Search Results - "Harbeck, Mark"

MicroRNA regulation of integrins by Chen, Weiguo, Harbeck, Mark C, Zhang, Wei, Jacobson, Jeffrey R

“…MicroRNAs (miRNAs) are a family of small RNAs that are ∼20 nucleotides in length and are nontranslated. To date, more than 700 miRNAs have been identified, and…”
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Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation by Peng, Hu, Zhuang, Yugang, Harbeck, Mark C, He, Donghong, Xie, Lishi, Chen, Weiguo

“…Endothelial nitric oxide synthase (eNOS) is responsible for maintaining systemic blood pressure, vascular remodeling and angiogenesis. In addition to producing…”
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Cell physiology of cAMP sensor Epac by Holz, George G., Kang, Guoxin, Harbeck, Mark, Roe, Michael W., Chepurny, Oleg G.

“…Epac is an acronym for the exchange proteins activated directly by cyclic AMP, a family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs) that…”
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Serum- and Glucocorticoid-induced Protein Kinase 1 (SGK1) Is Regulated by Store-operated Ca2+ Entry and Mediates Cytoprotection against Necrotic Cell Death by Brickley, Deanna R., Agyeman, Abena S., Kopp, Richard F., Hall, Ben A., Harbeck, Mark C., Belova, Larissa, Volden, Paul A., Wu, Wei, Roe, Michael W., Conzen, Suzanne D.

“…Serum and glucocorticoid-regulated kinase 1 (SGK1) encodes a phosphatidylinositol 3-kinase-dependent serine/threonine kinase that is rapidly induced in…”
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Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach by Fridlyand, Leonid E, Harbeck, Mark C, Roe, Michael W, Philipson, Louis H

“…In this report we describe a mathematical model for the regulation of cAMP dynamics in pancreatic beta-cells. Incretin hormones such as glucagon-like peptide 1…”
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Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet β-cells by HARBECK, M. C, LOUIE, D. C, HOWLAND, J, WOLF, B. A, ROTHENBERG, P. L

“…The expression of insulin receptor mRNA was examined in rat pancreatic islet cells by single-cell reverse transcriptase (RT)-polymerase chain reaction (PCR)…”
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Novel Mechanism for Nicotinamide Phosphoribosyltransferase Inhibition of TNF-α-mediated Apoptosis in Human Lung Endothelial Cells by Oita, Radu C, Camp, Sara M, Ma, Wenli, Ceco, Ermelinda, Harbeck, Mark, Singleton, Patrick, Messana, Joe, Sun, Xiaoguang, Wang, Ting, Garcia, Joe G N

“…Nicotinamide phosphoribosyltransferase (NAMPT) exists as both intracellular NAMPT and extracellular NAMPT (eNAMPT) proteins. eNAMPT is secreted into the blood…”
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Tyrosine Dephosphorylation and Deactivation of Insulin Receptor Substrate-1 by Protein-tyrosine Phosphatase 1B by Goldstein, Barry J., Bittner-Kowalczyk, Anna, White, Morris F., Harbeck, Mark

“…Regulation of the steady-state tyrosine phosphorylation of the insulin receptor and its postreceptor substrates are essential determinants of insulin signal…”
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Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line[boxs] by Landa, Luis R., Harbeck, Mark, Kaihara, Kelly, Chepurny, Oleg, Kitiphongspattana, Kajorn, Graf, Oliver, Nikolaev, Viacheslav O., Lohse, Martin J., Holz, George G., Roe, Michael W.

“…Ca2+ and cAMP are important second messengers that regulate multiple cellular processes. Although previous studies have suggested direct interactions between…”
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Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein by Goldstein, B J, Bittner-Kowalczyk, A, White, M F, Harbeck, M

“…Regulation of the steady-state tyrosine phosphorylation of the insulin receptor and its postreceptor substrates are essential determinants of insulin signal…”
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A cAMP and Ca2+ coincidence detector in support of Ca2+‐induced Ca2+ release in mouse pancreatic β cells by Kang, Guoxin, Chepurny, Oleg G., Rindler, Michael J., Collis, Leon, Chepurny, Zina, Li, Wen‐hong, Harbeck, Mark, Roe, Michael W., Holz, George G.

