Search Results - "Harb, Diala"

S12 Impact of Pancrelipase on Stool Frequency and Consistency in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis or Pancreatic Surgery: Analysis of Randomized Trial Patient-Reported Daily Symptoms by Barkin, Jodie A., Harb, Diala, Yu, Jun, Kort, Jens, Barkin, Jamie S.

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S17 Pancrelipase for the Treatment of Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis: Rationale and Methodology of a Prospective, Observational, Multicenter, Cohort Study by Othman, Mohamed O., Kort, Jens, Lara, Luis, Gonda, Tamas, Kothari, Darshan, Trikudanathan, Guru, Park, Walter, Li, Moming, Harb, Diala

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S44 Analysis of Real World Patient Experience With Pancreatic Enzyme Replacement Therapy (PERT) in the Treatment of Exocrine Pancreatic Insufficiency (EPI) by Barkin, Jodie A., Harb, Diala M., Kort, Jens M., Barkin, Jamie S.

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Assessment of Weight Loss and Gastrointestinal Symptoms Suggestive of Exocrine Pancreatic Dysfunction After Acute Pancreatitis by Phillips, Anna Evans, Ooka, Kohtaro, Pothoulakis, Ioannis, Paragomi, Pedram, Komara, Nicole, Lahooti, Ali, Harb, Diala, Mays, Melanie, Koutroumpakis, Filippos, Stello, Kimberly, Greer, Phil J., Whitcomb, David C., Papachristou, Georgios I.

“…Studies evaluating the natural history of exocrine pancreatic dysfunction (EPD) after acute pancreatitis (AP) are sparse. This study aims to assess incidence…”
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EP 80317, a ligand of the CD36 scavenger receptor, protects apolipoprotein E-deficient mice from developing atherosclerotic lesions by Marleau, Sylvie, Harb, Diala, Bujold, Kim, Avallone, Roberta, Iken, Khadija, Wang, Yanfei, Demers, Annie, Sirois, Martin G, Febbraio, Maria, Silverstein, Roy L, Tremblay, André, Ong, Huy

“…ABSTRACTCD36, a type B scavenger receptor expressed on macrophages, appears to play a major role in fatty streak formation through scavenging oxidatively…”
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Effects of pancreatic enzyme replacement therapy (PERT) on overall survival (OS) in patients (pts) with advanced pancreatic ductal adenocarcinoma (APDAC) and evidence of pancreatic enzyme insufficiency (PEI): A single institution, retrospective, cohort study by Picozzi, Vincent J., Najjar, Anas, Harb, Diala E, Kort, Jens J, Mandelson, Meg T.

“…e16254 Background: Weight loss (WL)/cachexia is common in APDAC and associated with multiple adverse pt outcomes. Current NCCN guidelines recommend PERT in…”
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Effect of pancreatic enzyme replacement therapy (PERT) on body weight in advanced pancreatic cancer (APC) by Picozzi, Vincent J., Najjar, Anas, Harb, Diala E, Kort, Jens J, Mandelson, Meg T.

“…698 Background: Malnutrition/cachexia is common in PC and is associated with multiple adverse patient (pt) outcomes. Current NCCN guidelines recommend PERT in…”
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Real-World Patient Experience With Pancreatic Enzyme Replacement Therapy in the Treatment of Exocrine Pancreatic Insufficiency by Barkin, Jodie A, Harb, Diala, Kort, Jens, Barkin, Jamie S

“…This study aimed to provide patients insights on the management of exocrine pancreatic insufficiency (EPI) with pancreatic enzyme replacement therapy (PERT). A…”
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Combination of Ibrutinib with CD19 Chimeric Antigen Receptor (CAR) T Cells Suggests Greater Contribution to CAR T-Cell Efficacy Than Other Approved BTK Inhibitors in the Preclinical Setting by Plaks, Vicki, Cyril, Vidusha, Riedell, Peter A, Zhao, Qianqian, Hall, Jason, Tan, Joel, Harb, Diala, Davids, Matthew S

“…Background:CD19-directed CAR T-cell therapy has demonstrated remarkable clinical benefits for patients with B-cell malignancies, but impaired CAR T-cell…”
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Impact of pancreatic enzyme replacement therapy (PERT) on clinical outcomes in nonresected pancreatic cancer (PC): Initial results by Picozzi, Vincent J., Hawari, Raneem, Najjar, Anas, Harb, Diala E, Kort, Jens J, Mandelson, Margaret T.

