Search Results - "Hargett, Audra A."

Glycosylation of viral surface proteins probed by mass spectrometry by Hargett, Audra A, Renfrow, Matthew B

“…Glycosylation is a common and biologically significant post-translational modification that is found on numerous virus surface proteins (VSPs). Many of these…”
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Defining HIV-1 Envelope N-Glycan Microdomains through Site-Specific Heterogeneity Profiles by Hargett, Audra A, Wei, Qing, Knoppova, Barbora, Hall, Stacy, Huang, Zhi-Qiang, Prakash, Amol, Green, Todd J, Moldoveanu, Zina, Raska, Milan, Novak, Jan, Renfrow, Matthew B

“…The HIV-1 envelope (Env) glycans shield the surface of Env from the immune system and form integral interactions important for a functional Env. To understand…”
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Glycosylation States on Intact Proteins Determined by NMR Spectroscopy by Hargett, Audra A., Marcella, Aaron M., Yu, Huifeng, Li, Chao, Orwenyo, Jared, Battistel, Marcos D., Wang, Lai-Xi, Freedberg, Darón I.

“…Protein glycosylation is important in many organisms for proper protein folding, signaling, cell adhesion, protein-protein interactions, and immune responses…”
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Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies by Wei, Qing, Hargett, Audra A., Knoppova, Barbora, Duverger, Alexandra, Rawi, Reda, Shen, Chen-Hsiang, Farney, S. Katie, Hall, Stacy, Brown, Rhubell, Keele, Brandon F., Heath, Sonya L., Saag, Michael S., Kutsch, Olaf, Chuang, Gwo-Yu, Kwong, Peter D., Moldoveanu, Zina, Raska, Milan, Renfrow, Matthew B., Novak, Jan

“…HIV-1 envelope (Env) N-glycosylation impact virus-cell entry and immune evasion. How each glycan interacts to shape the Env-protein-sugar complex and affects…”
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The structure of a Cryptococcus neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study by Hargett, Audra A., Azurmendi, Hugo F., Crawford, Conor J., Wear, Maggie P., Oscarson, Stefan, Casadevall, Arturo, Freedberg, Darón I.

“…Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and cryptococcal meningitis. The C. neoformans ’ capsular polysaccharide and its…”
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Reversible O‑Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition by Ji, Yang, Sasmal, Aniruddha, Li, Wanqing, Oh, Lisa, Srivastava, Saurabh, Hargett, Audra A, Wasik, Brian R, Yu, Hai, Diaz, Sandra, Choudhury, Biswa, Parrish, Colin R, Freedberg, Darón I, Wang, Lee-Ping, Varki, Ajit, Chen, Xi

“…O-Acetylation is a common naturally occurring modification of carbohydrates and is especially widespread in sialic acids, a family of nine-carbon acidic…”
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Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide by Wear, Maggie P., Hargett, Audra A., Kelly, John E., McConnell, Scott A., Crawford, Conor J., Freedberg, Darón I., Stark, Ruth E., Casadevall, Arturo

“…Microbial polysaccharide characterization requires purification that often involves detergent precipitation and lyophilization. Here we examined…”
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Fungal polysaccharides are altered by lyophilization resulting in decreased antibody binding by Wear, Maggie P., Hargett, Audra A., Kelly, John E., McConnell, Scott A., Freedberg, Darón I., Casadevall, Arturo, Crawford, Conor J., Stark, Ruth E.

“…The capsule of Cryptococcus neoformans is unique in the fungal kingdom. Its hydrophilic nature and relative neutrality have complicated characterization (1)…”
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Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant S. aureus by Crawford, Cameron L, Dalecki, Alex G, Narmore, Whitney T, Hoff, Jessica, Hargett, Audra A, Renfrow, Matthew B, Zhang, Man, Kalubowilage, Madumali, Bossmann, Stefan H, Queern, Stacy L, Lapi, Suzanne E, Hunter, Robert N, Bao, Donghui, Augelli-Szafran, Corinne E, Kutsch, Olaf, Wolschendorf, Frank

“…The treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections poses a therapeutic challenge as even last resort drugs become increasingly…”
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The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study by Hargett, Audra A, Azurmendi, Hugo F, Crawford, Conor J, Wear, Maggie P, Oscarson, Stefan, Casadevall, Arturo, Freedberg, Darón I

“…is a fungal pathogen responsible for cryptococcosis and cryptococcal meningitis. The ' capsular polysaccharide and its shed exopolysaccharide function both as…”
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Biologically Active Circulatory Immune Complexes in IgA Nephropathy Contain Polymeric IgA1, With Galactose-Deficient and Minimally Sialylated O-Glycans, IgG, and Complement C3b and iC3b: SA-PO641 by Hall, Stacy D., Coffee, Sarah, Huang, Zhi qiang, Maillard, Nicolas, Moldoveanu, Zina, Hargett, Audra A., Rizk, Dana, Julian, Bruce A., Renfrow, Matthew B., Novak, Jan

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Immune Complexes in the Peripheral Blood of Patients with IgA Nephropathy Contain Polymeric Galactose-Deficient IgA1 Associated with IgG and Complement C3: PO1448 by Hall, Stacy D., Coffee, Sarah, Maillard, Nicolas, Moldoveanu, Zina, Craine, Ellenore P., Hargett, Audra A., Rizk, Dana, Julian, Bruce A., Renfrow, Matthew B., Novak, Jan

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Developing Molecular-Specific Biomarker Assays for IgA Nephropathy and IgA Vasculitis with Nephritis: PO1801 by Hansen, Alyssa L., Craine, Ellenore P., Hargett, Audra A., Hall, Stacy D., Rizk, Dana, Julian, Bruce A., Novak, Jan, Renfrow, Matthew B.

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Identification of Proteins Associated with IgA1-Containing Circulating Immune Complexes in Patients with IgA Nephropathy: PO1798 by Bunten, Mary A., Holloway, Amanda, Hargett, Audra A., Hall, Stacy D., Huang, Zhi qiang, Maillard, Nicolas, Julian, Bruce A., Novak, Jan, Renfrow, Matthew B.

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Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant S. aureusElectronic supplementary information (ESI) available. See DOI: 10.1039/c8mt00316e by Crawford, Cameron L, Dalecki, Alex G, Narmore, Whitney T, Hoff, Jessica, Hargett, Audra A, Renfrow, Matthew B, Zhang, Man, Kalubowilage, Madumali, Bossmann, Stefan H, Queern, Stacy L, Lapi, Suzanne E, Hunter, Robert N, Bao, Donghui, Augelli-Szafran, Corinne E, Kutsch, Olaf, Wolschendorf, Frank

“…The treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections poses a therapeutic challenge as even last resort drugs become increasingly…”
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