Search Results - "Hardtke, M."

Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC‐Specific Chimeric Antigen Receptor by Noyan, F., Zimmermann, K., Hardtke‐Wolenski, M., Knoefel, A., Schulde, E., Geffers, R., Hust, M., Huehn, J., Galla, M., Morgan, M., Jokuszies, A., Manns, M. P., Jaeckel, E.

“…CD4+CD25highFOXP3+ regulatory T cells (Tregs) are involved in graft‐specific tolerance after solid organ transplantation. However, adoptive transfer of…”
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Safety and efficacy of BAY 94‐9027, a prolonged‐half‐life factor VIII by Reding, M. T., Ng, H. J., Poulsen, L. H., Eyster, M. E., Pabinger, I., Shin, H.‐J., Walsch, R., Lederman, M., Wang, M., Hardtke, M., Michaels, L. A.

“…Essentials Recombinant factor VIII BAY 94‐9027 conjugates in a site‐specific manner with polyethylene glycol. BAY 94‐9027 was given to patients with severe…”
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TRUST trial: BAY 86-6150 use in haemophilia with inhibitors and assessment for immunogenicity by Mahlangu, J., Paz, P., Hardtke, M., Aswad, F., Schroeder, J.

“…Introduction The most serious and challenging complication of haemophilia treatment is development of inhibitors to replacement factors VIII or IX. Innovative…”
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Enrichment of Regulatory T Cells in Acutely Rejected Human Liver Allografts by Taubert, R., Pischke, S., Schlue, J., Wedemeyer, H., Noyan, F., Heim, A., Lehner, F., Barg‐Hock, H., Klempnauer, J., Olek, S., Manns, M. P., Hardtke‐Wolenski, M., Jaeckel, E.

“…Acute cellular rejection (ACR) occurs frequently after liver transplantation and can usually be controlled. Triggering of allospecific immune responses and…”
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Naive Tumour‐Specific CD4+ T Cells were Efficiently Primed in Acute Lymphoblastic Leukaemia by Noyan, F., Lieke, T., Taubert, R., Sievers, M., Dywicki, J., Hapke, M., Falk, C. S., Manns, M. P., Jaeckel, E., Hardtke‐Wolenski, M.

“…The recognition and neutralization of tumour cells is one of the big challenges in immunity. The immune system has to recognize syngeneic tumour cells and has…”
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New GLP-1 agonist dulaglutide improves metabolic dysfunction and extenuates development of non-acoholic steatohepatitis in mice by Hupa, K.L, Hardtke-Wolenski, M, Manns, M.P, Jaeckel, E

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Preferential Accumulation of Graft Infiltrating T Helper Cells but Not Cytotoxic T Cells Distinguishes Subclinical Rejection from Acute Cellular Rejection in Human Liver Allografts by Taubert, R, Baumann, A, Noyan, F, Hardtke-Wolenski, M, Schlue, J, Lehner, F, Manns, M, Jaeckel, E

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Operational tolerance in allotransplantation by use of regulatory T cells with a MHC-specific chimeric antigen receptor by Noyan, F, Zimmermann, K, Hardtke-Wolenski, M, Knoefl, A, Schulde, E, Geffers, R, Hust, M, Huehn, J, Galla, M, Morgan, M, Jokuszies, A, Manns, M.P, Jaeckel, E

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P349 INTRAHEPATIC REGULATORY T CELLS ARE ASSOCIATED WITH TREATMENT RESPONSE IN AUTOIMMUNE HEPATITIS TYPE 1 AND ARE DEPLETED WITH CURRENT THERAPIES by Taubert, R, Hardtke-Wolenski, M, Noyan, F, Wilms, A, Baumann, A.K, Schlue, J, Olek, S, Manns, M.P, Jaeckel, E

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Donor-specific Regulatory T Cells Generated on Donor B Cells Are Superior to CD4+CD25high Cells in Controlling Alloimmune Responses in Humanized Mice by Noyan, F, Lee, Y.-S, Hardtke-Wolenski, M, Knoefel, A.-K, Taubert, R, Baron, U, Manns, M.P, Jaeckel, E

