Search Results - "Haraguchi, Kyoko"

Prognostic impact of TP53 mutation, monosomal karyotype, and prior myeloid disorder in nonremission acute myeloid leukemia at allo-HSCT by Najima, Yuho, Sadato, Daichi, Harada, Yuka, Oboki, Keisuke, Hirama, Chizuko, Toya, Takashi, Doki, Noriko, Haraguchi, Kyoko, Yoshifuji, Kota, Akiyama, Megumi, Inamoto, Kyoko, Igarashi, Aiko, Kobayashi, Takeshi, Kakihana, Kazuhiko, Okuyama, Yoshiki, Sakamaki, Hisashi, Harada, Hironori, Ohashi, Kazuteru

“…Outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in nonremission acute myeloid leukemia (AML) are dismal [2-year overall survival…”
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Impact of gene alterations on clinical outcome in young adults with myelodysplastic syndromes by Konishi, Tatsuya, Sadato, Daichi, Toya, Takashi, Hirama, Chizuko, Kishida, Yuya, Nagata, Akihito, Yamada, Yuta, Shingai, Naoki, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Okuyama, Yoshiki, Harada, Hironori, Ohashi, Kazuteru, Harada, Yuka, Doki, Noriko

“…Young adults with myelodysplastic syndrome (MDS) are rare, and the clinical significance of driver mutations has not yet been analysed. We analysed the gene…”
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Case report: Immune pressure on hematopoietic stem cells can drastically expand glycosylphosphatidylinositol-deficient clones in paroxysmal nocturnal hemoglobinuria by Shingai, Naoki, Mizumaki, Hiroki, Najima, Yuho, Yamada, Yuta, Tran, Dung Cao, Haraguchi, Kyoko, Toya, Takashi, Okuyama, Yoshiki, Doki, Noriko, Nannya, Yasuhito, Ogawa, Seishi, Nakao, Shinji

“…Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disease characterized by intravascular hemolysis, thrombosis, and bone marrow (BM) failure…”
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Early failure is still a poor prognostic factor in patients with relapsed or refractory large B-cell lymphoma in the era of CAR T-cell therapy by Yagi, Yu, Kanemasa, Yusuke, Sasaki, Yuki, Goto, Sotaro, Yamamura, Yasuhiko, Masuda, Yusuke, Fujita, Kumiko, Ishimine, Kento, Hayashi, Yudai, Mino, Mano, Ohigashi, An, Morita, Yuka, Tamura, Taichi, Nakamura, Shohei, Okuya, Toshihiro, Matsuda, Shinichiro, Shimizuguchi, Takuya, Shingai, Naoki, Toya, Takashi, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Doki, Noriko, Okuyama, Yoshiki, Shimoyama, Tatsu

“…Patients with refractory or relapsed (R/R) large B-cell lymphoma (LBCL) refractory to first-line chemotherapy or with early relapse have poor outcomes. While…”
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Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia by Nakahara, Fumio, Sakata-Yanagimoto, Mamiko, Komeno, Yukiko, Kato, Naoko, Uchida, Tomoyuki, Haraguchi, Kyoko, Kumano, Keiki, Harada, Yuka, Harada, Hironori, Kitaura, Jiro, Ogawa, Seishi, Kurokawa, Mineo, Kitamura, Toshio, Chiba, Shigeru

“…Hairy enhancer of split 1 (Hes1) is a basic helix-loop-helix transcriptional repressor that affects differentiation and often helps maintain cells in an…”
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Clinical outcomes in transplant‐eligible patients with relapsed or refractory diffuse large B‐cell lymphoma after second‐line salvage chemotherapy: A retrospective study by Yagi, Yu, Kanemasa, Yusuke, Sasaki, Yuki, Sei, Mina, Matsuo, Takuma, Ishimine, Kento, Hayashi, Yudai, Mino, Mano, Ohigashi, An, Morita, Yuka, Tamura, Taichi, Nakamura, Shohei, Okuya, Toshihiro, Shimizuguchi, Takuya, Shingai, Naoki, Toya, Takashi, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Doki, Noriko, Okuyama, Yoshiki, Shimoyama, Tatsu

“…Abstract Objective The prognosis of patients with relapsed or refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) is poor. Although patients who fail…”
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Clinical impact of hematogones on outcomes of allogeneic hematopoietic stem cell transplantation by Doki, Noriko, Haraguchi, Kyoko, Hagino, Takeshi, Igarashi, Aiko, Najima, Yuho, Kobayashi, Takeshi, Kakihana, Kazuhiko, Okuyama, Yoshiki, Sakamaki, Hisashi, Ohashi, Kazuteru

