Search Results - "Hao, Qiongyu"

CCL2/CCR2 signaling in cancer pathogenesis by Hao, Qiongyu, Vadgama, Jaydutt V, Wang, Piwen

“…Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory cells to the site of tumor in tumorigenesis. A dysregulated expression…”
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AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer by Cao, Wei, Li, Jieqing, Hao, Qiongyu, Vadgama, Jaydutt V, Wu, Yong

“…Triple-negative breast cancer (TNBC) is an aggressive subset of breast carcinomas that lack expression of estrogen receptor (ER), progesterone receptor (PR),…”
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Tumor-Derived Exosomes in Tumor-Induced Immune Suppression by Hao, Qiongyu, Wu, Yong, Wu, Yanyuan, Wang, Piwen, Vadgama, Jaydutt V

“…Exosomes are a class of small membrane-bound extracellular vesicles released by almost all cell types and present in all body fluids. Based on the studies of…”
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Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor by Hao, Qiongyu, Diaz, Tanya, Verduzco, Alejandro del Rio, Magyar, Clara E., Zhong, Jin, Elshimali, Yahya, Rettig, Matthew B., Henning, Susanne M., Vadgama, Jaydutt V., Wang, Piwen

“…This study investigated the inhibitory effect of arctigenin, a novel anti-inflammatory lignan, on prostate cancer in obese conditions both in vitro and in vivo…”
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CircKIF5B Promotes Hepatocellular Carcinoma Progression by Regulating the miR-192 Family/XIAP Axis by Fei, Zhenghua, Wang, Yanfen, Gu, Yuyang, Xie, Rongrong, Hao, Qiongyu, Jiang, Yiyan

“…Background The long-term prognosis of HCC (hepatocellular carcinoma) with metastasis remains extremely poor. CircRNAs are promising as critical biological…”
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Oncogenic signaling pathway-related long non-coding RNAs for predicting prognosis and immunotherapy response in breast cancer by Li, Huamei, Liu, Hongjia, Hao, Qiongyu, Liu, Xianglin, Yao, Yongzhong, Cao, Meng

“…Background The clinical outcomes of breast cancer (BC) are unpredictable due to the high level of heterogeneity and complex immune status of the tumor…”
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Epigenetic repression of miR-17 contributed to di(2-ethylhexyl) phthalate-triggered insulin resistance by targeting Keap1-Nrf2/miR-200a axis in skeletal muscle by Wei, Jie, Hao, Qiongyu, Chen, Chengkun, Li, Juan, Han, Xikui, Lei, Zhao, Wang, Tao, Wang, Yinan, You, Xiang, Chen, Xiaoxuan, Li, Huasheng, Ding, Yuxin, Huang, Weihao, Hu, Yangyang, Lin, Shuirong, Shen, Heqing, Lin, Yi

“…Skeletal muscle insulin resistance is detectable before type 2 diabetes is diagnosed. Exposure to di(2-ethylhexyl) phthalate (DEHP), a typical environmental…”
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The role of PPM1D in cancer and advances in studies of its inhibitors by Deng, Wenhong, Li, Jieqing, Dorrah, Kimberly, Jimenez-Tapia, Denise, Arriaga, Brando, Hao, Qiongyu, Cao, Wei, Gao, Zhaoxia, Vadgama, Jay, Wu, Yong

“…[Display omitted] •PPM1D, an oncoprotein, negatively regulates several cancer suppressor pathways.•PPM1D has been found amplified and mutated in many human…”
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Celecoxib in breast cancer prevention and therapy by Li, Jieqing, Hao, Qiongyu, Cao, Wei, Vadgama, Jaydutt V, Wu, Yong

“…Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation,…”
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Comp34 displays potent preclinical antitumor efficacy in triple-negative breast cancer via inhibition of NUDT3-AS4, a novel oncogenic long noncoding RNA by Hao, Qiongyu, Wang, Piwen, Dutta, Pranabananda, Chung, Seyung, Li, Qun, Wang, Kun, Li, Jieqing, Cao, Wei, Deng, Wenhong, Geng, Qing, Schrode, Katrina, Shaheen, Magda, Wu, Ke, Zhu, Donghui, Chen, Qiao-Hong, Chen, Guanglin, Elshimali, Yahya, Vadgama, Jay, Wu, Yong

