Search Results - "Hardt, E"

Longitudinal Left Ventricular Function for Prediction of Survival in Systemic Light-Chain Amyloidosis by Buss, Sebastian J., MD, Emami, Mostafa, BSc, Mereles, Derliz, MD, Korosoglou, Grigorios, MD, Kristen, Arnt V., MD, Voss, Andreas, PhD, Schellberg, Dieter, PhD, Zugck, Christian, MD, Galuschky, Christian, MS, Giannitsis, Evangelos, MD, Hegenbart, Ute, MD, Ho, Anthony D., MD, Katus, Hugo A., MD, Schonland, Stefan O., MD, Hardt, Stefan E., MD

“…Objectives The aim of the study was to determine whether longitudinal left ventricular (LV) function provides prognostic information in a large cohort of…”
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Beneficial Effects of Mammalian Target of Rapamycin Inhibition on Left Ventricular Remodeling After Myocardial Infarction by Buss, Sebastian J., MD, Muenz, Sebastian, MD, Riffel, Johannes H., MD, Malekar, Pratima, PhD, Hagenmueller, Marco, PhD, Weiss, Celine S., MD, Bea, Florian, MD, Bekeredjian, Raffi, MD, Schinke-Braun, Martina, PhD, Izumo, Seigo, MD, PhD, Katus, Hugo A., MD, Hardt, Stefan E., MD

“…Objectives The extent of adverse myocardial remodeling contributes essentially to the prognosis after myocardial infarction (MI). In this study we investigated…”
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High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart by ANDRASSY, Martin, VOLZ, Hans C, BEA, Florian, HARDT, Stefan E, HUMPERT, Per M, BIANCHI, Marco E, MAIRBÄURL, Heimo, NAWROTH, Peter P, REMPPIS, Andrew, KATUS, Hugo A, BIERHAUS, Angelika, IGWE, John C, FUNKE, Benjamin, EICHBERGER, Sebastian N, KAYA, Ziya, BUSS, Sebastian, AUTSCHBACH, Frank, PLEGER, Sven T, LUKIC, Ivan K

“…High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic cells and by activated immune cells. HMGB1 signals via members of the toll-like…”
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The cardiac microenvironment uses non‐canonical WNT signaling to activate monocytes after myocardial infarction by Meyer, Ingmar Sören, Jungmann, Andreas, Dieterich, Christoph, Zhang, Min, Lasitschka, Felix, Werkmeister, Susann, Haas, Jan, Müller, Oliver J, Boutros, Michael, Nahrendorf, Matthias, Katus, Hugo A, Hardt, Stefan E, Leuschner, Florian

“…A disturbed inflammatory response following myocardial infarction (MI) is associated with poor prognosis and increased tissue damage. Monocytes are key players…”
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Wnt Signaling Is Critical for Maladaptive Cardiac Hypertrophy and Accelerates Myocardial Remodeling by Malekar, Pratima, Hagenmueller, Marco, Anyanwu, Adamma, Buss, Sebastian, Streit, Marcus R, Weiss, Celine S, Wolf, David, Riffel, Johannes, Bauer, Alexander, Katus, Hugo A, Hardt, Stefan E

“…The evolutionary conserved Wnt signaling pathway regulates cardiogenesis. However, members of the Wnt pathway are also expressed in the adult heart. Although…”
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n-type Ge/Si antennas for THz sensing by Chavarin, C A, Hardt, E, Gruessing, S, Skibitzki, O, Costina, I, Spirito, D, Seifert, W, Klesse, W, Manganelli, C L, You, C, Flesch, J, Piehler, J, Missori, M, Baldassarre, L, Witzigmann, B, Capellini, G

“…Ge-on-Si plasmonics holds the promise for compact and low-cost solutions in the manipulation of THz radiation. We discuss here the plasmonic properties of…”
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Elucidating a Magnetic Resonance Imaging-Based Neuroanatomic Biomarker for Psychosis: Classification Analysis Using Probabilistic Brain Atlas and Machine Learning Algorithms by Sun, Daqiang, van Erp, Theo G.M, Thompson, Paul M, Bearden, Carrie E, Daley, Melita, Kushan, Leila, Hardt, Molly E, Nuechterlein, Keith H, Toga, Arthur W, Cannon, Tyrone D

“…Background No objective diagnostic biomarkers or laboratory tests have yet been developed for psychotic illness. Magnetic resonance imaging (MRI) studies…”
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Dapper-1 is essential for Wnt5a induced cardiomyocyte hypertrophy by regulating the Wnt/PCP pathway by Hagenmueller, Marco, Riffel, Johannes H., Bernhold, Elmar, Fan, Jingjing, Katus, Hugo A., Hardt, Stefan E.

