Search Results - "Hardy, R.S."

Effects of glucocorticoids on wnt expression in synovial fibroblasts: potential role in inflammatory bone loss by Hardy, R.S, Ahasan, M, Patel, P, Rabbitt, E, Filer, A, Raza, K, Stewart, P, Buckley, C.D, Cooper, M.S

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11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis by Hardy, R.S., Fenton, C., Croft, A.P., Naylor, A.J., Begum, R., Desanti, G., Buckley, C.D., Lavery, G., Cooper, M.S., Raza, K.

“…In rheumatoid arthritis, the enzyme 11 beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is highly expressed at sites of inflammation, where it converts…”
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Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis by Martin, C.S, Crastin, A., Sagmeister, M.S., Kalirai, M.S., Turner, J.D., MacDonald, L., Kurowska-Stolarska, M., Scheel-Toellner, D., Taylor, A.E., Gilligan, L.C., Storbeck, K., Price, M., Gorvin, C.M., A, Filer, Mahida, R., Clark, A.R., Jones, S.W., Raza, K., Hewison, M., Hardy, R.S.

“…In inflammatory diseases such as rheumatoid arthritis (RA), steroid metabolism is a central component mediating the actions of immuno-modulatory…”
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