Search Results - "Harbin, Sherry"

Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony–forming cells by Prasain, Nutan, Lee, Man Ryul, Vemula, Sasidhar, Meador, Jonathan Luke, Yoshimoto, Momoko, Ferkowicz, Michael J, Fett, Alexa, Gupta, Manav, Rapp, Brian M, Saadatzadeh, Mohammad Reza, Ginsberg, Michael, Elemento, Olivier, Lee, Younghee, Voytik-Harbin, Sherry L, Chung, Hyung Min, Hong, Ki Sung, Reid, Emma, O'Neill, Christina L, Medina, Reinhold J, Stitt, Alan W, Murphy, Michael P, Rafii, Shahin, Broxmeyer, Hal E, Yoder, Mervin C

“…Endothelial cells with properties of cord-blood endothelial colony-forming cells are generated from human pluripotent stem cells. The ability to differentiate…”
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Tissue‐Engineered Implant for Hemilaryngectomy Reconstruction with Recurrent Laryngeal Nerve Injury by Wesson, Troy, Zhang, Lujuan, Morrison, Rachel A., Brookes, Sarah, Calcagno, Haley, Finnegan, Patrick, Voytik‐Harbin, Sherry, Halum, Stacey

“…Objective Laryngeal cancer resections often require excision of portions of the larynx along with sacrifice of the ipsilateral recurrent laryngeal nerve (RLN)…”
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YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility by Mason, Devon E, Collins, Joseph M, Dawahare, James H, Nguyen, Trung Dung, Lin, Yang, Voytik-Harbin, Sherry L, Zorlutuna, Pinar, Yoder, Mervin C, Boerckel, Joel D

“…Cell migration initiates by traction generation through reciprocal actomyosin tension and focal adhesion reinforcement, but continued motility requires…”
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Scaffold‐Forming Collagen and Motor‐Endplate Expressing Muscle Cells for Porcine Laryngoplasty by Shay, Elizabeth O., Morrison, Rachel A., Zhang, Lujuan, Kaefer, Samuel L., Wesson, Troy, Cox, Abigail, Voytik‐Harbin, Sherry L., Halum, Stacey

“…Objective Vocal fold paralysis impairs quality of life, and no curative injectable therapy exists. We evaluated injection of a novel in situ polymerizing…”
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Laryngeal Reconstruction Using Tissue‐Engineered Implants in Pigs: A Pilot Study by Brookes, Sarah, Zhang, Lujuan, Puls, Theodore J., Kincaid, John, Voytik‐Harbin, Sherry, Halum, Stacey

“…Objective/Hypothesis There are currently no treatments available that restore dynamic laryngeal function after hemilaryngectomy. We have shown that dynamic…”
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1464-P: Computational Modeling for Design of Next Generation Microphysiological Systems for Evaluation of ß-Cell Health and Function by VANDERLAAN, EMMA, TEPOLE, ADRIAN BUGANZA, HARBIN, SHERRY L.

“…Dynamic insulin secretion is a key focus of β cell research, with microfluidic devices emerging as a potential means to effectively evaluate this performance…”
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3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT by Puls, T J, Tan, Xiaohong, Whittington, Catherine F, Voytik-Harbin, Sherry L

“…Pancreatic cancer, one of the deadliest cancers, is characterized by high rates of metastasis and intense desmoplasia, both of which are associated with…”
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Motor endplate‐expressing cartilage‐muscle implants for reconstruction of a denervated hemilarynx by Brookes, Sarah, Voytik‐Harbin, Sherry, Zhang, Hongji, Zhang, Lujuan, Halum, Stacey

“…Objective Tissue engineering of the larynx requires a complex, multiple tissue layer design. Additionally, spontaneous reinnervation of the larynx after…”
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Mechanobiological wound model for improved design and evaluation of collagen dermal replacement scaffolds by Sohutskay, David O., Buganza Tepole, Adrian, Voytik-Harbin, Sherry L.

