Search Results - "Hargens, Alan R"

Long-duration bed rest as an analog to microgravity by Hargens, Alan R, Vico, Laurence

“…Long-duration bed rest is widely employed to simulate the effects of microgravity on various physiological systems, especially for studies of bone, muscle, and…”
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Spaceflight-Induced Intracranial Hypertension and Visual Impairment: Pathophysiology and Countermeasures by Zhang, Li-Fan, Hargens, Alan R

“…Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained major risk for future long-duration spaceflight. NASA recently redefined…”
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Ground-Based Analogs for Human Spaceflight by Pandiarajan, Meenakshi, Hargens, Alan R.

“…This mini-review provides an updated summary of various analogs for adaptations of humans to the microgravity of space. Microgravity analogs discussed in this…”
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The Mobile Lower Body Negative Pressure Gravity Suit for Long-Duration Spaceflight by Ashari, Neeki, Hargens, Alan R.

“…Spaceflight Associated Neuro-ocular Syndrome, bone decalcification, and muscle atrophy are among the most prevalent risks associated with long-duration…”
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From the international space station to the clinic: how prolonged unloading may disrupt lumbar spine stability by Bailey, Jeannie F., Miller, Stephanie L., Khieu, Kristine, O'Neill, Conor W., Healey, Robert M., Coughlin, Dezba G., Sayson, Jojo V., Chang, Douglas G., Hargens, Alan R., Lotz, Jeffrey C.

“…Prolonged microgravity exposure is associated with localized low back pain and an elevated risk of post-flight disc herniation. Although the mechanisms by…”
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Noninvasive diagnostics for extremity compartment syndrome following traumatic injury: A state-of-the-art review by Walters, Thomas J, Kottke, Melissa A, Hargens, Alan R, Ryan, Kathy L

“…Acute compartment syndrome (ACS) is a serious medical condition that can occur following traumatic injury to an extremity. If left undiagnosed, ACS can…”
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Cardiovascular, Lymphatic, and Ocular Health in Space by Ly, Victoria, Velichala, Suhas Rao, Hargens, Alan R

“…Life on Earth has evolved continuously under Earth's 1 G force and the protection of the magnetosphere. Thus, astronauts exhibit maladaptive physiological…”
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Fifteen days of microgravity causes growth in calvaria of mice by Zhang, Bing, Cory, Esther, Bhattacharya, Roshmi, Sah, Robert, Hargens, Alan R

“…Abstract Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone…”
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Spaceflight-Associated Vascular Remodeling and Gene Expression in Mouse Calvaria by Siamwala, Jamila H, Macias, Brandon R, Healey, Robert, Bennett, Brett, Hargens, Alan R

“…Astronauts suffer from a loss of bone mass at a rate of 1.5% per month from lower regions of the body during the course of long-duration (>30 days)…”
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Spaceflight-induced bone loss alters failure mode and reduces bending strength in murine spinal segments by Berg-Johansen, Britta, Liebenberg, Ellen C., Li, Alfred, Macias, Brandon R., Hargens, Alan R., Lotz, Jeffrey C.

“…ABSTRACT Intervertebral disc herniation rates are quadrupled in astronauts following spaceflight. While bending motions are main contributors to herniation,…”
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Self-Generated Lower Body Negative Pressure Exercise: A Low Power Countermeasure for Acute Space Missions by Velichala, Suhas Rao, Kassel, Ryan D, Ly, Victoria, Watenpaugh, Donald E, Lee, Stuart M C, Macias, Brandon R, Hargens, Alan R

“…Microgravity in spaceflight produces headward fluid shifts which probably contribute to Spaceflight-Associated Neuro-Ocular Syndrome (SANS). Developing new…”
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Cardiac atrophy in women following bed rest by Dorfman, Todd A, Levine, Benjamin D, Tillery, Tommy, Peshock, Ronald M, Hastings, Jeff L, Schneider, Suzanne M, Macias, Brandon R, Biolo, Gianni, Hargens, Alan R

“…1 Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and 2 Division of Cardiology, Department of Internal Medicine, University…”
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Body posture and backpack loading: an upright magnetic resonance imaging study of the adult lumbar spine by Shymon, Stephen, Hargens, Alan R., Minkoff, Lawrence A., Chang, Douglas G.

“…Purpose Axial loading of the spine while supine, simulating upright posture, decreases intervertebral disc (IVD) height and lumbar length and increases lumbar…”
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Maximizing information from space data resources: a case for expanding integration across research disciplines by Goswami, Nandu, Batzel, Jerry J., Clément, Gilles, Stein, T. Peter, Hargens, Alan R., Sharp, M. Keith, Blaber, Andrew P., Roma, Peter G., Hinghofer-Szalkay, Helmut G.

“…Regulatory systems are affected in space by exposure to weightlessness, high-energy radiation or other spaceflight-induced changes. The impact of spaceflight…”
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Movement-Induced Knot Migration After Anterior Stabilization in the Shoulder by Kim, Sae Hoon, M.D., Ph.D, Crater, Ronald B., M.D., D.P.T, Hargens, Alan R., Ph.D

“…Purpose This study compared the status of suture knots immediately after repair and after shoulder motion to evaluate the possibility of movement-induced knot…”
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The Effect of Backpacks on the Lumbar Spine in Children: A Standing Magnetic Resonance Imaging Study by NEUSCHWANDER, Timothy B, CUTRONE, John, MACIAS, Brandon R, CUTRONE, Samantha, MURTHY, Gita, CHAMBERS, Henry, HARGENS, Alan R

“…This study is a repeated measures design to measure the lumbar spine response to typical school backpack loads in healthy children. The lumbar spine in this…”
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Thirty days of spaceflight does not alter murine calvariae structure despite increased Sost expression by Macaulay, Timothy R, Siamwala, Jamila H, Hargens, Alan R, Macias, Brandon R

“…Previously our laboratory documented increases in calvaria bone volume and thickness in mice exposed to 15 days of spaceflight aboard the NASA Shuttle mission…”
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Comparing two devices of suspended treadmill walking by varying body unloading and Froude number by Ruckstuhl, Heidi, Kho, Jenniefer, Weed, Matthew, Wilkinson, Miles W, Hargens, Alan R

“…Abstract In rehabilitation, treadmill walking with body weight support is commonly used to reduce loads on lower extremities. (1) However, gait pattern…”
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Reply to Bateman and Bateman by Arbeille, Philippe, Hargens, Alan R.

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Aging Decreases Hand Volume Expansion with Water Immersion by Siamwala, Jamila H, Moossazadeh, Davina G, Macaulay, Timothy R, Becker, Rachel L, Hargens, Rekha H, Hargens, Alan R

“…Hands may show early signs of aging with altered skin texture, skin permeability and vascular properties. In clinics, a hand volumeter is used to measure…”
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