Search Results - "Haren, Keith"

Immunotherapy in Autoimmune Encephalitis: So Many Options, So Few Guidelines by Srivastava, Isha N, Van Haren, Keith P

Get full text

Effect of vitamin D supplementation on cerebral blood flow in male patients with adrenoleukodystrophy by Zhao, Moss Y., Dahlen, Alex, Ramirez, Norma Jimenez, Moseley, Michael, Van Haren, Keith, Zaharchuk, Greg

“…One‐third of boys with X‐linked adrenoleukodystrophy (ALD) develop inflammatory demyelinating lesions, typically at the splenium. These lesions share…”
Get full text

Decision Making in Adrenoleukodystrophy: When Is a Good Outcome Really a Good Outcome? by Van Haren, Keith, Engelen, Marc

Get more information

A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012–14): a retrospective cohort study by Greninger, Alexander L, MD, Naccache, Samia N, PhD, Messacar, Kevin, MD, Clayton, Anna, BSc, Yu, Guixia, BSc, Somasekar, Sneha, BSc, Federman, Scot, BA, Stryke, Doug, BSc, Anderson, Christopher, BSc, Yagi, Shigeo, PhD, Messenger, Sharon, PhD, Wadford, Debra, PhD, Xia, Dongxiang, MD, Watt, James P, MD, Van Haren, Keith, MD, Dominguez, Samuel R, MD, Glaser, Carol, MD, Aldrovandi, Grace, Prof, Chiu, Charles Y, Dr

“…Summary Background Enterovirus D68 was implicated in a widespread outbreak of severe respiratory illness across the USA in 2014 and has also been reported…”
Get full text

Longitudinal natural history studies based on real-world data in rare diseases: Opportunity and a novel approach by Adang, Laura Ann, Sevagamoorthy, Anjana, Sherbini, Omar, Fraser, Jamie L., Bonkowsky, Joshua L., Gavazzi, Francesco, D'Aiello, Russel, Modesti, Nicholson B., Yu, Emily, Mutua, Sylvia, Kotes, Emma, Shults, Justine, Vincent, Ariel, Emrick, Lisa T., Keller, Stephanie, Van Haren, Keith P., Woidill, Sarah, Barcelos, Isabella, Pizzino, Amy, Schmidt, Johanna L., Eichler, Florian, Fatemi, Ali, Vanderver, Adeline

“…Growing interest in therapeutic development for rare diseases necessitate a systematic approach to the collection and curation of natural history data that can…”
Get full text

Randomized Clinical Trial of First‐Line Genome Sequencing in Pediatric White Matter Disorders by Vanderver, Adeline, Bernard, Geneviève, Helman, Guy, Sherbini, Omar, Boeck, Ryan, Cohn, Jeffrey, Collins, Abigail, Demarest, Scott, Dobbins, Katherine, Emrick, Lisa, Fraser, Jamie L., Masser‐Frye, Diane, Hayward, Jean, Karmarkar, Swati, Keller, Stephanie, Mirrop, Samuel, Mitchell, Wendy, Pathak, Sheel, Sherr, Elliott, Haren, Keith, Waters, Erica, Wilson, Jenny L., Zhorne, Leah, Schiffmann, Raphael, Knaap, Marjo S., Pizzino, Amy, Dubbs, Holly, Shults, Justine, Simons, Cas, Taft, Ryan J.

“…Objective Genome sequencing (GS) is promising for unsolved leukodystrophies, but its efficacy has not been prospectively studied. Methods A prospective…”
Get full text

Presymptomatic Lesion in Childhood Cerebral Adrenoleukodystrophy: Timing and Treatment by Mallack, Eric James, Van Haren, Keith P., Torrey, Anna, van de Stadt, Stephanie, Engelen, Marc, Raymond, Gerald V., Fatemi, Ali, Eichler, Florian S.

“…We sought to characterize the natural history and standard-of-care practices between the radiologic appearance of brain lesions, the appearance of lesional…”
Get full text

International Recommendations for the Diagnosis and Management of Patients With Adrenoleukodystrophy: A Consensus-Based Approach by Engelen, Marc, van Ballegoij, Wouter J.C., Mallack, Eric James, Van Haren, Keith P., Köhler, Wolfgang, Salsano, Ettore, van Trotsenburg, A.S.P., Mochel, Fanny, Sevin, Caroline, Regelmann, Molly O., Tritos, Nicholas A., Halper, Alyssa, Lachmann, Robin H., Davison, James, Raymond, Gerald V., Lund, Troy C., Orchard, Paul J., Kuehl, Joern-Sven, Lindemans, Caroline A., Caruso, Paul, Turk, Bela Rui, Moser, Ann B., Vaz, Frédéric M., Ferdinandusse, Sacha, Kemp, Stephan, Fatemi, Ali, Eichler, Florian S., Huffnagel, Irene C.

“…Pathogenic variants in the ABCD1 gene cause adrenoleukodystrophy (ALD), a progressive metabolic disorder characterized by 3 core clinical syndromesa slowly…”
Get full text

Pediatric Bickerstaff brainstem encephalitis: a systematic review of literature and case series by Santoro, Jonathan Douglas, Lazzareschi, Daniel V., Campen, Cynthia Jane, Van Haren, Keith P.