“…Abstract only 400 Background: Current NCCN guidelines recommend PERT use in PC patients (pts) with symptoms of EPI. However, little evidence exists regarding…”
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Introduction and practical approach to exocrine pancreatic insufficiency for the practicing clinician by Othman, Mohamed O, Harb, Diala, Barkin, Jodie A

“…In exocrine pancreatic insufficiency (EPI), the quantity and/or activity of pancreatic digestive enzymes are below the levels required for normal digestion,…”
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556 PANCRELIPASE IMPROVES EXOCRINE PANCREATIC INSUFFICIENCEY (EPI) SYMPTOMS AND HEALTH RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS WITH CHRONIC PANCREATITIS: RESULTS OF THE CISCP STUDY by Ramsey, Mitchell L, Kort, Jens, Othman, Mohamed O., Keihanian, Tara, Lara, Luis F., Gonda, Tamas A., Trikudanathan, Guru, Park, Walter G., Jazrawi, Saad, Brett, Neil R., Li, Moming, Harb, Diala

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Economic Impact of Pancreatic Enzyme Replacement Therapy (PERT) in Pancreatic Cancer Patients Who May Have Exocrine Pancreatic Insufficiency (EPI) Following Pancreatic Surgery: Presidential Poster Award: 98 by Khandelwal, Nikhil, Harb, Diala, Manthena, Shivaji, Reilly, Patrick, Vora, Jamie, Morris-Stiff, Gareth

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Economic Impact of Pancreatic Enzyme Replacement Therapy (PERT) in Pancreatic Cancer Patients Who May Have Exocrine Pancreatic Insufficiency (EPI) Following Pancreatic Surgery by Khandelwal, Nikhil, Harb, Diala, Manthena, Shivaji, Reilly, Patrick, Vora, Jamie, Morris-Stiff, Gareth

“…Introduction: Exocrine pancreatic insufficiency (EPI) is a known consequence of pancreatic head resection. Following surgery, patients with EPI should be…”
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Targeting CD36 With EP 80317 Reduces Remote Inflammatory Response to Hind Limb Ischemia‐Reperfusion in Mice by Elimam, Hanan, Gauvin, Jade, Huynh, David N., Ménard, Liliane, Al‐Hawat, Marie‐Lynn, Harb, Diala, Lubell, William D., Carpentier, André C., Ong, Huy, Marleau, Sylvie

“…Reperfusion of ischemic skeletal muscle triggers oxidative stress and an immediate inflammatory reaction, leading to damage of distant organs such as the…”
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Factors Influencing Prostate‐Specific Antigen Response among Men Treated with Testosterone Therapy for 6 Months by Morgentaler, Abraham, Benesh, Janet A., Denes, Bela S., Kan‐Dobrosky, Natalia, Harb, Diala, Miller, Michael G.

“…Factors influencing prostate‐specific antigen (PSA) changes in men undergoing testosterone (T) therapy have not been well studied. The aim of this study was to…”
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The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation by Harb, Diala, Bujold, Kim, Febbraio, Maria, Sirois, Martin G., Ong, Huy, Marleau, Sylvie

“…Aims CD36 has been shown to associate with non-receptor Src kinases to activate mitogen-activated protein kinases and trigger cytoskeletal remodelling,…”
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A Growth Hormone-Releasing Peptide that Binds Scavenger Receptor CD36 and Ghrelin Receptor Up-Regulates Sterol Transporters and Cholesterol Efflux in Macrophages through a Peroxisome Proliferator-Activated Receptor γ-Dependent Pathway by Avallone, Roberta, Demers, Annie, Rodrigue-Way, Amélie, Bujold, Kim, Harb, Diala, Anghel, Silvia, Wahli, Walter, Marleau, Sylvie, Ong, Huy, Tremblay, André

“…Macrophages play a central role in the pathogenesis of atherosclerosis by accumulating cholesterol through increased uptake of oxidized low-density…”
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EP80317, a selective ligand of the CD36 scavenger receptor, reduces 111In‐labeled macrophages trafficking to atherosclerotic lesions in apoE‐deficient mice by Harb, Diala, Febbraio, Maria, Ong, Huy, Marleau, Sylvie

“…Our recent studies have shown that long‐term (12 weeks) treatment with growth hormone‐releasing peptides (GHRPs), as ligands of the CD36 scavenger receptor,…”
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