“…Increased levels of normal B cell precursors, termed hematogones (HGs), are observed in regenerating bone marrow after chemotherapy or hematopoietic stem cell…”
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Mutation profiles of diffuse large B‐cell lymphoma transformation of splenic B‐cell lymphoma/leukemia, unclassifiable on whole‐exome sequencing by Kurosawa, Shuhei, Toya, Takashi, Sadato, Daichi, Hishima, Tsunekazu, Hirama, Chizuko, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Okuyama, Yoshiki, Oboki, Keisuke, Harada, Hironori, Sakamaki, Hisashi, Ohashi, Kazuteru, Harada, Yuka, Doki, Noriko

“…A 58‐year‐old male was diagnosed with splenic B‐cell lymphoma/leukemia, unclassifiable (SPLL‐U). The lymphoma transformed into diffuse large B‐cell lymphoma…”
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Donor-derived gene mutations in sex chromosome loss after stem cell transplantation by Adachi, Hiroto, Sadato, Daichi, Toya, Takashi, Hirama, Chizuko, Haraguchi, Kyoko, Mukae, Junichi, Shingai, Naoki, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Okuyama, Yoshiki, Oboki, Keisuke, Harada, Hironori, Sakamaki, Hisashi, Ohashi, Kazuteru, Harada, Yuka, Doki, Noriko

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Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15 by Haraguchi, Kyoko, Suzuki, Takahiro, Koyama, Noriko, Kumano, Keiki, Nakahara, Fumio, Matsumoto, Akihiko, Yokoyama, Yasuhisa, Sakata-Yanagimoto, Mamiko, Masuda, Shigeo, Takahashi, Tsuyoshi, Kamijo, Aki, Takahashi, Koki, Takanashi, Minoko, Okuyama, Yoshiki, Yasutomo, Koji, Sakano, Seiji, Yagita, Hideo, Kurokawa, Mineo, Ogawa, Seishi, Chiba, Shigeru

“…The development of NK cells from hematopoietic stem cells is thought to be dependent on IL-15. In this study, we demonstrate that stimulation of human cord…”
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Relationship between bone marrow cellularity and apparent diffusion coefficient by Nonomura, Yoshie, Yasumoto, Mayumi, Yoshimura, Ryoichi, Haraguchi, Kyoko, Ito, Sukeyuki, Akashi, Takumi, Ohashi, Isamu

“…This study was performed to determine if there is a relationship between apparent diffusion coefficient (ADC) and cellularity of bone marrow of the posterior…”
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Clinical impact of CD25 expression on outcomes of allogeneic hematopoietic stem cell transplant for cytogenetically intermediate-risk acute myeloid leukemia by Ikegawa, Shuntaro, Doki, Noriko, Yamamoto, Keita, Shingai, Naoki, Takahashi, Yukie, Aoki, Jun, Yoshioka, Kosuke, Narukawa, Kensuke, Ishida, Shinya, Igarashi, Aiko, Oshikawa, Gaku, Kobayashi, Takeshi, Kakihana, Kazuhiko, Sakamaki, Hisashi, Haraguchi, Kyoko, Okuyama, Yoshiki, Ohashi, Kazuteru

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Kidney transplantation for end-stage renal disease after third allogeneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia by Nishijima, Akihiko, Shingai, Naoki, Ohta, Akihito, Suda, Kiyoko, Omoto, Kazuya, Ishida, Shinya, Yoshioka, Kosuke, Kurosawa, Shuhei, Hino, Yutaro, Senoo, Yasushi, Igarashi, Aiko, Oshikawa, Gaku, Hamamura, Atsushi, Toya, Takashi, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Okuyama, Yoshiki, Ohashi, Kazuteru, Doki, Noriko

“…An 18-year-old man underwent allogenic bone marrow transplantation (BMT) for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL). Ph+ALL…”
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Polatuzumab vedotin, bendamustine, and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma, including the outcome as a bridging treatment to CAR-T cell therapy or allogeneic hematopoietic stem cell transplant by Morita, Yuka, Yagi, Yu, Kanemasa, Yusuke, Sasaki, Yuki, Ishimine, Kento, Hayashi, Yudai, Mino, Mano, Ohigashi, An, Tamura, Taichi, Nakamura, Shohei, Okuya, Toshihiro, Shimizuguchi, Takuya, Shingai, Naoki, Toya, Takashi, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Doki, Noriko, Okuyama, Yoshiki, Ohashi, Kazuteru, Shimoyama, Tatsu

