Search Results - "Harada, Toshiko"

Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple Negative Breast Cancer: Optimizing the Conjugate-Light Regimen by Nagaya, Tadanobu, Sato, Kazuhide, Harada, Toshiko, Nakamura, Yuko, Choyke, Peter L, Kobayashi, Hisataka

“…Triple-negative breast cancer (TNBC) is considered one of the most aggressive subtypes of breast cancer. Near infrared photoimmunotherapy (NIR-PIT) is a cancer…”
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Photoimmunotherapy targeting prostate-specific membrane antigen: are antibody fragments as effective as antibodies? by Watanabe, Rira, Hanaoka, Hirofumi, Sato, Kazuhide, Nagaya, Tadanobu, Harada, Toshiko, Mitsunaga, Makoto, Kim, Insook, Paik, Chang H, Wu, Anna M, Choyke, Peter L, Kobayashi, Hisataka

“…Photoimmunotherapy is a highly cell-selective cancer therapy based on an armed antibody conjugate with a phthalocyanine-based photosensitizer, IR700…”
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Near infrared photoimmunotherapy of B-cell lymphoma by Nagaya, Tadanobu, Nakamura, Yuko, Sato, Kazuhide, Harada, Toshiko, Choyke, Peter L., Kobayashi, Hisataka

“…Near infrared photoimmunotherapy (NIR-PIT) is a new, highly-selective cancer theranostics that employs an antibody-photo absorber conjugate (APC). NIR-PIT has…”
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Improved micro-distribution of antibody-photon absorber conjugates after initial near infrared photoimmunotherapy (NIR-PIT) by Nagaya, Tadanobu, Nakamura, Yuko, Sato, Kazuhide, Harada, Toshiko, Choyke, Peter L., Kobayashi, Hisataka

“…Near infrared photoimmunotherapy (NIR-PIT), a targeted cancer therapy which uses an antibody-photo absorber conjugate (APC) and near infrared light exposure,…”
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Glypican‑3 Targeted Human Heavy Chain Antibody as a Drug Carrier for Hepatocellular Carcinoma Therapy by Hanaoka, Hirofumi, Nagaya, Tadanobu, Sato, Kazuhide, Nakamura, Yuko, Watanabe, Rira, Harada, Toshiko, Gao, Wei, Feng, Mingqian, Phung, Yen, Kim, Insook, Paik, Chang H, Choyke, Peter L, Ho, Mitchell, Kobayashi, Hisataka

“…Glypican-3 (GPC3) represents an attractive target for hepatocellular carcinoma (HCC) therapy because it is highly expressed in HCC but not in adult normal…”
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Photoimmunotherapy: Comparative effectiveness of two monoclonal antibodies targeting the epidermal growth factor receptor by Sato, Kazuhide, Watanabe, Rira, Hanaoka, Hirofumi, Harada, Toshiko, Nakajima, Takahito, Kim, Insook, Paik, Chang H., Choyke, Peter L., Kobayashi, Hisataka

“…Photoimmunotherapy (PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with the toxicity induced by…”
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The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity by Nakajima, Takahito, Sato, Kazuhide, Hanaoka, Hirofumi, Watanabe, Rira, Harada, Toshiko, Choyke, Peter L, Kobayashi, Hisataka

“…Photoimmunotherapy (PIT) is a highly cell-selective cancer therapy, which employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700)…”
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Near infrared photoimmunotherapy prevents lung cancer metastases in a murine model by Sato, Kazuhide, Nagaya, Tadanobu, Nakamura, Yuko, Harada, Toshiko, Choyke, Peter L, Kobayashi, Hisataka

“…Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the specificity of intravenously injected antibodies with the acute toxicity…”
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Emergency gastrointestinal surgery in patients undergoing antithrombotic therapy in a single general hospital: a propensity score-matched analysis by Abe, Shinya, Ami, Katsunori, Katsuno, Akira, Tamura, Noriyasu, Harada, Toshiko, Hamasaki, Shunsuke, Kitagawa, Yusuke, Machida, Taku, Umetani, Naoyuki

“…Background This study aimed to review and evaluate the surgical outcomes, particularly intraoperative severe blood loss and postoperative blood complications,…”
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Impact of C4′‑O‑Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates by Sato, Kazuhide, Nagaya, Tadanobu, Nakamura, Yuko, Harada, Toshiko, Nani, Roger R, Shaum, James B, Gorka, Alexander P, Kim, Insook, Paik, Chang H, Choyke, Peter L, Schnermann, Martin J, Kobayashi, Hisataka

“…Near-infrared (NIR) fluorophores have several advantages over visible-light fluorophores, including superior tissue penetration and lower autofluorescence. We…”
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MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy by Nakamura, Yuko, Bernardo, Marcelino, Nagaya, Tadanobu, Sato, Kazuhide, Harada, Toshiko, Choyke, Peter L, Kobayashi, Hisataka

