between kidney fibroblasts and tubules during acute kidney injury (AKI). Tubule-derived hedgehog…”
Get full text
Journal Article -
12
Surface anatomy in dermatology: Part II—Impact on perioperative management, procedural technique, and cosmesis
Published in Journal of the American Academy of Dermatology (01-08-2024)“…This CME series reviews updated Delphi consensus surface anatomy terminology through the lens of common medical and procedural dermatology scenarios, helping…”
Get full text
Journal Article -
13
Impact of bindarit, a CCL2 chemokine synthesis inhibitor, on macrophage-based biofouling and continuous glucose monitoring invivo
Published in Biosensors and bioelectronics. X (01-08-2024)“…Continuous glucose monitoring (CGM) using implantable glucose sensors is a critical tool in the management of diabetes. Unfortunately, current commercial…”
Get full text
Journal Article -
14
Microfluidic Model Systems to Evaluate Endothelial Cell Phenotype in Disease
Published 01-01-2020“…Macrophages are known contributors to cancer progression in the primary site, but significantly less is known about their roles in secondary tumor formation…”
Get full text
Dissertation -
15