“…The abnormal PI3K/AKT/mTOR pathway is one of the most common genomic abnormalities in breast cancers including triple-negative breast cancer (TNBC), and…”
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Phytochemicals in Inhibition of Prostate Cancer: Evidence from Molecular Mechanisms Studies by Hao, Qiongyu, Wu, Yanyuan, Vadgama, Jaydutt V, Wang, Piwen

“…Prostate cancer is one of the leading causes of death for men worldwide. The development of resistance, toxicity, and side effects of conventional therapies…”
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Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo by Wu, Ke, Yu, Xiaoting, Huang, Zhimin, Zhu, Donghui, Yi, Xianghua, Wu, Ying-Li, Hao, Qiongyu, Kemp, 2nd, Kevin T, Elshimali, Yahya, Iyer, Roshni, Nguyen, Kytai Truong, Zheng, Shilong, Chen, Guanglin, Chen, Qiao-Hong, Wang, Guangdi, Vadgama, Jaydutt V, Wu, Yong

“…Epidemiologic evidence indicates that diabetes may increase risk of breast cancer (BC) and mortality in patients with cancer. The pathophysiological…”
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A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes‐Associated Breast Cancer by Hao, Qiongyu, Huang, Zhimin, Li, Qun, Liu, Dingxie, Wang, Piwen, Wang, Kun, Li, Jieqing, Cao, Wei, Deng, Wenhong, Wu, Ke, Su, Rui, Liu, Zhongmin, Vadgama, Jay, Wu, Yong

“…Diabetes is directly related to the risk of breast cancer (BC) occurrence and worsened BC prognosis. Currently, there are no specific treatments for…”
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Enhanced Chemoprevention of Prostate Cancer by Combining Arctigenin with Green Tea and Quercetin in Prostate-Specific Phosphatase and Tensin Homolog Knockout Mice by Hao, Qiongyu, Henning, Susanne M, Magyar, Clara E, Said, Jonathan, Zhong, Jin, Rettig, Matthew B, Vadgama, Jaydutt V, Wang, Piwen

“…The low bioavailability of most phytochemicals limits their anticancer effects in humans. The present study was designed to test whether combining arctigenin…”
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ZBED2 expression enhances interferon signaling and predicts better survival of estrogen receptor‐negative breast cancer patients by Liu, Dingxie, Hao, Qiongyu, Li, Jieqing, Li, Qun, Wang, Kun, Geng, Qing, Wu, Yutong, Vadgama, Jaydutt V., Wu, Yong

“…Abbreviations BC breast cancer CSCs cancer stem cells DMFS distant-metastasis-free survival ER estrogen receptor FPKM Fragments Per Kilobase of transcript…”
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CircRAD54L2 promotes triple-negative breast cancer progression by regulating the miR-888 family/PDK1 axis by He, Qiancheng, Hao, Qiongyu, Wu, Yanyuan, Vadgama, Jaydutt V., Jiang, Yiyan

“…The long-term prognosis of breast cancer with metastasis remains extremely poor. Genetic alterations in tumor cells result in cellular heterogeneity, promoting…”
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The overexpression and predictive significance of MMP-12 in esophageal squamous cell carcinoma by Han, Fei, Zhang, Suxia, Zhang, Long, Hao, Qiongyu

“…Matrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a major factor for tumor invasion and metastasis. MMP-12, as…”
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MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A by Liu, Kun, Hao, Qiongyu, Wei, Jie, Li, Gong-Hao, Wu, Yong, Zhao, Yun-Feng

“…AIM:PDE5A is a leading factor contributing to cGMP signaling and cardiac hypertrophy. However, microRNA-mediated posttranscriptional regulation of PDE5A has…”
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Abstract C109: Identifying a novel metabolic reprogramming strategy to inhibit diabetes-associated TNBC in African American by Hao, Qiongyu, Wu, Yong, Wu, Yanyuan, Vadgama, Jaydutt

“…Abstract Cancer cells have an increased glucose metabolism, primarily characterized by augmented glucose uptake and aerobic glycolysis, converting glucose into…”
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Evaluation of myocardial viability in patients with acute myocardial infarction: Layer-specific analysis of 2-dimensional speckle tracking echocardiography by Liu, Kun, Wang, Yan, Hao, Qiongyu, Li, Gonghao, Chen, Peng, Li, Dongye

“…The value of layer-specific two-dimensional speckle tracking echocardiography (LS2D-STE) for evaluating viable myocardium (VM) in patients with acute…”
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