Search Results - "Harding, M."

Uncovering the mechanisms of Acinetobacter baumannii virulence by Harding, Christian M., Hennon, Seth W., Feldman, Mario F.

“…Key Points Acinetobacter baumannii is an opportunistic human pathogen that predominantly causes health-care-associated infections. Many members of the genus…”
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Mitotic progression following DNA damage enables pattern recognition within micronuclei by Harding, Shane M., Benci, Joseph L., Irianto, Jerome, Discher, Dennis E., Minn, Andy J., Greenberg, Roger A.

“…The authors report a link between mitosis, the formation of micronuclei and DNA-damage-induced cGAS-dependent inflammation. Cell cycle effects of combined…”
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Quasi-Particle Self-Consistent GW for Molecules by Kaplan, F, Harding, M. E, Seiler, C, Weigend, F, Evers, F, van Setten, M. J

“…We present the formalism and implementation of quasi-particle self-consistent GW (qsGW) and eigenvalue only quasi-particle self-consistent GW (evGW) adapted to…”
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AASM Scoring Manual Updates for 2017 (Version 2.4) by Berry, Richard B, Brooks, Rita, Gamaldo, Charlene, Harding, Susan M, Lloyd, Robin M, Quan, Stuart F, Troester, Matthew T, Vaughn, Bradley V

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Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae by Wantuch, Paeton L, Knoot, Cory J, Robinson, Lloyd S, Vinogradov, Evgeny, Scott, Nichollas E, Harding, Christian M, Rosen, David A

“…Klebsiella pneumoniae presents as two circulating pathotypes: classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp). Classical isolates are…”
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ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition by Harding, Shane M., Boiarsky, Jonathan A., Greenberg, Roger A.

“…Resolution of DNA double-strand breaks (DSBs) is essential for the suppression of genome instability. DSB repair in transcriptionally active genomic regions…”
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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities by Shibata, Atsushi, Moiani, Davide, Arvai, Andrew S., Perry, Jefferson, Harding, Shane M., Genois, Marie-Michelle, Maity, Ranjan, van Rossum-Fikkert, Sari, Kertokalio, Aryandi, Romoli, Filippo, Ismail, Amani, Ismalaj, Ermal, Petricci, Elena, Neale, Matthew J., Bristow, Robert G., Masson, Jean-Yves, Wyman, Claire, Jeggo, Penny A., Tainer, John A.

“…MRE11 within the MRE11-RAD50-NBS1 (MRN) complex acts in DNA double-strand break repair (DSBR), detection, and signaling; yet, how its endo- and exonuclease…”
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DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration by Irianto, Jerome, Xia, Yuntao, Pfeifer, Charlotte R., Athirasala, Avathamsa, Ji, Jiazheng, Alvey, Cory, Tewari, Manu, Bennett, Rachel R., Harding, Shane M., Liu, Andrea J., Greenberg, Roger A., Discher, Dennis E.

“…Migration through micron-size constrictions has been seen to rupture the nucleus, release nuclear-localized GFP, and cause localized accumulations of ectopic…”
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Characteristics of wastewater originating from dental practices using predominantly mercury-free dental materials by Binner, H., Kamali, N., Harding, M., Sullivan, T.

“…Dental materials are currently undergoing a revolution. Mercury use, including traditional amalgam (mercury-containing) material used in dental fillings, is…”
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In-situ time resolved spectrographic measurement using an additively manufactured metallic micro-fluidic analysis platform by Monaghan, T W, Harding, M J, Christie, S D R, Friel, R J

“…Microfluidic reactionware allows small volumes of reagents to be utilized for highly controlled flow chemistry applications. By integrating these microreactors…”
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Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses by Chen, Jie, Harding, Shane M., Natesan, Ramakrishnan, Tian, Lei, Benci, Joseph L., Li, Weihua, Minn, Andy J., Asangani, Irfan A., Greenberg, Roger A.

“…The DNA-dependent pattern recognition receptor, cGAS (cyclic GMP-AMP synthase), mediates communication between the DNA damage and the immune responses. Mitotic…”
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New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class by Selezneva, Anna I, Harding, Luke N M, Gutka, Hiten J, Movahedzadeh, Farahnaz, Abad-Zapatero, Celerino

“…Class II Fructose-1,6-bisphosphatases (FBPaseII) (EC: 3.1.3.11) are highly conserved essential enzymes in the gluconeogenic pathway of microorganisms. Previous…”
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Frequency-comb spectroscopy on pure quantum states of a single molecular ion by Chou, C W, Collopy, A L, Kurz, C, Lin, Y, Harding, M E, Plessow, P N, Fortier, T, Diddams, S, Leibfried, D, Leibrandt, D R

“…Spectroscopy is a powerful tool for studying molecules and is commonly performed on large thermal molecular ensembles that are perturbed by motional shifts and…”
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Genomic islands: tools of bacterial horizontal gene transfer and evolution by Juhas, Mario, van der Meer, Jan Roelof, Gaillard, Muriel, Harding, Rosalind M, Hood, Derek W, Crook, Derrick W

“…Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer. Besides the core genes encoding essential metabolic functions,…”
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Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei by MacDonald, Kate M., Nicholson-Puthenveedu, Shirony, Tageldein, Maha M., Khasnis, Sarika, Arrowsmith, Cheryl H., Harding, Shane M.

“…Micronuclei (MN) are cytosolic bodies that sequester acentric fragments or mis-segregated chromosomes from the primary nucleus. Spontaneous rupture of the MN…”
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AASM Scoring Manual Version 2.2 Updates: New Chapters for Scoring Infant Sleep Staging and Home Sleep Apnea Testing by Berry, Richard B, Gamaldo, Charlene E, Harding, Susan M, Brooks, Rita, Lloyd, Robin M, Vaughn, Bradley V, Marcus, Carole L

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The architecture of metal coordination groups in proteins by Harding, Marjorie M.

“…A set of tables is presented and a survey given of the architecture of metal coordination groups in a representative set of protein structures from the Protein…”
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A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host by Harding, Christian M., Nasr, Mohamed A., Scott, Nichollas E., Goyette-Desjardins, Guillaume, Nothaft, Harald, Mayer, Anne E., Chavez, Sthefany M., Huynh, Jeremy P., Kinsella, Rachel L., Szymanski, Christine M., Stallings, Christina L., Segura, Mariela, Feldman, Mario F.

“…Chemical synthesis of conjugate vaccines, consisting of a polysaccharide linked to a protein, can be technically challenging, and in vivo bacterial…”
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Community-level trachoma ecological associations and the use of geospatial analysis methods: A systematic review by Burgert-Brucker, Clara R, Adams, Molly W, Mingkwan, Pia, Flueckiger, Rebecca, Ngondi, Jeremiah M, Solomon, Anthony W, Harding-Esch, Emma M

“…Trachoma is targeted for global elimination as a public health problem by 2030. Understanding individual, household, or community-associated factors that may…”
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Ultrasonic testing of thick and thin Inconel 625 alloys manufactured by laser powder bed fusion by Allam, A., Alfahmi, O., Patel, H., Sugino, C., Harding, M., Ruzzene, M., Erturk, A.

“…Additive manufacturing of alloys enables low-volume production of functional metallic components with complex geometries. Ultrasonic testing can ensure the…”
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