Search Results - "Harej, Anja"

Data-Driven Modelling of Substituted Pyrimidine and Uracil-Based Derivatives Validated with Newly Synthesized and Antiproliferative Evaluated Compounds by Zukić, Selma, Osmanović, Amar, Harej Hrkać, Anja, Kraljević Pavelić, Sandra, Špirtović-Halilović, Selma, Veljović, Elma, Roca, Sunčica, Trifunović, Snežana, Završnik, Davorka, Maran, Uko

“…The pyrimidine heterocycle plays an important role in anticancer research. In particular, the pyrimidine derivative families of uracil show promise as…”
Get full text

The Therapeutic Potential of Glucagon-like Peptide 1 Receptor Agonists in Traumatic Brain Injury by Harej Hrkać, Anja, Pilipović, Kristina, Belančić, Andrej, Juretić, Lea, Vitezić, Dinko, Mršić-Pelčić, Jasenka

“…Traumatic brain injury (TBI), which is a global public health concern, can take various forms, from mild concussions to blast injuries, and each damage type…”
Get full text

Chemically Functionalized Single-Walled Carbon Nanotubes Prevent the Reduction in Plasmalemmal Glutamate Transporter EAAT1 Expression in, and Increase the Release of Selected Cytokines from, Stretch-Injured Astrocytes in Vitro by Gržeta Krpan, Nika, Harej Hrkać, Anja, Janković, Tamara, Dolenec, Petra, Bekyarova, Elena, Parpura, Vladimir, Pilipović, Kristina

“…We tested the effects of water-soluble single-walled carbon nanotubes, chemically functionalized with polyethylene glycol (SWCNT-PEG), on primary mouse…”
Get full text

Modeling Central Nervous System Injury In Vitro: Current Status and Promising Future Strategies by Pilipović, Kristina, Harej Hrkać, Anja, Kučić, Natalia, Mršić-Pelčić, Jasenka

“…The central nervous system (CNS) injury, which occurs because of mechanical trauma or ischemia/hypoxia, is one of the main causes of mortality and morbidity in…”
Get full text

EXPLORING THE EFFECTS OF CHEMICALLY FUNCTIONALIZED SINGLE-WALLED CARBON NANOTUBES ON SOD1, GPX1, AND NRF2 REGULATION IN PRIMARY MOUSE ASTROCYTES EXPOSED TO IN VITRO STRETCH INJURY by Hrkać, Anja Harej, Gržeta, Nika, Parpura, Vladimir, Pilipović, Kristina

Get full text

Green Solvent-Free Synthesis of New N -Heterocycle-L-Ascorbic Acid Hybrids and Their Antiproliferative Evaluation by Popov, Andrea Bistrović, Macan, Andrijana Meščić, Jakopec, Silvio, Prpić, Helena, Hrkać, Anja Harej, Pavelić, Sandra Kraljević, Raić-Malić, Silvana

Get full text

The Antioxidant and Antiproliferative Activities of 1,2,3-Triazolyl-L-Ascorbic Acid Derivatives by Harej, Anja, Macan, Andrijana Meščić, Stepanić, Višnja, Klobučar, Marko, Pavelić, Krešimir, Pavelić, Sandra Kraljević, Raić-Malić, Silvana

“…The novel 4-substituted 1,2,3-triazole L-ascorbic acid (L-ASA) conjugates with hydroxyethylene spacer as well as their conformationally restricted…”
Get full text

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549 by Bistrović, Andrea, Grbčić, Petra, Harej, Anja, Sedić, Mirela, Kraljević-Pavelić, Sandra, Koštrun, Sanja, Plavec, Janez, Makuc, Damjan, Raić-Malić, Silvana

“…Novel halogenated purines and pseudopurines with diverse aryl-substituted 1,2,3-triazoles were prepared. While p-(trifluoromethyl)-substituted 1,2,3-triazole…”
Get full text

Synthesis, Biological Evaluation and Docking Studies of Benzoxazoles Derived from Thymoquinone by Glamočlija, Una, Padhye, Subhash, Špirtović-Halilović, Selma, Osmanović, Amar, Veljović, Elma, Roca, Sunčica, Novaković, Irena, Mandić, Boris, Turel, Iztok, Kljun, Jakob, Trifunović, Snežana, Kahrović, Emira, Kraljević Pavelić, Sandra, Harej, Anja, Klobučar, Marko, Završnik, Davorka

“…Thymoquinone ( ), a natural compound with antimicrobial and antitumor activity, was used as the starting molecule for the preparation of 3-aminothymoquinone (…”
Get full text

Synthesis and Anti-Proliferative Effects of Mono- and Bis-Purinomimetics Targeting Kinases by Bistrović, Andrea, Harej, Anja, Grbčić, Petra, Sedić, Mirela, Kraljević Pavelić, Sandra, Cetina, Mario, Raić-Malić, Silvana

