Search Results - "Harang, Jenna"

Aerobic Oxidative Amination of Unactivated Alkenes Catalyzed by Palladium by Brice, Jodie L, Harang, Jenna E, Timokhin, Vitaliy I, Anastasi, Natia R, Stahl, Shannon S

“…The first examples of palladium-catalyzed oxidative amination of unactivated alkyl olefins have been identified. To be successful, these reactions must be…”
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From fragments to leads: novel bacterial NAD+-dependent DNA ligase inhibitors by Hale, Michael R., Brassington, Claire, Carcanague, Dan, Embrey, Kevin, Eyermann, Charles J., Giacobbe, Robert A., Gingipalli, Lakshmaiah, Gowravaram, Madhusudhan, Harang, Jenna, Howard, Tina, Ioannidis, Georgine, Jahic, Haris, Kutschke, Amy, Laganas, Valerie A., Loch, James, Miller, Matthew D., Murphy-Benenato, Kerry E., Oguto, Herbert, Otterbein, Ludovic, Patel, Sahil Joe, Shapiro, Adam B., Boriack-Sjodin, P. Ann

“…[Display omitted] Bacterial NAD+-dependent DNA ligase (LigA) is an essential enzyme involved in the repair, replication, and recombination of DNA in all…”
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Negishi cross-coupling enabled synthesis of novel NAD+-dependent DNA ligase inhibitors and SAR development by Murphy-Benenato, Kerry E., Gingipalli, Lakshmaiah, Boriack-Sjodin, P. Ann, Martinez-Botella, Gabriel, Carcanague, Dan, Eyermann, Charles J., Gowravaram, Madhu, Harang, Jenna, Hale, Michael R., Ioannidis, Georgine, Jahic, Harris, Johnstone, Michele, Kutschke, Amy, Laganas, Valerie A., Loch, James T., Miller, Matthew D., Oguto, Herbert, Patel, Sahil Joe

“…[Display omitted] Two novel compounds, pyridopyrimidines (1) and naphthyridines (2) were identified as potent inhibitors of bacterial NAD+-dependent DNA ligase…”
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Discovery of bacterial NAD +-dependent DNA ligase inhibitors: Optimization of antibacterial activity by Stokes, Suzanne S., Huynh, Hoan, Gowravaram, Madhusudhan, Albert, Robert, Cavero-Tomas, Marta, Chen, Brendan, Harang, Jenna, Loch, James T., Lu, Min, Mullen, George B., Zhao, Shannon, Liu, Ce-Feng, Mills, Scott D.

“…Optimization of adenosine analog inhibitors of bacterial NAD +-dependent DNA ligase is discussed. Antibacterial activity against Streptococcus pneumoniae and…”
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Discovery of bacterial NAD super(+-dependent DNA ligase inhibitors: Optimization of antibacterial activity) by Stokes, Suzanne S, Huynh, Hoan, Gowravaram, Madhusudhan, Albert, Robert, Cavero-Tomas, Marta, Chen, Brendan, Harang, Jenna, Loch, James T, Lu, Min, Mullen, George B, Zhao, Shannon, Liu, Ce-Feng, Mills, Scott D

“…Optimization of adenosine analog inhibitors of bacterial NAD super(+-dependent DNA ligase is discussed. Antibacterial activity against Streptococcus pneumoniae…”
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