Search Results - "Hardt, Katja"

PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells by Lee, Sophia Boyoung, Doberstein, Kai, Baumgarten, Peter, Wieland, Anja, Ungerer, Christopher, Bürger, Claudia, Hardt, Katja, Boehncke, Wolf-Henning, Pfeilschifter, Josef, Mihic-Probst, Daniela, Mittelbronn, Michel, Gutwein, Paul

“…PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and…”
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Activators of Peroxisome Proliferator-Activated Receptors Protect Human Skin from Ultraviolet-B-Light-Induced Inflammation by Kippenberger, Stefan, Grundmann-Kollmann, Marcella, Simon, Stephanie, Dang, Tu-Anh, Hardt-Weinelt, Katja, Kaufmann, Roland, Bernd, August, Loitsch, Stefan Marcel

“…Peroxisome proliferator-activated receptors (PPAR) are members of a nuclear receptor superfamily, which were initially described in the context of fatty acid…”
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Interleukin-1β Interferes with Epidermal Homeostasis through Induction of Insulin Resistance: Implications for Psoriasis Pathogenesis by Buerger, Claudia, Richter, Beatrice, Woth, Kathrin, Salgo, Rebekka, Malisiewicz, Bartosz, Diehl, Sandra, Hardt, Katja, Boehncke, Sandra, Boehncke, Wolf-Henning

“…Response pathways of the metabolic and the immune system have been evolutionary conserved, resulting in a high degree of integrated regulation. Insulin is a…”
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Systemic therapy of plaque-type psoriasis ameliorates endothelial cell function: results of a prospective longitudinal pilot trial by Boehncke, Sandra, Fichtlscherer, Stephan, Salgo, Rebekka, Garbaraviciene, Jurate, Beschmann, Heike, Diehl, Sandra, Hardt, Katja, Thaçi, Diamant, Boehncke, Wolf-Henning

“…Severe psoriasis is associated with significant cardiovascular mortality. We therefore investigated the effects of systemic therapy on the cardiovascular risk…”
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Endogenous μ-opioid peptides modulate immune response towards malignant melanoma by Boehncke, Sandra, Hardt, Katja, Schadendorf, Dirk, Henschler, Reinhard, Boehncke, Wolf-Henning, Duthey, Beatrice

“…:  Opioids exert major effects not only in the central nervous system but also in immune responses. We investigated the effects of μ‐opioid peptides, secreted…”
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Dimethylfumarate Reduces Leukocyte Rolling in Vivo through Modulation of Adhesion Molecule Expression by Rubant, Simone A., Ludwig, Ralf J., Diehl, Sandra, Hardt, Katja, Kaufmann, Roland, Pfeilschifter, Josef M., Boehncke, Wolf-Henning

“…Esters of fumaric acid have a long tradition in the treatment of psoriasis. Dimethylfumarate (DMF) is perceived as the main active substance. However, the…”
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Interleukin-1[beta] Interferes with Epidermal Homeostasis through Induction of Insulin Resistance: Implications for Psoriasis Pathogenesis by Buerger, Claudia, Richter, Beatrice, Woth, Kathrin, Salgo, Rebekka, Malisiewicz, Bartosz, Diehl, Sandra, Hardt, Katja, Boehncke, Sandra, Boehncke, Wolf-henning

“…Response pathways of the metabolic and the immune system have been evolutionary conserved, resulting in a high degree of integrated regulation. Insulin is a…”
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ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma by Ungerer, Christopher, Doberstein, Kai, Bürger, Claudia, Hardt, Katja, Boehncke, Wolf-Henning, Böhm, Beate, Pfeilschifter, Josef, Dummer, Reinhard, Mihic-Probst, Daniela, Gutwein, Paul

“…► Strong ADAM15 expression is found in normal melanocytes. ► ADAM15 expression is significantly downregulated in patients with melanoma metastasis. ► TGF-β can…”
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Junctional adhesion molecule (JAM)‐B supports lymphocyte rolling and adhesion through interaction with α4β1 integrin by Ludwig, Ralf J., Hardt, Katja, Hatting, Max, Bistrian, Roxana, Diehl, Sandra, Radeke, Heinfried H., Podda, Maurizio, Schön, Michael P., Kaufmann, Roland, Henschler, Reinhard, Pfeilschifter, Josef M., Santoso, Sentot, Boehncke, Wolf‐Henning

“…Summary Junctional adhesion molecule‐A (JAM‐A), JAM‐B and JAM‐C have been implicated in leucocyte transmigration. As JAM‐B binds to very late activation…”
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Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha 4 beta 1 integrin by Ludwig, Ralf J, Hardt, Katja, Hatting, Max, Bistrian, Roxana, Diehl, Sandra, Radeke, Heinfried H, Podda, Maurizio, Schoen, Michael P, Kaufmann, Roland, Henschler, Reinhard, Pfeilschifter, Josef M, Santoso, Sentot, Boehncke, Wolf-Henning

