Search Results - "Hardaway, John C"
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HITM-SURE: Hepatic immunotherapy for metastases phase Ib anti-CEA CAR-T study utilizing pressure enabled drug delivery
Published in Journal for immunotherapy of cancer (01-08-2020)“…In recent years, cell therapy technologies have resulted in impressive results in hematologic malignancies. Treatment of solid tumors with chimeric antigen…”
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Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity
Published in The Journal of experimental medicine (29-09-2008)“…Primary neonatal T cell responses comprise both T helper (Th) cell subsets, but Th1 cells express high levels of interleukin 13 receptor alpha1 (IL-13R alpha…”
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Regional Delivery of Anti-PD-1 Agent for Colorectal Liver Metastases Improves Therapeutic Index and Anti-Tumor Activity
Published in Vaccines (Basel) (21-07-2021)“…Metastatic liver tumors have presented challenges with the use of checkpoint inhibitors (CPIs), with only limited success. We hypothesize that regional…”
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A taxonomy of perioperative surgical learning: Trending resident skill acquisition
Published in The American journal of surgery (01-02-2017)“…Abstract Background Resident and curriculum evaluation require tracking surgical resident operative performance, yet what and when to measure remains unclear…”
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Regional Infusion of Chimeric Antigen Receptor T Cells to Overcome Barriers for Solid Tumor Immunotherapy
Published in Journal of vascular and interventional radiology (01-07-2018)Get full text
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Decreasing colorectal cancer screening disparities: A culturally tailored patient navigation program for Hispanic patients
Published in Cancer (01-05-2022)“…Background Colorectal cancer (CRC) is the second leading cause of cancer‐related death in Hispanic patients. Screening colonoscopy has been shown to reduce the…”
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Adrenocortical oncocytic neoplasm: A systematic review
Published in Surgery (01-12-2018)“…Adrenocortical oncocytic neoplasms are rare tumors, generally regarded as benign and hormonally nonfunctional. We performed a systematic review to update the…”
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Antigen Receptor T Cells (CAR-T) Effectively Control Tumor Growth in a Colorectal Liver Metastasis Model
Published in The Journal of surgical research (01-04-2022)“…Effective treatment of solid tumors requires multi-modality approaches. In many patients with stage IV liver disease, current treatments are not curative…”
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Perioperative self-reflection among surgical residents
Published in The American journal of surgery (01-09-2017)“…Abstract Background We studied prevalence and predictors of meaningful self-reflection among surgical residents and with prompting/structured interventions,…”
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IL‐13Rα1 is a surface marker for M2 macrophages influencing their differentiation and function
Published in European journal of immunology (01-03-2014)“…In this study, we examined the role IL‐13 receptor alpha 1 (IL‐13Rα1) plays in macrophage differentiation and function. The findings indicate that IL‐13Rα1 is…”
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Comprehensive Multicenter Graduate Surgical Education Initiative Incorporating Entrustable Professional Activities, Continuous Quality Improvement Cycles, and a Web-Based Platform to Enhance Teaching and Learning
Published in Journal of the American College of Surgeons (01-07-2018)“…It is increasingly important for faculty to teach deliberately and provide timely, detailed, and formative feedback on surgical trainee performance. We…”
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Do female surgeons learn or teach differently?
Published in The American journal of surgery (01-02-2017)“…Abstract Background Gender and/or gender-stereotypes might influence surgical education. We hypothesized that female surgeons might focus their learning and…”
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Specific T Regulatory Cells Display Broad Suppressive Functions against Experimental Allergic Encephalomyelitis upon Activation with Cognate Antigen
Published in The Journal of immunology (1950) (01-06-2005)“…To date, very few Ag-based regimens have been defined that could expand T regulatory (Treg) cells to reverse autoimmunity. Additional understanding of Treg…”
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Talking through time: Trends in communication and the evolving patient-physician relationship
Published in Bulletin of the American College of Surgeons (01-08-2016)Get full text
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Bone Marrow-Derived IL-13R alpha 1-Positive Thymic Progenitors Are Restricted to the Myeloid Lineage
Published in The Journal of immunology (1950) (01-04-2012)“…The earliest thymic progenitors (ETPs) were recently shown to give rise to both lymphoid and myeloid cells. Whereas the majority of ETPs are derived from IL-7R…”
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Bone marrow-derived IL-13Rα1-positive thymic progenitors are restricted to the myeloid lineage
Published in The Journal of immunology (1950) (01-04-2012)“…The earliest thymic progenitors (ETPs) were recently shown to give rise to both lymphoid and myeloid cells. Whereas the majority of ETPs are derived from…”
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In Trans T Cell Tolerance Diminishes Autoantibody Responses and Exacerbates Experimental Allergic Encephalomyelitis
Published in The Journal of immunology (1950) (01-02-2008)“…A number of Ag-specific approaches have been developed that ameliorate experimental allergic encephalomyelitis (EAE), an animal model for the human autoimmune…”
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Population Health Initiatives Increase Patient Engagement and Satisfaction with Health Care Services
Published in Journal of the American College of Surgeons (01-10-2018)Get full text
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