Search Results - "Harding, K G"

Environmental analysis of plastic production processes: Comparing petroleum-based polypropylene and polyethylene with biologically-based poly-β-hydroxybutyric acid using life cycle analysis by Harding, K.G., Dennis, J.S., von Blottnitz, H., Harrison, S.T.L.

“…Polymers based on olefins have wide commercial applicability. However, they are made from non-renewable resources and are characterised by difficulty in…”
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Wound Dressings in Diabetic Foot Disease by Hilton, J. R., Williams, D. T., Beuker, B., Miller, D. R., Harding, K. G.

“…Wound dressings represent a part of the management of diabetic foot ulceration. Ideally, dressings should alleviate symptoms, provide wound protection, and…”
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sensitivity to honey of Gram-positive cocci of clinical significance isolated from wounds by Cooper, R.A, Molan, P.C, Harding, K.G

“…Aims: To determine the sensitivity to honey of Gram-positive cocci of clinical significance in wounds and demonstrate that inhibition is not exclusively due to…”
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Diagnosing Foot Infection in Diabetes by Williams, D. T., Hilton, J. R., Harding, K. G.

“…Infection represents the presence of an inflammatory response and tissue injury due to the interaction of the host with multiplying bacteria. The disease…”
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Alginates from wound dressings activate human macrophages to secrete tumour necrosis factor- α by Thomas, A, Harding, K.G, Moore, K

“…Alginates are used to manufacture a number of wound dressings. Clinical observations indicate that they may initiate or accelerate healing of chronic wounds…”
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Randomised controlled trial of the use of three dressing preparations in the management of chronic ulceration of the foot in diabetes by Jeffcoate, W J, Price, P E, Phillips, C J, Game, F L, Mudge, E, Davies, S, Amery, C M, Edmonds, M E, Gibby, O M, Johnson, A B, Jones, G R, Masson, E, Patmore, J E, Price, D, Rayman, G, Harding, K G

“…To determine the comparative effectiveness and cost-effectiveness of three dressing products, N-A, Inadine and Aquacel, for patients with diabetic foot ulcers,…”
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Science, Medicine, And The Future: Healing Chronic Wounds by Harding, K. G., Morris, H. L., Patel, G. K.

“…Greater interest in wound healing is needed to ensure higher standards of basic care. Precise identification of the systemic, local, and molecular factors…”
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Quantification of water usage at a South African platinum processing plant by Sheridan, C.M., Haggard, E.L., Harding, K.G.

“…The mining industry utilises 3% of the total water withdrawn in South Africa and is one of the industries responsible for the deterioration of water quality in…”
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Pathophysiology of chronic bacterial osteomyelitis. Why do antibiotics fail so often? by Ciampolini, J, Harding, K G

“…In this review the pathophysiology of chronic bacterial osteomyelitis is summarised, focusing on how bacteria succeed so often in overcoming both host defence…”
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Wound healing: potential therapeutic options by Bosanquet, D.C., Harding, K.G.

“…Summary This review highlights the range of therapeutic options available to clinicians treating difficult‐to‐heal wounds. While certain treatments are…”
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Antibacterial Activity of Honey against Strains of Staphylococcus Aureus from Infected Wounds by Cooper, R A, Molan, P C, Harding, K G

“…The antibacterial action of honey in infected wounds does not depend wholly on its high osmolality. We tested the sensitivity of 58 strains of…”
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Anaerobic cocci populating the deep tissues of chronic wounds impair cellular wound healing responses in vitro by Stephens, P., Wall, I.B., Wilson, M.J., Hill, K.E., Davies, C.E., Hill, C.M., Harding, K.G., Thomas, D.W.

“…Summary Background Anaerobic cocci are estimated to be present in the deep tissues of over 50% of chronic skin wounds. While the part they play in the…”
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Defective Extracellular Matrix Reorganization by Chronic Wound Fibroblasts is Associated with Alterations in TIMP-1, TIMP-2, and MMP-2 Activity by Cook, Helen, Stephens, Phil, Davies, K. June, Thomas, David W., Harding, Keith G.

“…Chronic leg wounds are characterized by defective remodeling of the extracellular matrix, failure of reepithelialization, and prolonged inflammation. The…”
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Topical steroids for chronic wounds displaying abnormal inflammation by Bosanquet, D C, Rangaraj, A, Richards, A J, Riddell, A, Saravolac, V M, Harding, K G

“…Chronic, non-healing wounds are often characterised by an excessive, and detrimental, inflammatory response. We review our experience of using a combined…”
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The role of lymphocytes in human dermal wound healing by BOYCE, D. E, JONES, W. D, RUGE, F, HARDING, K. G, MOORE, K

“…Animal experimental data indicate a requirement for functionally active T lymphocytes to allow optimal healing of dermal wounds. Little evidence exists to…”
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Development and validation of a gene expression test to identify hard‐to‐heal chronic venous leg ulcers by Bosanquet, D. C., Sanders, A. J., Ruge, F., Lane, J., Morris, C. A., Jiang, W. G., Harding, K. G.

“…Background Chronic venous leg ulcers pose a significant burden to healthcare systems, and predicting wound healing is challenging. The aim of this study was to…”
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The influence of exercise on foot perfusion in diabetes by Williams, D. T., Harding, K. G., Price, P. E.

“…Aims  Diabetic foot disease is associated with both macro‐ and microvascular disease. Exercise has both positive and negative effects on the perfusion of lower…”
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Causes and effects of the chronic inflammation in venous leg ulcers by Agren, M S, Eaglstein, W H, Ferguson, M W, Harding, K G, Moore, K, Saarialho-Kere, U K, Schultz, G S

“…The pathogenesis of venous leg ulcers is multifactorial. In this review article new physiological, molecular and cellular abnormalities in venous ulcers…”
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Healing of an MRSA-colonized, hydroxyurea-induced leg ulcer with honey by Natarajan, S, Williamson, D, Grey, J, Harding, KG, Cooper, RA

“…BACKGROUND: With the everincreasing emergence of antibiotic-resistant pathogens, in particular methicillin-resistant Staphylococcus aureus (MRSA) in leg…”
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An in vitro model of chronic wound biofilms to test wound dressings and assess antimicrobial susceptibilities by Hill, Katja E., Malic, Sladjana, McKee, Ruth, Rennison, Tracy, Harding, Keith G., Williams, David W., Thomas, David W.

“…Objectives The targeted disruption of biofilms in chronic wounds is an important treatment strategy and the subject of intense research. In the present study,…”
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