Search Results - "Harcus, M"

Screening of High-Risk Families for Pancreatic Cancer by Greenhalf, W, Grocock, C, Harcus, M, Neoptolemos, J

“…Abstract Purpose of Review: To discuss how to recognise and manage high-risk individuals. Recent Findings: Publication of initial results of screening for…”
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Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensisand the evolution of secreted proteins in parasites by Harcus, Yvonne M, Parkinson, John, Fernández, Cecilia, Daub, Jennifer, Selkirk, Murray E, Blaxter, Mark L, Maizels, Rick M

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IL-4R signaling is required to induce IL-10 for the establishment of Th2 dominance by Balic, Adam, Harcus, Yvonne M., Taylor, Matthew D., Brombacher, Frank, Maizels, Rick M.

“…The requirement for IL-4 to promote differentiation of naive CD4+ T cells into Th2 effector cell populations was established by classical in vitro studies…”
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Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses by Holland, Martin J., Harcus, Yvonne M., Riches, Philip L., Maizels, Rick M.

“…Infections with parasitic helminths such as Nippostronglyus brasiliensis induce dominant type 2 responses from antigen‐specific T helper cells. The potency of…”
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Expansion of Foxp3+ Regulatory T Cells in Mice Infected with the Filarial Parasite Brugia malayi by McSorley, Henry J, Harcus, Yvonne M, Murray, Janice, Taylor, Matthew D, Maizels, Rick M

“…Many helminths, including Brugia malayi, are able to establish long-lived infections in immunocompetent hosts. Growing evidence suggests that the immune…”
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The secretome of the filarial parasite, Brugia malayi: Proteomic profile of adult excretory–secretory products by Hewitson, James P., Harcus, Yvonne M., Curwen, Rachel S., Dowle, Adam A., Atmadja, Agnes K., Ashton, Peter D., Wilson, Alan, Maizels, Rick M.

“…The secretome of a parasite in its definitive host can be considered to be its genome in trans, to the extent that secreted products encoded by the parasite…”
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Th2 induction by Nippostrongylus secreted antigens in mice deficient in B cells, eosinophils or MHC Class I-related receptors by Holland, Martin J., Harcus, Yvonne M., Balic, Adam, Maizels, Rick M.

“…The populations of immune system cells necessary for induction of the Th2 response have yet to be fully defined. Among the most consistent natural stimuli for…”
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Immune modulation and modulators in Heligmosomoides polygyrus infection by Maizels, Rick M., Hewitson, James P., Murray, Janice, Harcus, Yvonne M., Dayer, Blaise, Filbey, Kara J., Grainger, John R., McSorley, Henry J., Reynolds, Lisa A., Smith, Katherine A.

“…[Display omitted] ► A comprehensive review of a widely studied model system for helminth infections. ► Synthesises data from many immunology laboratories. ►…”
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Familial pancreatic cancer: a review and latest advances by Grocock, C J, Vitone, L J, Harcus, M J, Neoptolemos, J P, Raraty, M G T, Greenhalf, W

“…Familial Pancreatic Cancer (FPC) is the autosomal dominant inheritance of a genetic predisposition to pancreatic ductal adenocarcinoma, penetrance is assumed…”
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IL-4R signaling is required to induce IL-10 for the establishment of T(h)2 dominance by Balic, Adam, Harcus, Yvonne M, Taylor, Matthew D, Brombacher, Frank, Maizels, Rick M

“…The requirement for IL-4 to promote differentiation of naive CD4(+) T cells into T(h)2 effector cell populations was established by classical in vitro studies…”
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Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis by Keir, P. A., Brown, D. M., Clouter‐Baker, A., Harcus, Y. M., Proudfoot, L.

“…SUMMARY It has been reported that excretory–secretory (ES) material from the parasitic nematode Nippostrongylus brasiliensis has potential modulatory effects…”
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Proteins secreted by the parasitic nematodeNippostrongylus brasiliensis act as adjuvants for Th2 responses by Holland, Martin J., Harcus, Yvonne M., Riches, Philip L., Maizels, Rick M.

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The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families by Grocock, Christopher J, Rebours, Vinciane, Delhaye, Myriam N, Andrén-Sandberg, Ake, Weiss, Frank Ulrich, Mountford, Roger, Harcus, Matthew J, Niemczyck, Edyta, Vitone, Louis J, Dodd, Susanna, Jørgensen, Maiken Thyregod, Ammann, Rudolf W, Schaffalitzky de Muckadell, Ove, Butler, Jane V, Burgess, Phillip, Kerr, Bronwyn, Charnley, Richard, Sutton, Robert, Raraty, Michael G, Devière, Jacques, Whitcomb, David C, Neoptolemos, John P, Lévy, Philippe, Lerch, Markus M, Greenhalf, William

“…To characterise the phenotypes associated with the p.A16V mutation of PRSS1. Clinical and epidemiological data were collected for any family in which a p.A16V…”
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A MATHEMATICAL MODEL TO STRATIFY CANCER RISK IN FAMILIAL PANCREATIC CANCER KINDREDS by Grocock, C., Taktak, A., Eleuteri, A., Tortora, F., Harcus, M., Vitone, L., Sutton, R., Raraty, M., Neoptolemos, J., Greenhalf, W.

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Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites by Harcus, Yvonne M, Parkinson, John, Fernández, Cecilia, Daub, Jennifer, Selkirk, Murray E, Blaxter, Mark L, Maizels, Rick M

“…Parasitism is a highly successful mode of life and one that requires suites of gene adaptations to permit survival within a potentially hostile host. Among…”
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IL-4R signaling is required to induce IL-10 for the establishment of T sub(h)2 dominance by Balic, Adam, Harcus, Yvonne M, Taylor, Matthew D, Brombacher, Frank, Maizels, Rick M

“…The requirement for IL-4 to promote differentiation of naive CD4 super(+) T cells into T sub(h)2 effector cell populations was established by classical in…”
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