“…SummaryJunctional adhesion molecule-A (JAM-A), JAM-B and JAM-C have been implicated in leucocyte transmigration. As JAM-B binds to very late activation antigen…”
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Junctional Adhesion Molecules (JAM)-B and -C Contribute to Leukocyte Extravasation to the Skin and Mediate Cutaneous Inflammation by Ludwig, Ralf J., Zollner, Thomas M., Santoso, Sentot, Hardt, Katja, Gille, Jens, Baatz, Holger, Johann, Petra Schulze, Pfeffer, Jeannette, Radeke, Heinfried H., Schön, Michael P., Kaufmann, Roland, Boehncke, Wolf-Henning, Podda, Maurizio

“…Leukocyte extravasation is a finely tuned process, in which transmigration is the final step. Transmigration depends on molecules located at borders of…”
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Endogenous μ-opioid peptides modulate immune response towards malignant melanoma: Endogenous μ-opioid peptides modulate immune response by Boehncke, Sandra, Hardt, Katja, Schadendorf, Dirk, Henschler, Reinhard, Boehncke, Wolf-Henning, Duthey, Beatrice

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Platelet, Not Endothelial, P-Selectin Expression Contributes to Generation of Immunity in Cutaneous Contact Hypersensitivity by Ludwig, Ralf J, Bergmann, Peri, Garbaraviciene, Jurate, Stebut, Esther von, Radeke, Heinfried H, Gille, Jens, Diehl, Sandra, Hardt, Katja, Henschler, Reinhard, Kaufmann, Roland, Pfeilschifter, Josef M, Boehncke, Wolf-Henning

“…Leukocyte extravasation is a prerequisite for host defense and autoimmunity alike. Detailed understanding of the tightly controlled and overlapping sequences…”
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Constitutive and functionally relevant expression of JAM-C on platelets by Erpenbeck, Luise, Rubant, Simone, Hardt, Katja, Santoso, Sentot, Boehncke, Wolf-Henning, Schön, Michael P, Ludwig, Ralf J

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Spatial distribution of 8‐methoxypsoralen penetration into human skin after systemic or topical administration by Grundmann‐Kollmann, Marcella, Podda, Maurizio, Bräutigam, Lutz, Hardt‐Weinelt, Katja, Ludwig, Ralf J., Geisslinger, Gerd, Kaufmann, Roland, Tegeder, Irmgard

“…Aims  Photochemotherapy employing psoralens combined with UVA irradiation (PUVA) is a standard therapy for a variety of dermatoses. Psoralens can be…”
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Pharmacological and histopathological characterization of a hyperalgesia model induced by freeze lesion by Schmidtko, Achim, Burian, Maria, Altis, Kosta, Hardt, Katja, Angioni, Carlo, Schmidt, Ronald, Podda, Maurizio, Geisslinger, Gerd

“…Induction of a freeze lesion in human skin is an experimental model of hyperalgesia that allows assessing the antihyperalgesic effects of traditional…”
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Oligonucleotides suppress IL-8 in skin keratinocytes In Vitro and offer anti-inflammatory properties In Vivo. Commentary by PIVARCS, Andor, DORN, Annette, LUDWIG, Ralf Joachim, BOCK, Andreas, THACI, Diamant, HARDT, Katja, BEREITER-HAHN, Jürgen, KAUFMANN, Roland, BERND, August, KIPPENBERGER, Stefan

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Computer-aided analysis of cell interactions under dynamic flow conditions by Giegold, Oliver, Ludwig, Ralf J., Hardt, Katja, Will, Jutta, Schön, Michael P., Oostingh, Gertie J., Pfeilschifter, Josef M., Boehncke, Wolf-Henning, Radeke, Heinfried H.

“…:  Experimentally, initial steps of leucocyte extravasation, including tethering and rolling, are analysed in endothelial cell flow chambers. Given the…”
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Oligonucleotides Suppress IL-8 in Skin Keratinocytes In Vitro and Offer Anti-Inflammatory Properties In Vivo by Dorn, Annette, Ludwig, Ralf Joachim, Bock, Andreas, Thaci, Diamant, Hardt, Katja, Bereiter-Hahn, Jurgen, Kaufmann, Roland, Bernd, August, Kippenberger, Stefan

“…DNA codes for genetic information. Furthermore, recent findings suggest that DNA offers additional function, particularly in the recognition of microorganisms…”
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Eosinophilic cellulitis (Wells' syndrome) associated with colon carcinoma by Hirsch, Katrin, Ludwig, Ralf J., Wolter, Manfred, Zollner, Thomas M., Hardt, Katja, Kaufmann, Roland, Boehncke, Wolf-Henning

“…Summary Eosinophilic cellulitis (Wells' syndrome) is an inflammatory dermatosis characterized by marked eosinophilic infiltrates. Drugs and various infections…”
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