Search Results - "Hao, Mingjing"
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A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non–small cell lung cancers
Published in The Journal of biological chemistry (01-07-2022)“…Tumor angiogenesis is closely associated with the metastasis and progression of non–small cell lung cancer (NSCLC), a highly vascularized solid tumor. However,…”
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Mechanism of Self-Assembled Celastrol-Erianin Nanomedicine for treatment of breast cancer
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-11-2024)“…•Nanoparticles for breast cancer treatment, termed CEN, were prepared by self-assembling the natural compounds celastrol and erianin.•Using the ABPP method,…”
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The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose
Published in Chemico-biological interactions (25-02-2022)“…Aerobic glycolysis is a hallmark of malignant tumor. Here, the hyperactive glycolysis in multidrug-resistant A549/Taxol cells was demonstrated to be essential…”
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Dissection of Targeting Molecular Mechanisms of Celastrol-induced Nephrotoxicity via A Combined Deconvolution Strategy of Chemoproteomics and Metabolomics
Published in International journal of biological sciences (01-01-2024)“…Celastrol (Cel), derived from the traditional herb fordii Hook. f., has anti-inflammatory, anti-tumor, and immunoregulatory activities. Renal dysfunction,…”
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Chemoproteomics Reveals Glaucocalyxin A Induces Mitochondria‐Dependent Apoptosis of Leukemia Cells via Covalently Binding to VDAC1
Published in Advanced biology (01-02-2024)“…Chronic myelogenous leukemia (CML) that is resistant to tyrosine kinase inhibitors is one of the deadliest hematologic malignancies, and the T315I mutation in…”
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