“…A series of mono-pyrrolo[2,3- ]pyrimidines - , unsymmetrical bis-purine isosteres - and symmetrical bis-pyrrolo[2,3- ]pyrimidines and connected via…”
Get full text

Antimicrobial and Antiproliferative Activities and Enzyme Binding Affinity of Xanthen-3-one Derivatives by Elma Veljović, Anja Harej, Marko Klobučar, Sandra Kraljević Pavelić, Selma Špirtović-Halilović, Amar Osmanović, Samija Muratović, Mirsada Salihović, Davorka Završnik

“…Ten biologically active derivatives of 2,6,7-trihydroxyxanthen-3-one, previously synthesized and characterised, were investigated for their in vitro…”
Get full text

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole–coumarin hybrids by Kraljević, Tatjana Gazivoda, Harej, Anja, Sedić, Mirela, Pavelić, Sandra Kraljević, Stepanić, Višnja, Drenjančević, Domagoj, Talapko, Jasminka, Raić-Malić, Silvana

“…The 4-substituted 1,2,3-triazole core in designed coumarin hybrids (4–35) with diverse physicochemical properties was introduced by eco-friendly…”
Get full text

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer by Bistrović, Andrea, Krstulović, Luka, Harej, Anja, Grbčić, Petra, Sedić, Mirela, Koštrun, Sanja, Pavelić, Sandra Kraljević, Bajić, Miroslav, Raić-Malić, Silvana

“…A series of novel amidino 2-substituted benzimidazoles linked to 1,4-disubstituted 1,2,3-triazoles were synthesized by implementation of microwave and…”
Get full text

Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives by Macan, Andrijana Meščić, Harej, Anja, Cazin, Ines, Klobučar, Marko, Stepanić, Višnja, Pavelić, Krešimir, Pavelić, Sandra Kraljević, Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Raić-Malić, Silvana

“…Two series of 6-(1,2,3-triazolyl)-2,3-dibenzyl-l-ascorbic acid derivatives with the hydroxyethylene (8a−8u) and ethylidene linkers (10c−10p) were synthesized…”
Get full text

Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties by Cindrić, Maja, Jambon, Samy, Harej, Anja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Kraljević Pavelić, Sandra, Karminski-Zamola, Grace, Hranjec, Marijana

“…Within this manuscript design, synthesis of novel 2-imidazolinyl substituted benzo[b]thieno-2-carboxamides bearing either benzimidazole or benzothiazole…”
Get full text

In vitro anticancer activity of binuclear Ru(II) complexes with Schiff bases derived from 5-substituted salicylaldehyde and 2-aminopyridine with notably low IC50 values by Kahrović, Emira, Zahirović, Adnan, Kraljević Pavelić, Sandra, Turkušić, Emir, Harej, Anja

“…The binuclear Ru(II) complexes with Schiff bases derived from 5-chlorosalicyladehyde and 2-aminopyridine and its 5-substituted salicylideneimine homologues…”
Get full text

Supramolecular solid-state structure, potential energy surfaces and evaluation of antiproliferative effect of 2-benzothiazolylhydrazone derivatives in vitro by Katava, Robert, Pavelić, Sandra Kraljević, Harej, Anja, Hrenar, Tomica, Pavlović, Gordana

“…The in situ condensation reaction of 2-hydrazinobenzothiazole with salicylaldehyde, 3,4-dihydroxybenzaldehyde, 2,4-dihydroxybenzaldehyde,…”
Get full text

Heteroleptic ruthenium bioflavonoid complexes: from synthesis to in vitro biological activity by Zahirović, Adnan, Kahrović, Emira, Cindrić, Marina, Kraljević Pavelić, Sandra, Hukić, Mirsada, Harej, Anja, Turkušić, Emir

“…Heteroleptic ruthenium(II) bioflavonoid complexes of quercetin, morin, chrysin, and 3-hydroxyflavone were prepared and their interaction with CT DNA and BSA…”
Get full text

In vitro anticancer activity of binuclear Ru(II) complexes with Schiff bases derived from 5-substituted salicylaldehyde and 2-aminopyridine with notably low IC 50 values by Kahrović, Emira, Zahirović, Adnan, Kraljević Pavelić, Sandra, Turkušić, Emir, Harej, Anja

Get full text

Synthesis, characterisation and in vitro investigation of photodynamic activity of 5-(4-octadecanamidophenyl)-10,15,20-tris( N -methylpyridinium-3-yl)porphyrin trichloride on HeLa cells using low light fluence rate by Malatesti, Nela, Harej, Anja, Kraljević Pavelić, Sandra, Lončarić, Martin, Zorc, Hrvoje, Wittine, Karlo, Andjelkovic, Uros, Josic, Djuro

“…Graphical abstract…”
Get full text