“…Abstract CD4+ CD25highFOXP3+ regulatory T cells (Tregs) can control allospecific immune responses in vitro and in titrated lymphopenic transplantation models…”
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Hormone withdrawal-associated symptoms with ethinylestradiol 20 µg/drospirenone 3 mg (24/4 regimen) versus ethinylestradiol 20 µg/desogestrel 150 µg (21/7 regimen) by Bitzer, Johannes, Banal-Silao, Maria Jesusa, Ahrendt, Hans-Joachim, Restrepo, Jaime, Hardtke, Marion, Wissinger-Graefenhahn, Ulrike, Trummer, Dietmar

“…Objective: To assess whether the combined oral contraceptive (COC) ethinylestradiol (EE) 20 µg/drospirenone 3 mg taken in a 24/4-day regimen (ie, 4-day…”
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FRI-359 - New GLP-1 agonist dulaglutide improves metabolic dysfunction and extenuates development of non-acoholic steatohepatitis in mice by Hupa, K.L., Hardtke-Wolenski, M., Manns, M.P., Jaeckel, E.

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Long-Lasting Imprint in the Soluble Inflammatory Milieu Despite Early Treatment of Acute Symptomatic Hepatitis C by Khera, Tanvi, Du, Yanqin, Todt, Daniel, Deterding, Katja, Strunz, Benedikt, Hardtke, Svenja, Aregay, Amare, Port, Kerstin, Hardtke-Wolenski, Matthias, Steinmann, Eike, Björkström, Niklas K, Manns, Michael P, Hengst, Julia, Cornberg, Markus, Wedemeyer, Heiner

“…Abstract Background Treatment with direct-acting antivirals (DAAs) in patients with chronic hepatitis C infection leads to partial restoration of soluble…”
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Immune complexes and antibodies to BCG in sera from patients with mycobacterial infections by Carr, R I, Chakraborty, A K, Brunda, M J, Davidson, P T, Damle, P B, Hardtke, M A, Gilbride, K J, Minden, P

“…We have examined the prevalence of circulating immune complexes in sera from patients with mycobacterial infections. Sera from 68 percent of patients with…”
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The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B virus infection by Du, Yanqin, Anastasiou, Olympia E., Strunz, Benedikt, Scheuten, Janina, Bremer, Birgit, Kraft, Anke, Kleinsimglinhaus, Karolina, Todt, Daniel, Broering, Ruth, Hardtke‐Wolenski, Matthias, Wu, Jun, Yang, Dongliang, Dittmer, Ulf, Lu, Mengji, Cornberg, Markus, Björkström, Niklas K., Khera, Tanvi, Wedemeyer, Heiner

“…Background & Aims During chronic hepatitis B virus (HBV) infection, suppressed functionality of natural killer (NK) cells might contribute to HBV persistence…”
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FRI-480 - Preferential Accumulation of Graft Infiltrating T Helper Cells but Not Cytotoxic T Cells Distinguishes Subclinical Rejection from Acute Cellular Rejection in Human Liver Allografts by Taubert, R., Baumann, A., Noyan, F., Hardtke-Wolenski, M., Schlue, J., Lehner, F., Manns, M., Jaeckel, E.

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PS-068 - Operational tolerance in allotransplantation by use of regulatory T cells with a MHC-specific chimeric antigen receptor by Noyan, F., Zimmermann, K., Hardtke-Wolenski, M., Knoefl, A., Schulde, E., Geffers, R., Hust, M., Huehn, J., Galla, M., Morgan, M., Jokuszies, A., Manns, M.P., Jaeckel, E.

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Human Donor-Specific Tregs Can Prevent Allograft Rejection in Humanized Immune Reconstituted Mice: Abstract# 743 by Jaeckel, E., Hardtke-Wolenski, M., Lee, Y., Taubert, R., Warnecke, G., Knoefel, A., Manns, M., Noyan, F.

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Stable Alloantigen-Specific Regulatory T Cells Can Induce Tolerance after Allogeneic Transplantation: 1625 by Seltrecht, N., Mpofu, N., Hardtke-Wolenski, M., Noyan, F., Manns, M., Jaeckel, E.

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Orally induced tolerance to casein in mice on normal mouse chow by Carr, R I, Hardtke, M A, Katilus, J, Sadi, D

“…We examined the ability of bovine casein to induce oral tolerance in BDF1 mice raised on a normal mouse chow diet. Giving 20 mg casein 1 X or 4 X by…”
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