“…Objective To characterize the phenotype of pediatric Bickerstaff’s brainstem encephalitis (BBE) and evaluate prognostic features in the clinical course,…”
Get full text

A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets by Hashemi, Ezzat, Srivastava, Isha N, Aguirre, Alejandro, Yoseph, Ezra T, Kaushal, Esha, Awani, Avni, Ryu, Jae K, Akassoglou, Katerina, Talebian, Shahrzad, Chu, Pauline, Pisani, Laura, Musolino, Patricia, Steinman, Lawrence, Doyle, Kristian, Robinson, William H, Sharpe, Orr, Cayrol, Romain, Orchard, Paul J, Lund, Troy, Vogel, Hannes, Lenail, Max, Han, May H, Bonkowsky, Joshua L, Van Haren, Keith P

“…X-linked adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a peroxisomal gene. More than half of males with an ABCD1 mutation develop inflammatory…”
Get full text

Five men with arresting and relapsing cerebral adrenoleukodystrophy by Carlson, Aaron M., Huffnagel, Irene C., Verrips, Aad, van der Knaap, Marjo S., Engelen, Marc, Van Haren, Keith

“…Background X-linked adrenoleukodystrophy (ALD) is the most common genetic peroxisomal disorder with an estimated prevalence of 1:15,000. Approximately…”
Get full text

Pneumonia Prevention Strategies for Children With Neurologic Impairment by Lin, Jody L, Van Haren, Keith, Rigdon, Joseph, Saynina, Olga, Song, Hannah, Buu, MyMy C, Thakur, Yogita, Srinivas, Nivedita, Asch, Steven M, Sanders, Lee M

“…Children with neurologic impairment (NI) face high risk of recurrent severe pneumonia, with prevention strategies of unknown effectiveness. We evaluated the…”
Get full text

Vitamin D status and latitude predict brain lesions in adrenoleukodystrophy by van Haren, Keith P., Wilkes, Jacob, Moser, Ann B., Raymond, Gerald V., Richardson, Troy, Aubourg, Patrick, Collins, Timothy W., Mowry, Ellen M., Bonkowsky, Joshua L.

“…Abstract Objectives Approximately 40% of boys with X‐linked adrenoleukodystrophy (ALD) develop inflammatory demyelinating brain lesions (cerebral ALD, cALD)…”
Get full text

Magnetic resonance imaging spectrum of succinate dehydrogenase-related infantile leukoencephalopathy by Helman, Guy, Caldovic, Ljubica, Whitehead, Matthew T., Simons, Cas, Brockmann, Knut, Edvardson, Simon, Bai, Renkui, Moroni, Isabella, Taylor, J. Michael, Van Haren, Keith, Taft, Ryan J., Vanderver, Adeline, van der Knaap, Marjo S.

“…Objective Succinate dehydrogenase–deficient leukoencephalopathy is a complex II–related mitochondrial disorder for which the clinical phenotype, neuroimaging…”
Get full text

Acute flaccid myelitis: A clinical review of US cases 2012-2015 by Messacar, Kevin, Schreiner, Teri L., Van Haren, Keith, Yang, Michele, Glaser, Carol A., Tyler, Kenneth L., Dominguez, Samuel R.

“…This review highlights clinical features of the increasing cases of acute flaccid paralysis associated with anterior myelitis noted in the United States from…”
Get full text

Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient by Cellucci, Tania, Van Mater, Heather, Graus, Francesc, Muscal, Eyal, Gallentine, William, Klein-Gitelman, Marisa S., Benseler, Susanne M., Frankovich, Jennifer, Gorman, Mark P., Van Haren, Keith, Dalmau, Josep, Dale, Russell C.

“…Autoimmune encephalitis (AE) is an important and treatable cause of acute encephalitis. Diagnosis of AE in a developing child is challenging because of overlap…”
Get full text

Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis by Sotirchos, Elias S, Bhargava, Pavan, Eckstein, Christopher, Van Haren, Keith, Baynes, Moira, Ntranos, Achilles, Gocke, Anne, Steinman, Lawrence, Mowry, Ellen M, Calabresi, Peter A

“…OBJECTIVE:To study the safety profile and characterize the immunologic effects of high- vs low-dose cholecalciferol supplementation in patients with multiple…”
Get full text

MRI surveillance of boys with X‐linked adrenoleukodystrophy identified by newborn screening: Meta‐analysis and consensus guidelines by Mallack, Eric J., Turk, Bela R., Yan, Helena, Price, Carrie, Demetres, Michelle, Moser, Ann B., Becker, Catherine, Hollandsworth, Kim, Adang, Laura, Vanderver, Adeline, Van Haren, Keith, Ruzhnikov, Maura, Kurtzberg, Joanne, Maegawa, Gustavo, Orchard, Paul J., Lund, Troy C., Raymond, Gerald V., Regelmann, Molly, Orsini, Joseph J., Seeger, Elisa, Kemp, Stephan, Eichler, Florian, Fatemi, Ali

“…Background Among boys with X‐Linked adrenoleukodystrophy, a subset will develop childhood cerebral adrenoleukodystrophy (CCALD). CCALD is typically lethal…”
Get full text

Acute Flaccid Myelitis of Unknown Etiology in California, 2012-2015 by Van Haren, Keith, Ayscue, Patrick, Waubant, Emmanuelle, Clayton, Anna, Sheriff, Heather, Yagi, Shigeo, Glenn-Finer, Rose, Padilla, Tasha, Strober, Jonathan B, Aldrovandi, Grace, Wadford, Debra A, Chiu, Charles Y, Xia, Dongxiang, Harriman, Kathleen, Watt, James P, Glaser, Carol A

“…IMPORTANCE: There has been limited surveillance for acute flaccid paralysis in North America since the regional eradication of poliovirus. In 2012, the…”
Get full text

Therapeutic Advances in Pediatric Multiple Sclerosis by Van Haren, Keith, MD, Waubant, Emmanuelle, MD, PhD

Get full text