Search Results - "Hapgood, Karen P."

A quantitative framework for the formation of liquid marbles and hollow granules from hydrophobic powders by Eshtiaghi, Nicky, Hapgood, Karen P.

“…Liquid marbles are micro reservoirs of fluid surrounded by a powder shell. Their unique properties show promise for high-value technological applications in…”
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Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders by Qu, Li, Zhou, Qi (Tony), Denman, John A., Stewart, Peter J., Hapgood, Karen P., Morton, David A.V.

“…[Display omitted] This study investigates the effects of a variety of coating materials on the flowability and dissolution of dry-coated cohesive ibuprofen…”
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Bulk Flow Optimisation of Amorphous Solid Dispersion Excipient Powders through Surface Modification by Suhaidi, Danni, Dong, Yao-Da, Wynne, Paul, Hapgood, Karen P, Morton, David A V

“…Particulate amorphous solid dispersions (ASDs) have been recognised for their potential to enhance the performance of various solid dose forms, especially oral…”
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Nucleation regime map for liquid bound granules by Hapgood, Karen P., Litster, James D., Smith, Rachel

“…Nucleation is the first step in granulation where the powder and liquid first contact. Two types of nucleation in wet granulation processes are proposed. Drop…”
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An analysis of the thermodynamic conditions for solid powder particles spreading over liquid surface by Nguyen, Thanh H., Eshtiaghi, Nicky, Hapgood, Karen P., Shen, Wei

“…The spreading of solid powder over a liquid surface is a prevalent phenomenon encountered in many industrial processes such as food and pharmaceutical…”
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Producing hollow granules from hydrophobic powders in high-shear mixer granulators by Eshtiaghi, Nicky, Arhatari, Benedicta, Hapgood, Karen P.

“…The formation of hollow granules from hydrophobic powders in a high-shear mixer granulator has been investigated by changing the binder/powder mass ratio and…”
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3D printing with particles as feedstock materials by Zhang, Jun, Amini, Negin, Morton, David A.V., Hapgood, Karen P

“…[Display omitted] •This is the first review of 3D printing techniques from a powder and particulate perspective.•The particulate feedstock materials are…”
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The academic jungle: ecosystem modelling reveals why women are driven out of research by O'Brien, Katherine R., Hapgood, Karen P.

“…The number of women studying science and engineering at undergraduate and postgraduate levels has increased markedly in recent decades. However females have…”
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Granulation of hydrophobic powders by Hapgood, Karen P., Khanmohammadi, Batool

“…Granulation of hydrophobic powders is frequently required in the pharmaceutical industry. The structural complexity of new drug molecules mean that is…”
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An investigation on the dissolution qualities of foam granulated products by Mutch, George A., Hapgood, Karen P., Shen, Rui, Selomulya, Cordelia

“…The worldwide home care industry makes widespread use of granulated laundry powders which must be highly soluble and dissolve rapidly to induce an effective…”
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Understanding and preventing agglomeration in a filter drying process by Lim, Hong Lee, Hapgood, Karen P., Haig, Brian

“…The occurrence of severe agglomeration during a filter drying process is a challenging issue in the pharmaceutical industry and has yet to be fully understood…”
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Single-step Coprocessing of Cohesive Powder via Mechanical Dry Coating for Direct Tablet Compression by Qu, Li, Stewart, Peter J, Hapgood, Karen P, Lakio, Satu, Morton, David A V, Zhou, Qi Tony

“…This study aims at testing the feasibility of a single-step coating process to produce a powder formulation of active and inactive ingredients for direct…”
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Highlighting DEM’s Potential to Gauge Mechanistic Attributes of MUPS Tablet and Capsule Formulations by Shekhar, Shishir, Amini, Negin, Morton, David A. V., Hapgood, Karen P., Russell, Alexander

“…Simulation of pharmaceutical unit operations by the discrete element method (DEM) has elevated our understanding of the impact of single-particle interactions…”
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A method to predict nuclei size distributions for use in models of wet granulation by Hapgood, Karen P., Tan, Melvin X.L., Chow, Darren W.Y.

“…Models of granulation and agglomeration are becoming more sophisticated and accurate, but nucleation is poorly understood. Models of granulation processes…”
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Liquid marble formation: Spreading coefficients or kinetic energy? by Eshtiaghi, Nicky, Liu, Jacques S., Shen, Wei, Hapgood, Karen P.

“…A liquid marble is a network of self-assembled hydrophobic powder around a droplet. The mechanism and driving force leading to the formation of liquid marbles…”
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Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate by Qu, Li, Zhou, Qi (Tony), Gengenbach, Thomas, Denman, John A., Stewart, Peter J., Hapgood, Karen P., Gamlen, Michael, Morton, David A. V.

“…Abstract Intensive dry powder coating (mechanofusion) with tablet lubricants has previously been shown to give substantial powder flow improvement. This study…”
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Distribution nucleation: Quantifying liquid distribution on the particle surface using the dimensionless particle coating number by Kariuki, Waithira I.J., Freireich, Ben, Smith, Rachel M., Rhodes, Martin, Hapgood, Karen P.

“…Control of nucleation in wet granulation often determines the size and structure of the final granules. After a decade of research, our knowledge of “immersion…”
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Formation of hollow granules from liquid marbles: Small scale experiments by Eshtiaghi, Nicky, Liu, Jacques J.S., Hapgood, Karen P.

“…Research into formation of hollow granules from liquid marbles is an emerging field in hydrophobic granulation. A liquid marble is formed by a network of…”
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Drop Penetration into Porous Powder Beds by Hapgood, Karen P., Litster, James D., Biggs, Simon R., Howes, Tony

“…The kinetics of drop penetration were studied by filming single drops of several different fluids (water, PEG200, PEG600, and HPC solutions) as they penetrated…”
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Application of the unified compaction curve to link wet granulation and tablet compaction behaviour by Nguyen, Thanh H., Morton, David A.V., Hapgood, Karen P.

“…Tablets make up approximately one third of all drug dosage forms which makes tablet manufacture a common process in the pharmaceutical industry. The unified…”
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