“…•Wnt5a stimulation induces cardiomyocyte hypertrophy.•Knockdown of Dpr1 blocks Wnt5a induced cardiomyocyte hypertrophy.•Dpr1 is required for Wnt5a mediated…”
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Glycogen Synthase Kinase-3β: A Novel Regulator of Cardiac Hypertrophy and Development by Hardt, Stefan E, Sadoshima, Junichi

“…Glycogen synthase kinase-3β (GSK-3β) is a ubiquitously expressed constitutively active serine/threonine kinase that phosphorylates cellular substrates and…”
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Anterior Aortic Plane Systolic Excursion: A Novel Indicator of Transplant-Free Survival in Systemic Light-Chain Amyloidosis by Ochs, Marco M., MD, Riffel, Johannes, MD, Kristen, Arnt V., PhD, Hegenbart, Ute, PhD, Schönland, Stefan, PhD, Hardt, Stefan E., PhD, Katus, Hugo A., PhD, Mereles, Derliz, MD, Buss, Sebastian J., PhD

“…Background Anterior aortic plane systolic excursion (AAPSE) was evaluated in the present pilot study as a novel echocardiographic indicator of transplant-free…”
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Impact of Homoarginine on Myocardial Function and Remodeling in a Rat Model of Chronic Renal Failure by Koch, Vitali, Weber, Christophe, Riffel, Johannes H., Buchner, Kristina, Buss, Sebastian J., Hein, Selina, Mereles, Derliz, Hagenmueller, Marco, Erbel, Christian, März, Winfried, Booz, Christian, Albrecht, Moritz H., Vogl, Thomas J., Frey, Norbert, Hardt, Stefan E., Ochs, Marco

“…Purpose: Low plasma concentrations of the amino acid homoarginine (HA) have been shown to correlate with adverse cardiovascular outcome, particularly in…”
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Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling by Lehmann, Lorenz H., Rostosky, Julia S., Buss, Sebastian J., Kreusser, Michael M., Krebs, Jutta, Mier, Walter, Enseleit, Frank, Spiger, Katharina, Hardt, Stefan E., Wieland, Thomas, Haass, Markus, Lüscher, Thomas F., Schneider, Michael D., Parlato, Rosanna, Gröne, Hermann-Josef, Haberkorn, Uwe, Yanagisawa, Masashi, Katus, Hugo A., Backs, Johannes

“…Significance In failing hearts, norepinephrine (NE) net release and endothelin-1 (ET1) levels are increased. ET1 receptor antagonists were successfully used in…”
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Dapper-1 Induces Myocardial Remodeling Through Activation of Canonical Wnt Signaling in Cardiomyocytes by Hagenmueller, Marco, Riffel, Johannes H, Bernhold, Elmar, Fan, Jingjing, Zhang, Min, Ochs, Marco, Steinbeisser, Herbert, Katus, Hugo A, Hardt, Stefan E

“…Heart failure has an increasing contribution to cardiovascular disease burden and is governed by the myocardial remodeling process. The contribution of Wnt…”
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Myocardial Left Ventricular Dysfunction in Patients with Systemic Lupus Erythematosus: New Insights from Tissue Doppler and Strain Imaging by BUSS, Sebastian J, WOLF, David, KATUS, Hugo A, HARDT, Stefan E, HANSEN, Alexander, KOROSOGLOU, Grigorios, MAX, Regina, WEISS, Celine S, FISCHER, Christian, SCHELLBERG, Dieter, ZUGCK, Christian, KUECHERER, Helmut F, LORENZ, Hanns-Martin

“…Objective. Systemic lupus erythematosus (SLE) is associated with high cardiovascular morbidity and mortality. Cardiovascular involvement is frequently…”
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Negative regulators of cardiac hypertrophy by HARDT, Stefan E, SADOSHIMA, Junichi

“…Throughout the past decade, much effort has been spent on deciphering the signaling pathways positively mediating cardiac hypertrophy. Recently, several…”
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Rapid assessment of longitudinal systolic left ventricular function using speckle tracking of the mitral annulus by Buss, Sebastian J., Mereles, Derliz, Emami, Mostafa, Korosoglou, Grigorios, Riffel, Johannes H., Bertel, Diane, Schonland, Stefan O., Hegenbart, Ute, Katus, Hugo A., Hardt, Stefan E.

“…Background Evaluation of left ventricular function (LV) is one of the most important tasks of echocardiography. Left ventricular longitudinal function has been…”
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Cardiac Effects of Attenuating Gsα - Dependent Signaling by Streit, Marcus R, Weiss, Celine S, Meyer, Sören, Ochs, Marco M, Hagenmueller, Marco, Riffel, Johannes H, Buss, Sebastian J, Heger, Thomas, Katus, Hugo A, Hardt, Stefan E

“…Inhibition of β-adrenergic signalling plays a key role in treatment of heart failure. Gsα is essential for β-adrenergic signal transduction. In order to reduce…”
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DYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3β on eIF2Bε by Weiss, Celine S, Ochs, Marco M, Hagenmueller, Marco, Streit, Marcus R, Malekar, Pratima, Riffel, Johannes H, Buss, Sebastian J, Weiss, Karl H, Sadoshima, Junichi, Katus, Hugo A, Hardt, Stefan E

“…A prerequisite of hypertrophic response of the myocardium is an increase in protein synthesis. A central regulator of translation initiation is Eukaryotic…”
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Closure of patent foramen ovale defects using GORE® CARDIOFORM septal occluder: Results from a prospective European multicenter study by Hardt, Stefan E., Eicken, Andreas, Berger, Felix, Schubert, Stephan, Carminati, Mario, Butera, Gianfranco, Grohmann, Jochen, Höhn, Rene, Nielsen‐Kudsk, Jens Erik, Hildick‐Smith, David, Settergren, Magnus, Thomson, John D., Geis, Nicolas, Søndergaard, Lars

“…Aims The GORE® CARDIOFORM Septal Occluder (GSO) is a novel device designed for rapid and effective closure of patent foramen ovale (PFO) which has distinctive…”
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Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters by Buss, Sebastian J., Riffel, Johannes H., Katus, Hugo A., Hardt, Stefan E.

“…The extent of adverse myocardial remodeling contributes essentially to the prognosis after myocardial infarction (MI). Currently, therapeutic strategies that…”
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