“…Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with the toxicity induced…”
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Minibody-Indocyanine Green Based Activatable Optical Imaging Probes: The Role of Short Polyethylene Glycol Linkers by Watanabe, Rira, Sato, Kazuhide, Hanaoka, Hirofumi, Harada, Toshiko, Nakajima, Takahito, Kim, Insook, Paik, Chang H, Wu, Anna M, Choyke, Peter L, Kobayashi, Hisataka

“…Minibodies show rapider blood clearance than IgGs due to smaller size that improves target-to-background ratio (TBR) in in vivo imaging. Additionally, the…”
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A Case of Rectal Cancer with Hemorrhagic Shock with Bleeding Controlled via Stent Placement That Underwent Radical Resection after Preoperative CRT by Ami, Katsunori, Suyama, Yuto, Nakanishi, Akihito, Hakozaki, Tomoki, Harada, Toshiko, Monma, Satoko, Tamura, Noriyasu, Ooide, Kei, Machinami, Rikuo, Umetani, Naoaki

“…Colorectal stents are used mainly for the palliative treatment of colorectal obstruction or preoperative re-obstruction. However, the hemostatic effect of…”
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Fluorescence‐lifetime molecular imaging can detect invisible peritoneal ovarian tumors in bloody ascites by Nakajima, Takahito, Sano, Kohei, Sato, Kazuhide, Watanabe, Rira, Harada, Toshiko, Hanaoka, Hirofumi, Choyke, Peter L., Kobayashi, Hisataka

“…Blood contamination, such as bloody ascites or hemorrhages during surgery, is a potential hazard for clinical application of fluorescence imaging. In order to…”
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Two Cases of Pneumocystis Jirovecii Pneumonia during Chemotherapy for Gastrointestinal Cancer by Kitagawa, Yusuke, Takase, Fumika, Katsuno, Akira, Tamura, Noriyasu, Harada, Toshiko, Hamasaki, Shunsuke, Machida, Taku, Nakanishi, Akihito, Ami, Katsunori, Umetani, Naoyuki

“…In recent years, there has been an increasing incidence of Pneumocystis jirovecci pneumonia(PCP)in immunosuppressed non-HIV patients. However, only a few…”
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Two Cases of Peritoneal Dissemination of Gastric Cancer Treated with CART Followed by Chemotherapy by Kitagawa, Yusuke, Katsuno, Akira, Tamura, Noriyasu, Harada, Toshiko, Abe, Shinya, Hamasaki, Shunsuke, Machida, Taku, Nakanishi, Akihito, Ami, Katsunori, Umetani, Naoyuki

“…Cell-free and concentrated ascites reinfusion therapy(CART)is useful for relief of the symptoms caused by malignant ascites. We experienced 2 cases of…”
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Two cases of pressure ulcer healing after liver transplantation in cirrhosis patients by INUI, Shigeki, HARADA, Toshiko, NAKAJIMA, Takeshi, ITAMI, Satoshi

“…ABSTRACT We report two cases of pressure ulcers in liver cirrhosis patients. In case 1, a 64‐year‐old Japanese woman had suffered from liver cirrhosis caused…”
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Successful Intervention for Pressure Ulcer by Nutrition Support Team: A Case Report by Inui, Shigeki, Konishi, Yuko, Yasui, Yoko, Harada, Toshiko, Itami, Satoshi

“…A 23-year-old woman with heart failure developed pressure ulcer on her sacral area due to a long-term bed rest and impaired hemodynamics. The ulcer improved…”
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Near infrared photoimmunotherapy with avelumab, an anti-programmed death-ligand 1 (PD-L1) antibody by Nagaya, Tadanobu, Nakamura, Yuko, Sato, Kazuhide, Harada, Toshiko, Choyke, Peter L, Hodge, James W, Schlom, Jeffrey, Kobayashi, Hisataka

“…Near Infrared-Photoimmunotherapy (NIR-PIT) is a highly selective tumor treatment that employs an antibody-photo-absorber conjugate (APC). Programmed cell death…”
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Activatable Organic Near-Infrared Fluorescent Probes Based on a Bacteriochlorin Platform: Synthesis and Multicolor in Vivo Imaging with a Single Excitation by Harada, Toshiko, Sano, Kohei, Sato, Kazuhide, Watanabe, Rira, Yu, Zhanqian, Hanaoka, Hirofumi, Nakajima, Takahito, Choyke, Peter L, Ptaszek, Marcin, Kobayashi, Hisataka

“…Near infrared (NIR) fluorescent probes are ideal for in vivo imaging because they offer deeper tissue penetration and lower background autofluorescence…”
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