“…The blood glucose‐lowering hormone glucagon‐like peptide‐1 (GLP‐1) stimulates cAMP production, promotes Ca2+ influx, and mobilizes an intracellular source of…”
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Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells by Harbeck, Mark C, Chepurny, Oleg, Nikolaev, Viacheslav O, Lohse, Martin J, Holz, George G, Roe, Michael W

“…Understanding the temporal and spatial integration of the Ca2+ and adenosine 3',5'-monophosphate (cAMP) signaling pathways requires concurrent measurements of…”
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Imaging endoplasmic reticulum calcium with a fluorescent biosensor in transgenic mice by Hara, Manami, Bindokas, Vytautas, Lopez, James P, Kaihara, Kelly, Landa, Jr, Luis R, Harbeck, Mark, Roe, Michael W

“…The use of biosynthetic fluorescent sensors is an important new approach for imaging Ca(2+) in cells. Genetically encoded indicators based on green fluorescent…”
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Ca^sup 2+^ Mobilizing Properties of the GLP-1 Receptor: Role of a cAMP and Ca^sup2+^ Coincidence Detector in Support of Ca^sup 2+^-Induced Ca^sup 2+^ Release in Pancreatic Beta-Cells by Kang, Guoxin, Chepurny, Oleg G, Harbeck, Mark, Roe, Michael W, Holz, George G

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Interplay of Ca super(2+) and cAMP Signaling in the Insulin-secreting MIN6 beta -Cell Line by Landa, Luis RJr, Harbeck, Mark, Kaihara, Kelly, Chepurny, Oleg, Kitiphongspattana, Kajorn, Graf, Oliver, Nikolaev, Viacheslav O, Lohse, Martin J, Holz, George G, Roe, Michael W

“…Ca super(2+) and cAMP are important second messengers that regulate multiple cellular processes. Although previous studies have suggested direct interactions…”
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Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line by Luis R. Landa, Jr, Mark Harbeck, Kelly Kaihara, Oleg Chepurny, Kajorn Kitiphongspattana, Oliver Graf, Viacheslav O. Nikolaev, Martin J. Lohse, George G. Holz, Michael W. Roe

“…Ca 2+ and cAMP are important second messengers that regulate multiple cellular processes. Although previous studies have suggested direct interactions between…”
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Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Lines by Landa, Luis R., Harbeck, Mark, Kaihara, Kelly, Chepurny, Oleg, Kitiphongspattana, Kajorn, Graf, Oliver, Nikolaev, Viacheslav O., Lohse, Martin J., Holz, George G., Roe, Michael W.

“…Ca 2+ and cAMP are important second messengers that regulate multiple cellular processes. Although previous studies have suggested direct interactions between…”
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A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic β cells by Guoxin Kang, Oleg G Chepurny, Michael J Rindler, Leon Collis, Zina Chepurny, Wen-hong Li, Mark Harbeck, Michael W Roe, George G Holz

“…The blood glucose-lowering hormone glucagon-like peptide-1 (GLP-1) stimulates cAMP production, promotes Ca 2+ influx, and mobilizes an intracellular source of…”
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A cAMP and Ca 2+ coincidence detector in support of Ca 2+ ‐induced Ca 2+ release in mouse pancreatic β cells by Kang, Guoxin, Chepurny, Oleg G., Rindler, Michael J., Collis, Leon, Chepurny, Zina, Li, Wen‐hong, Harbeck, Mark, Roe, Michael W., Holz, George G.

“…The blood glucose‐lowering hormone glucagon‐like peptide‐1 (GLP‐1) stimulates cAMP production, promotes Ca 2+ influx, and mobilizes an intracellular source of…”
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A cAMP and Ca super(2+) coincidence detector in support of Ca super(2+)-induced Ca super(2+) release in mouse pancreatic beta cells by Kang, Guoxin, Chepurny, Oleg G, Rindler, Michael J, Collis, Leon, Chepurny, Zina, Li, Wen-hong, Harbeck, Mark, Roe, Michael W, Holz, George G

“…The blood glucose-lowering hormone glucagon-like peptide-1 (GLP-1) stimulates cAMP production, promotes Ca super(2+) influx, and mobilizes an intracellular…”
Get full text