Search Results - "Harden, Nicholas"

Making the connection - shared molecular machinery and evolutionary links underlie the formation and plasticity of occluding junctions and synapses by Harden, Nicholas, Wang, Simon Ji Hau, Krieger, Charles

“…The pleated septate junction (pSJ), an ancient structure for cell-cell contact in invertebrate epithelia, has protein components that are found in three…”
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Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila by Harden, Nicholas

“…Wound healing in embryos and various developmental events in metazoans require the spreading and fusion of epithelial sheets. The complex signaling pathways…”
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Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function by Wang, Simon J H, Sinclair, Donald A R, Kim, Hae-Yoon, Kinsey, Stephen D, Yoo, Byoungjoo, Shih, Claire R Y, Wong, Kenneth K L, Krieger, Charles, Harden, Nicholas, Verheyen, Esther M

“…Homeodomain-interacting protein kinases (Hipks) have been previously associated with cell proliferation and cancer, however, their effects in the nervous…”
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CYFIP/Sra-1 Controls Neuronal Connectivity in Drosophila and Links the Rac1 GTPase Pathway to the Fragile X Protein by Schenck, Annette, Bardoni, Barbara, Langmann, Caillin, Harden, Nicholas, Mandel, Jean-Louis, Giangrande, Angela

“…Neuronal plasticity requires actin cytoskeleton remodeling and local protein translation in response to extracellular signals. Rho GTPase pathways control…”
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20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun by Yoo, Byoungjoo, Kim, Hae-Yoon, Chen, Xi, Shen, Weiping, Jang, Ji Sun, Stein, Shaianne N, Cormier, Olga, Pereira, Lionel, Shih, Claire R Y, Krieger, Charles, Reed, Bruce, Harden, Nicholas, Wang, Simon J H

“…Steroid hormones influence diverse biological processes throughout the animal life cycle, including metabolism, stress resistance, reproduction, and lifespan…”
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The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation by Bahri, Sami, Wang, Simon, Conder, Ryan, Choy, Juliana, Vlachos, Stephanie, Dong, Kevin, Merino, Carlos, Sigrist, Stephan, Molnar, Cristina, Yang, Xiaohang, Manser, Edward, Harden, Nicholas

“…Dorsal closure (DC) of the Drosophila embryo is a model for the study of wound healing and developmental epithelial fusions, and involves the sealing of a hole…”
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Modulation of morphogenesis by Egfr during dorsal closure in Drosophila by Shen, Weiping, Chen, Xi, Cormier, Olga, Cheng, David Chung-Pei, Reed, Bruce, Harden, Nicholas

“…During Drosophila embryogenesis the process of dorsal closure (DC) results in continuity of the embryonic epidermis, and DC is well recognized as a model…”
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Pak Functions Downstream of Dock to Regulate Photoreceptor Axon Guidance in Drosophila by Hing, Huey, Xiao, Jian, Harden, Nicholas, Lim, Louis, Zipursky, S.Lawrence

“…The SH2/SH3 adaptor protein Dock has been proposed to transduce signals from guidance receptors to the actin cytoskeleton in Drosophila photoreceptor (R cell)…”
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Heptanuclear and Decanuclear Manganese Complexes with the Anion of 2-Hydroxymethylpyridine by Harden, Nicholas C, Bolcar, Milissa A, Wernsdorfer, Wolfgang, Abboud, Khalil A, Streib, William E, Christou, George

“…The synthesis and magnetic properties are reported of two new clusters [Mn10O4(OH)2(O2CMe)8(hmp)8](ClO4)4 (1) and [Mn7(OH)3(hmp)9Cl3](Cl)(ClO4) (2). Complex 1…”
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New Insights from Drosophila into the Regulation of EGFR Signaling by Harden, Nicholas