“…Pola-BR (polatuzumab vedotin, bendamustine, and rituximab) therapy received approval for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) in Japan…”
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Immunotherapy against metastatic renal cell carcinoma with mature dendritic cells by Matsumoto, Akihiko, Haraguchi, Kyoko, Takahashi, Tsuyoshi, Azuma, Takeshi, Kanda, Yoshinobu, Tomita, Kyoichi, Kurokawa, Mineo, Ogawa, Seishi, Takahashi, Koki, Chiba, Shigeru, Kitamura, Tadaichi

“…Objective:  We performed a clinical trial of immunotherapy using autologous mature dendritic cells (DC) pulsed with autologous tumor lysate, for patients with…”
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Prior harvesting and cryopreservation of peripheral blood stem cells from related donors: current situations in Japan by Kobayashi, Takeshi, Ohashi, Kazuteru, Haraguchi, Kyoko, Okuyama, Yoshiki, Hino, Masayuki, Tanaka, Junji, Ueda, Yasunori, Nishida, Tetsuya, Atsuta, Yoshiko, Takanashi, Minoko, Iida, Minako, Muroi, Kazuo, Yabe, Hiromasa, Miyamura, Koichi

“…Although peripheral blood stem cell (PBSC) transplantations in an unrelated transplant setting have been performed since 2010, prior harvesting and…”
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Recurrent DDX41 mutation in very late relapse after allogeneic stem cell transplantation by Kambara, Yasuhiro, Sadato, Daichi, Toya, Takashi, Honda, Akira, Kato, Seiko, Hirama, Chizuko, Haraguchi, Kyoko, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Okuyama, Yoshiki, Harada, Hironori, Takahashi, Satoshi, Kurokawa, Mineo, Harada, Yuka, Doki, Noriko

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Azacitidine and gemtuzumab ozogamicin as post-transplant maintenance therapy for high-risk hematologic malignancies by Kaito, Satoshi, Najima, Yuho, Sadato, Daichi, Hirama, Chizuko, Kishida, Yuya, Nagata, Akihito, Konishi, Tatsuya, Yamada, Yuta, Kurosawa, Shuhei, Yoshifuji, Kota, Shirane, Shuichi, Shingai, Naoki, Toya, Takashi, Shimizu, Hiroaki, Haraguchi, Kyoko, Kobayashi, Takeshi, Harada, Hironori, Okuyama, Yoshiki, Harada, Yuka, Doki, Noriko

“…Disease recurrence remains the principal cause of treatment failure after allogeneic hematopoietic stem cell transplantation. Post-transplant maintenance…”
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Prognostic Impacts of Additional Cytogenetic Abnormalities Acquired at the First Relapse in Adult Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplant in Second Complete Remission by Shimizu, Hiroaki, Mukae, Junichi, Shingai, Naoki, Toya, Takashi, Najima, Yuho, Kobayashi, Takeshi, Hatsumi, Nahoko, Takada, Satoru, Handa, Hiroshi, Haraguchi, Kyoko, Okuyama, Yoshiki, Sakamaki, Hisashi, Ohashi, Kazuteru, Doki, Noriko

“…Background: Additional cytogenetic abnormalities (ACA), the most frequent form of cytogenetic changes, are considered as a result of genetic instability and…”
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Venetoclax-Based Therapy before Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia by Kato, Chika, Najima, Yuho, Sadato, Daichi, Hirama, Chizuko, Kato, Kana, Kondo, Kaori, Sadaga, Yasutaka, Sakai, Satoshi, Kambara, Yasuhiro, Nabe, Yoshimi, Teshima, Ko, Asano, Kazuya, Kurihara, Kazuya, Jinguji, Atsushi, Shimabukuro, Masashi, Ouchi, Fumihiko, Inai, Kazuki, Koi, Satoshi, Shingai, Naoki, Toya, Takashi, Shimizu, Hiroaki, Haraguchi, Kyoko, Kobayashi, Takeshi, Harada, Hironori, Okuyama, Yoshiki, Harada, Yuka, Doki, Noriko

“…Introduction The BCL-2 inhibitor venetoclax (VEN) is effective in older patients with untreated acute myeloid leukemia (AML). Few reports exist on the use of…”
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