Search Results - "Hapfelmeier, Siegfried"

Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions by Romoli, Ottavia, Schönbeck, Johan Claes, Hapfelmeier, Siegfried, Gendrin, Mathilde

“…The mosquito microbiota impacts the physiology of its host and is essential for normal larval development, thereby influencing transmission of vector-borne…”
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Outrunning Salmonella – the role of endogenous Enterobacteriaceae in variable colonization resistance by Hapfelmeier, Siegfried

“…The mammalian gut microbiota confers colonization resistance against pathogenic bacteria. Specific pathogen-free C57BL/6 mice from different vendors are…”
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The maternal microbiota drives early postnatal innate immune development by de Agüero, Mercedes Gomez, Ganal-Vonarburg, Stephanie C., Fuhrer, Tobias, Rupp, Sandra, Uchimura, Yasuhiro, Li, Hai, Steinert, Anna, Heikenwalder, Mathias, Hapfelmeier, Siegfried, Sauer, Uwe, McCoy, Kathy D., Macpherson, Andrew J.

“…Postnatal colonization of the body with microbes is assumed to be the main stimulus to postnatal immune development. By transiently colonizing pregnant female…”
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Gut Microbiota Orchestrates Energy Homeostasis during Cold by Chevalier, Claire, Stojanović, Ozren, Colin, Didier J., Suarez-Zamorano, Nicolas, Tarallo, Valentina, Veyrat-Durebex, Christelle, Rigo, Dorothée, Fabbiano, Salvatore, Stevanović, Ana, Hagemann, Stefanie, Montet, Xavier, Seimbille, Yann, Zamboni, Nicola, Hapfelmeier, Siegfried, Trajkovski, Mirko

“…Microbial functions in the host physiology are a result of the microbiota-host co-evolution. We show that cold exposure leads to marked shift of the microbiota…”
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Microbiota depletion promotes browning of white adipose tissue and reduces obesity by Suárez-Zamorano, Nicolas, Fabbiano, Salvatore, Chevalier, Claire, Stojanović, Ozren, Colin, Didier J, Stevanović, Ana, Veyrat-Durebex, Christelle, Tarallo, Valentina, Rigo, Dorothée, Germain, Stéphane, Ilievska, Miroslava, Montet, Xavier, Seimbille, Yann, Hapfelmeier, Siegfried, Trajkovski, Mirko

“…Browning of white adipose tissue is induced by depletion of the microbiota, improving metabolic disease and reducing obesity. Brown adipose tissue (BAT)…”
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Biogeography of microbial bile acid transformations along the murine gut by Marion, Solenne, Desharnais, Lyne, Studer, Nicolas, Dong, Yuan, Notter, Matheus D., Poudel, Suresh, Menin, Laure, Janowczyk, Andrew, Hettich, Robert L., Hapfelmeier, Siegfried, Bernier-Latmani, Rizlan

“…Bile acids, which are synthesized from cholesterol by the liver, are chemically transformed along the intestinal tract by the gut microbiota, and the products…”
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Robust microbe immune recognition in the intestinal mucosa by Schären, Olivier P., Hapfelmeier, Siegfried

“…The mammalian mucosal immune system acts as a multitasking mediator between bodily function and a vast diversity of microbial colonists. Depending on…”
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Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response by Uchimura, Yasuhiro, Fuhrer, Tobias, Li, Hai, Lawson, Melissa A., Zimmermann, Michael, Yilmaz, Bahtiyar, Zindel, Joel, Ronchi, Francesca, Sorribas, Marcel, Hapfelmeier, Siegfried, Ganal-Vonarburg, Stephanie C., Gomez de Agüero, Mercedes, McCoy, Kathy D., Sauer, Uwe, Macpherson, Andrew J.

“…Although the mammalian microbiota is well contained within the intestine, it profoundly shapes development and metabolism of almost every host organ. We…”
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The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota by Balmer, Maria L, Slack, Emma, de Gottardi, Andrea, Lawson, Melissa A E, Hapfelmeier, Siegfried, Miele, Luca, Grieco, Antonio, Van Vlierberghe, Hans, Fahrner, René, Patuto, Nicola, Bernsmeier, Christine, Ronchi, Francesca, Wyss, Madeleine, Stroka, Deborah, Dickgreber, Nina, Heim, Markus H, McCoy, Kathy D, Macpherson, Andrew J

“…A prerequisite for establishment of mutualism between the host and the microbial community that inhabits the large intestine is the stringent mucosal…”
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In vitro and in vivo characterization of Clostridium scindens bile acid transformations by Marion, Solenne, Studer, Nicolas, Desharnais, Lyne, Menin, Laure, Escrig, Stéphane, Meibom, Anders, Hapfelmeier, Siegfried, Bernier-Latmani, Rizlan

“…The human gut hosts trillions of microorganisms that exert a profound influence on human biology. Gut bacteria communicate with their host by secreting small…”
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Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling by Balmer, Maria L, Schürch, Christian M, Saito, Yasuyuki, Geuking, Markus B, Li, Hai, Cuenca, Miguelangel, Kovtonyuk, Larisa V, McCoy, Kathy D, Hapfelmeier, Siegfried, Ochsenbein, Adrian F, Manz, Markus G, Slack, Emma, Macpherson, Andrew J