“…[Display omitted] Skin wounds are among the most common and costly medical problems experienced. Despite the myriad of treatment options, such wounds continue…”
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Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition by Herrera-Perez, R Marisol, Voytik-Harbin, Sherry L, Sarkaria, Jann N, Pollok, Karen E, Fishel, Melissa L, Rickus, Jenna L

“…Despite the increasingly recognized importance of the tumor microenvironment (TME) as a regulator of tumor progression, only few in vitro models have been…”
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Mechanisms and Microenvironment Investigation of Cellularized High Density Gradient Collagen Matrices via Densification by Novak, Tyler, Seelbinder, Benjamin, Twitchell, Celina M., van Donkelaar, Corrinus C., Voytik-Harbin, Sherry L., Neu, Corey P.

“…Biological tissues and biomaterials are often defined by unique spatial gradients in physical properties that impart specialized function over hierarchical…”
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Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation by Novak, Tyler, Seelbinder, Benjamin, Twitchell, Celina M., Voytik-Harbin, Sherry L., Neu, Corey P.

“…Current use of decellularized articular cartilage as a regenerative platform suffers from limited implant diffusion characteristics and cellular infiltration…”
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Islet-on-chip: promotion of islet health and function via encapsulation within a polymerizable fibrillar collagen scaffold by Vanderlaan, Emma L, Sexton, Joshua, Evans-Molina, Carmella, Buganza Tepole, Adrian, Voytik-Harbin, Sherry L

“…The protection and interrogation of pancreatic β-cell health and function is a fundamental aspect of diabetes research, including mechanistic studies,…”
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Extracellular Matrix Properties Regulate the Migratory Response of Glioblastoma Stem Cells in Three-Dimensional Culture by Herrera-Perez, Marisol, Voytik-Harbin, Sherry L, Rickus, Jenna L

“…Diffuse infiltration across brain tissue is a hallmark of glioblastoma and the main cause of unsuccessful total resection that leads to tumor reappearance. A…”
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Development of electrochemical Zn2+ sensors for rapid voltammetric detection of glucose-stimulated insulin release from pancreatic β-cells by Vanderlaan, Emma L., Nolan, James K., Sexton, Joshua, Evans-Molina, Carmella, Lee, Hyowon, Voytik-Harbin, Sherry L.

“…Diabetes is a chronic disease characterized by elevated blood glucose levels resulting from absent or ineffective insulin release from pancreatic β-cells…”
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Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening by Puls, T. J., Tan, Xiaohong, Husain, Mahera, Whittington, Catherine F., Fishel, Melissa L., Voytik-Harbin, Sherry L.

“…While much progress has been made in the war on cancer, highly invasive cancers such as pancreatic cancer remain difficult to treat and anti-cancer clinical…”
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Three‐dimensional tissue‐engineered skeletal muscle for laryngeal reconstruction by Brookes, Sarah, Voytik‐Harbin, Sherry, Zhang, Hongji, Halum, Stacey

“…Objective There is an unmet need for tissue‐engineered three‐dimensional (3D) muscle constructs for laryngeal reconstruction. Functional engineered muscle…”
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Early Changes in Porcine Larynges Following Injection of Motor‐Endplate Expressing Muscle Cells for the Treatment of Unilateral Vocal Fold Paralysis by Kaefer, Samuel L., Zhang, Lujuan, Morrison, Rachel A., Brookes, Sarah, Awonusi, Oluwaseyi, Shay, Elizabeth, Hoilett, Orlando S., Anderson, Jennifer L., Goergen, Craig J., Voytik‐Harbin, Sherry, Halum, Stacey

“…Objectives No curative injectable therapy exists for unilateral vocal fold paralysis. Herein, we explore the early implications of muscle‐derived…”
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Multi‐Layered Implant Approach for Hemilaryngectomy Reconstruction in a Porcine Model by Wesson, Troy, Morrison, Rachel A., Zhang, Lujuan, Brookes, Sarah, Kaefer, Sam, Finnegan, Patrick R., Calcagno, Haley, Campiti, Vincent J., Voytik‐Harbin, Sherry, Halum, Stacey

“…Objective Partial laryngectomies result in voice, swallowing, and airway impairment for thousands of patients in the United States each year. Treatment options…”
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Monitoring focal adhesion kinase phosphorylation dynamics in live cells by Damayanti, Nur P, Buno, Kevin, Narayanan, Nagarajan, Voytik Harbin, Sherry L, Deng, Meng, Irudayaraj, Joseph M K

“…Focal adhesion kinase (FAK) is a cytoplasmic non-receptor tyrosine kinase essential for a diverse set of cellular functions. Current methods for monitoring FAK…”
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