Search Results - "Hardy, Linda"

The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs by Banik, Jewel, Moreira, Ana Rita Silva, Lim, Juchan, Tomlinson, Sophia, Hardy, Linda L., Lagasse, Alex, Haney, Anessa, Crimmins, Meghan R., Boehm, Ulrich, Odle, Angela K., MacNicol, Melanie C., Childs, Gwen V., MacNicol, Angus M.

“…The pituitary functions as a master endocrine gland that secretes hormones critical for regulation of a wide variety of physiological processes including…”
Get full text

Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation by Cragle, Chad E., MacNicol, Melanie C., Byrum, Stephanie D., Hardy, Linda L., Mackintosh, Samuel G., Richardson, William A., Gray, Nicola K., Childs, Gwen V., Tackett, Alan J., MacNicol, Angus M.

“…The Musashi family of mRNA translational regulators controls both physiological and pathological stem cell self-renewal primarily by repressing target mRNAs…”
Get full text

Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements by Rutledge, Charlotte E, Lau, Ho-Tak, Mangan, Hazel, Hardy, Linda L, Sunnotel, Olaf, Guo, Fan, MacNicol, Angus M, Walsh, Colum P, Lees-Murdock, Diane J

“…Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27…”
Get full text

Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators by Allensworth‐James, Melody L., Odle, Angela K., Lim, Juchan, LaGasse, Alex N., Miles, Tiffany K., Hardy, Linda L., Haney, Anessa C., MacNicol, Melanie C., MacNicol, Angus M., Childs, Gwen V.

“…In normal individuals, pituitary somatotrophs optimise body composition by responding to metabolic signals from leptin. To identify mechanisms behind the…”
Get full text

Enforcing temporal control of maternal mRNA translation during oocyte cell-cycle progression by Arumugam, Karthik, Wang, Yiying, Hardy, Linda L, MacNicol, Melanie C, MacNicol, Angus M

“…Meiotic cell‐cycle progression in progesterone‐stimulated Xenopus oocytes requires that the translation of pre‐existing maternal mRNAs occur in a strict…”
Get full text

Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2 by MacNicol, Melanie C., Cragle, Chad E., McDaniel, F. Kennedy, Hardy, Linda L., Wang, Yan, Arumugam, Karthik, Rahmatallah, Yasir, Glazko, Galina V., Wilczynska, Ania, Childs, Gwen V., Zhou, Daohong, MacNicol, Angus M.

“…The Musashi family of RNA binding proteins act to promote stem cell self-renewal and oppose cell differentiation predominantly through translational repression…”
Get full text

Neural stem and progenitor cell fate transition requires regulation of Musashi1 function by MacNicol, Angus M, Hardy, Linda L, Spencer, Horace J, MacNicol, Melanie C

“…There is increasing evidence of a pivotal role for regulated mRNA translation in control of developmental cell fate transitions. Physiological and pathological…”
Get full text

Ringo/Cyclin-dependent Kinase and Mitogen-activated Protein Kinase Signaling Pathways Regulate the Activity of the Cell Fate Determinant Musashi to Promote Cell Cycle Re-entry in Xenopus Oocytes by Arumugam, Karthik, MacNicol, Melanie C., Wang, Yiying, Cragle, Chad E., Tackett, Alan J., Hardy, Linda L., MacNicol, Angus M.

“…Cell cycle re-entry during vertebrate oocyte maturation is mediated through translational activation of select target mRNAs, culminating in the activation of…”
Get full text

Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression by Penthala, Narsimha R., Bommagani, Shobanbabu, Janganati, Venumadhav, MacNicol, Kenzie B., Cragle, Chad E., Madadi, Nikhil R., Hardy, Linda L., MacNicol, Angus M., Crooks, Peter A.

“…(E)-13-(Aryl/heteroaryl)parthenolides (5a–i and 6a–i) were synthesized and evaluated for their ability to modify cell cycle progression during…”
Get full text

FRI289 It Takes A Village: Musashi And Its Associated Proteins In The Adenohypophysis by Bronson, Katherine L, Hardy, Linda, Lagasse, Alexandra, MacNicol, Angus M

“…Abstract Disclosure: K.L. Bronson: None. L. Hardy: None. A. Lagasse: None. A.M. MacNicol: None. Musashi is an RNA-binding protein that regulates stem and…”
Get full text

Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle by Moreira, Ana Rita Silva, Lim, Juchan, Urbaniak, Alicja, Banik, Jewel, Bronson, Katherine, Lagasse, Alex, Hardy, Linda, Haney, Anessa, Allensworth, Melody, Miles, Tiffany K, Gies, Allen, Byrum, Stephanie D, Wilczynska, Ania, Boehm, Ulrich, Kharas, Michael, Lengner, Christopher, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M, Odle, Angela K

“…Abstract The anterior pituitary controls key biological processes, including growth, metabolism, reproduction, and stress responses through distinct cell types…”
Get full text

Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi by Allensworth-James, Melody, Banik, Jewel, Odle, Angela, Hardy, Linda, Lagasse, Alex, Moreira, Ana Rita Silva, Bird, Jordan, Thomas, Christian L, Avaritt, Nathan, Kharas, Michael G, Lengner, Christopher J, Byrum, Stephanie D, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M

“…Abstract The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in…”
Get full text

OR08-2 Functional Association of the Stem Cell Protein Musashi With LSM14B in Control of mRNA Translation by Banik, Jewel, Bronson, Katherine, Childs, Gwen, Hardy, Linda, Lim, Juchan, MacNicol, Melanie, MacNicol, Angus

“…Abstract The Musashi RNA-binding protein functions as a gatekeeper of cell maturation and maintains stem cell plasticity by regulating the translation of…”
Get full text

PMON29 A Comparative Analysis of Musashi-Dependent Control of Mouse and Human Pituitary mRNA Translation by Banik, Jewel, Childs, Gwen, Hardy, Linda, MacNicol, Angus, MacNicol, Melanie, Tomlinson, Sophia

“…Abstract Specialized cell lineages within the anterior pituitary produce specific hormones which, in turn, regulate diverse biological processes ranging from…”
Get full text

Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression by Odle, Angela K, Beneš, Helen, Melgar Castillo, Andrea, Akhter, Noor, Syed, Mohsin, Haney, Anessa, Allensworth-James, Melody, Hardy, Linda, Winter, Benjamin, Manoharan, Ragul, Syed, Raiyan, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Abstract The cyclic expression of pituitary gonadotropin-releasing hormone receptors (GnRHRs) may be an important checkpoint for leptin regulatory signals…”
Get full text

RF01 | PMON46 Regulation of the Pituitary Cell Lineage Regulator Prop1 by the Stem Cell Determinant Musashi by Banik, Jewel, Childs, Gwen V, Hardy, Linda L, Lim, Juchan, MacNicol, Angus M, MacNicol, Melanie C, Tomlinson, Sophia, Urbaniak, Alicja

“…Abstract The pituitary gland controls responses to changing physiological requirements during growth, pregnancy, puberty, and stress. Synthesis and secretion…”
Get full text

The Cell Fate Determinant Musashi Is Controlled Through Dynamic Protein:Protein Interactions by Bronson, Katherine, Balasubramaniam, Meenakshisundaram, Hardy, Linda, Childs, Gwen V, MacNicol, Melanie C, MacNicol, Angus M

“…Abstract The Musashi RNA-binding protein functions as a gatekeeper of cell maturation and plasticity through the control of target mRNA translation. It is…”
Get full text

Transforming care strategies and nursing-sensitive patient outcomes by Chaboyer, Wendy, Johnson, Joanne, Hardy, Linda, Gehrke, Tanya, Panuwatwanich, Kriengsak

“…chaboyer w., johnson j., hardy l., gehrke t. & panuwatwanich k. (2010)  Transforming care strategies and nursing‐sensitive patient outcomes. Journal of…”
Get full text

RF25 | PMON50 Insight into Integrated Control of Pituitary Function Revealed Through Analysis of Musashi Target mRNAs by Lim, Juchan, Banik, Jewel, Urbaniak, Alicja, Bronson, Katherine, Tomlinson, Sophia, Hardy, Linda, Gies, Allen, Byrum, Stephanie, Wilczynska, Ania, MacNicol, Melanie, Childs, Gwen, MacNicol, Angus

“…Abstract The anterior pituitary controls growth, metabolism, reproduction and stress responses through the synthesis and secretion of specific hormones…”
Get full text

The Musashi1 RNA-Binding Protein Functions as a Leptin-Regulated Enforcer of Pituitary Cell Fate and Hormone Production by Banik, Jewel, Lim, Juchan, Linda, Hardy L, Odle, Angela Katherine, Childs, Gwen V, MacNicol, Melanie C, MacNicol, Angus M

“…Abstract The pituitary gland is the major endocrine organ that produces and secretes hormones in response to hypothalamic signals to regulate important…”
Get full text