“…Neutropenia is probably the strongest known predisposition to infection with otherwise harmless environmental or microbiota-derived species. Because initial…”
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Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses by Hapfelmeier, Siegfried, Lawson, Melissa A.E, Slack, Emma, Kirundi, Jorum K, Stoel, Maaike, Heikenwalder, Mathias, Cahenzli, Julia, Velykoredko, Yuliya, Balmer, Maria L, Endt, Kathrin, Geuking, Markus B, Curtiss, Roy 3rd, McCoy, Kathy D, Macpherson, Andrew J

“…The lower intestine of adult mammals is densely colonized with nonpathogenic (commensal) microbes. Gut bacteria induce protective immune responses, which…”
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Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid by Vico-Oton, Eduard, Volet, Colin, Jacquemin, Nicolas, Dong, Yuan, Hapfelmeier, Siegfried, Meibom, Karin Lederballe, Bernier-Latmani, Rizlan

“…Bile acids (BAs) are steroid-derived molecules with important roles in digestion, the maintenance of host metabolism, and immunomodulation. Primary BAs are…”
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Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism by Slack, Emma, Hapfelmeier, Siegfried, Stecher, Bärbel, Velykoredko, Yuliya, Stoel, Maaike, Lawson, Melissa A.E, Geuking, Markus B, Beutler, Bruce, Tedder, Thomas F, Hardt, Wolf-Dietrich, Bercik, Premysl, Verdu, Elena F, McCoy, Kathy D, Macpherson, Andrew J

“…Commensal bacteria in the lower intestine of mammals are 10 times as numerous as the body's cells. We investigated the relative importance of different immune…”
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The habitat, double life, citizenship, and forgetfulness of IgA by Macpherson, Andrew J., Geuking, Markus B., Slack, Emma, Hapfelmeier, Siegfried, McCoy, Kathy D.

“…Immunoglobulin A (IgA) is the main secretory immunoglobulin of mucous membranes and is powerfully induced by the presence of commensal microbes in the…”
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Engineering bacterial symbionts of nematodes improves their biocontrol potential to counter the western corn rootworm by Machado, Ricardo A. R., Thönen, Lisa, Arce, Carla C. M., Theepan, Vanitha, Prada, Fausto, Wüthrich, Daniel, Robert, Christelle A. M., Vogiatzaki, Evangelia, Shi, Yi-Ming, Schaeren, Olivier P., Notter, Matheus, Bruggmann, Rémy, Hapfelmeier, Siegfried, Bode, Helge B., Erb, Matthias

“…The western corn rootworm (WCR) decimates maize crops worldwide. One potential way to control this pest is treatment with entomopathogenic nematodes (EPNs)…”
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The lactonase BxdA mediates metabolic specialisation of maize root bacteria to benzoxazinoids by Thoenen, Lisa, Kreuzer, Marco, Pestalozzi, Christine, Florean, Matilde, Mateo, Pierre, Züst, Tobias, Wei, Anlun, Giroud, Caitlin, Rouyer, Liza, Gfeller, Valentin, Notter, Matheus D., Knoch, Eva, Hapfelmeier, Siegfried, Becker, Claude, Schandry, Niklas, Robert, Christelle A. M., Köllner, Tobias G., Bruggmann, Rémy, Erb, Matthias, Schlaeppi, Klaus

“…Root exudates contain specialised metabolites that shape the plant’s root microbiome. How host-specific microbes cope with these bioactive compounds, and how…”
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Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria by Stecher, Bärbel, Chaffron, Samuel, Käppeli, Rina, Hapfelmeier, Siegfried, Freedrich, Susanne, Weber, Thomas C, Kirundi, Jorum, Suar, Mrutyunjay, McCoy, Kathy D, von Mering, Christian, Macpherson, Andrew J, Hardt, Wolf-Dietrich

“…The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The parameters defining whether this community permits invasion…”
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Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance by Herzog, Mathias K.-M., Cazzaniga, Monica, Peters, Audrey, Shayya, Nizar, Beldi, Luca, Hapfelmeier, Siegfried, Heimesaat, Markus M., Bereswill, Stefan, Frankel, Gad, Gahan, Cormac G.M., Hardt, Wolf-Dietrich

“…Globally, enteropathogenic bacteria are a major cause of morbidity and mortality. 1-3 Campylobacter, Salmonella, Shiga-toxin-producing Escherichia coli, and…”
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Author Correction: Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity by Pfister, Simona P., Schären, Olivier P., Beldi, Luca, Printz, Andrea, Notter, Matheus D., Mukherjee, Mohana, Li, Hai, Limenitakis, Julien P., Werren, Joel P., Tandon, Disha, Cuenca, Miguelangel, Hagemann, Stefanie, Uster, Stephanie S., Terrazos, Miguel A., de Agüero, Mercedes Gomez, Schürch, Christian M., Coelho, Fernanda M., Curtiss, Roy, Slack, Emma, Balmer, Maria L., Hapfelmeier, Siegfried

“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21096-5…”
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