“…Genetic analysis of Egfr signaling in Drosophila has a long-standing track record of making important contributions to our understanding of the Egfr pathway…”
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Phospho-regulated Drosophila adducin is a determinant of synaptic plasticity in a complex with Dlg and PIP2 at the larval neuromuscular junction by Wang, Simon Ji Hau, Tsai, Amy, Wang, Mannan, Yoo, SooHyun, Kim, Hae-Yoon, Yoo, Byoungjoo, Chui, Vincent, Kisiel, Marta, Stewart, Bryan, Parkhouse, Wade, Harden, Nicholas, Krieger, Charles

“…Adducin is a ubiquitously expressed actin- and spectrin-binding protein involved in cytoskeleton organization, and is regulated through phosphorylation of the…”
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Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles of Rho subfamily proteins in epithelial morphogenesis by Harden, N, Ricos, M, Ong, Y.M, Chia, W, Lim, L

“…The Rho subfamily of Ras-related small GTPases participates in a variety of cellular events including organization of the actin cytoskeleton and signalling by…”
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A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila by Harden, N, Loh, H Y, Chia, W, Lim, L

“…The Rho subfamily of Ras-related small GTP-binding proteins is involved in regulation of the cytoskeleton. The cytoskeletal changes induced by two members of…”
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Studying Nonproliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo by Reed, Bruce, Harden, Nicholas

“…For several decades, genetic analysis in Drosophila has made important contributions to the understanding of signaling by Egfr. Egfr has been well…”
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Structural and Photophysical Properties of Mononuclear and Dinuclear Lanthanide(III) Complexes of Multidentate Podand Ligands Based on Poly(pyrazolyl)borates by Armaroli, Nicola, Accorsi, Gianluca, Barigelletti, Francesco, Couchman, Samantha M, Fleming, James S, Harden, Nicholas C, Jeffery, John C, Mann, Karen L. V, McCleverty, Jon A, Rees, Leigh H, Starling, Sarah R, Ward, Michael D

“…Lanthanide(III) complexes have been prepared with [L1]- [the tetradentate chelating ligand bis{3-(2-pyridyl)pyrazolyl}dihydroborate], [L2]- [the tetradentate…”
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Genetic evidence for antagonism between Pak protein kinase and Rho1 small GTPase signaling in regulation of the actin cytoskeleton during Drosophila oogenesis by Vlachos, Stephanie, Harden, Nicholas

“…During Drosophila oogenesis, basally localized F-actin bundles in the follicle cells covering the egg chamber drive its elongation along the anterior-posterior…”
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ACK Family Tyrosine Kinase Activity Is a Component of Dcdc42 Signaling during Dorsal Closure in Drosophila melanogaster by Sem, Kai Ping, Zahedi, Baharak, Tan, Ivan, Deak, Maria, Lim, Louis, Harden, Nicholas

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Drosophila Cip4/Toca-1 Integrates Membrane Trafficking and Actin Dynamics through WASP and SCAR/WAVE by Fricke, Robert, Gohl, Christina, Dharmalingam, Elavarasi, Grevelhörster, Astrid, Zahedi, Baharak, Harden, Nicholas, Kessels, Michael, Qualmann, Britta, Bogdan, Sven

“…Developmental processes are intimately tied to signaling events that integrate the dynamic reorganization of the actin cytoskeleton and membrane dynamics. The…”
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Hyperpolarized mitochondria accumulate in Drosophila Hipk-overexpressing cells to drive tumor-like growth by Wong, Kenneth Kin Lam, Liao, Jenny Zhe, Shih, Claire R Y, Harden, Nicholas, Verheyen, Esther M

“…Both functional and dysfunctional mitochondria are known to underlie tumor progression. Here, we establish use of the proto-oncogene Homeodomain-interacting…”
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Evolutionary conservation of systemic and reversible amyloid aggregation by Lacroix, Emma, Pereira, Lionel, Yoo, Byoungjoo, Coyle, Krysta M, Chandhok, Sahil, Zapf, Richard, Marijan, Dane, Morin, Ryan D, Vlachos, Stephanie, Harden, Nicholas, Audas, Timothy E

“…In response to environmental stress, human cells have been shown to form reversible amyloid aggregates within the nucleus, termed amyloid bodies (A-bodies)…”
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